Guest guest Posted February 29, 2008 Report Share Posted February 29, 2008 Hi GFCFMom...from Sue, It sound like your son's tiredness and irritability is DOSE related...with Carnosine. Keep in mind that Carnosine is repairing old cells... Like gutting an old n house down to the bone...then revitalizing like new... so the tearing down stage will have lots of detox. When I wore the LW Carnosine booster patches...at the beginning about 8 months ago... I could only wear them for 2 hours before getting those same symptoms...tired... Then after 4 hours I was irritable and by 6 hours I had a headache. SO--- I realized 2 hours was the maximum time for me for about a month... (Recommended wearing time is 12 hours.)... With the patches... but it's easy to take them off then the symptoms GO AWAY in a short time...especially with Activated CHARCOAL.. Then I wore them them every OTHER day as instructed.. --SLOWLY working my hours up ONE Hour at a time --- up to 12 hours... after 6 months of wearing them. Note:.. I'm 61..so I have lots of OLD cells to repair... ( Carnosine is known to increase longevity up to 25%..so it's often known for anti--aging on the website). ( They are Very cost effective that way..since we can re-use them until all the hours are used up. They lasted SEVERAL months at first. with BOTH my husband and I using them.) Anyway... with the RIGHT DOSAGE..I have great results as in paragraph two below. Hopefully your SON will find the right dosage for him with the source you have as well.)) Below are the benefits of Carnosine..... Google Carnitine..and you'll see how different it is. To: mb12 Valtrex Sent: Sunday, February 24, 2008 2:30 AM Subject: CARNOSINE for SEIZURES and ASD & more . Hi from Sue, While Carnosine is most known for it's antiglycation.."turning old cells into new cells" associated with anti-aging benefits... it has numerous neurological benefits as Dr. Chez found for children with ASD in his double blind studies summarized below. Note the benefits for SEIZURES as well. I find that the LW Yage Carnosine patch helps me with my memory, focus, getting things done and motivation...not to mention it's wonderful rejuvenation of cells due to getting rid of metabolic wastes !... I also have a study showing Carnosine killed all 7 types of cancer found in a Petri dish. so if anyone wants that study let me know....at st@... ... See BELOW for summaries on Carnosine studies.. by another product.(but keep in mind oral supplementation is not as effective as the LW patches in most cases) More info is at the very bottom of this post regarding the NON trandermal LW Yage Carnosine patches. L - C A R N O S I N EWhat is Carnosine? The naturally-occurring amino acid is found within the human body, a by-product of proteins digested within the body. The deep frontal part of the brain (entorhinal cortex) is believed to be a site where carnosine tends to accumulate. It may interact with zinc in that area, as well as having effects on GABA, a brain neurotransmitter, which by a complex chemical reaction forms homo-carnosine.What Studies Have Been Done with Carnosine?Rat and animal studies have been done with carnosine looking at "neuroprotection." These investigations aimed to examine protective action since carnosine may be protective of muscle and nervefunction. There have been no studies that have shown any evidence of toxicity or teratogenicity in animals where carnosine has been studied. Few scientifically-validated human studies have been conducted, however, and most of the information one finds about carnosine's claims are of the quality found on the internet. Claims have been made for generic carnosine/carnosine formulations aiding in combating a range of maladies from Alzheimer's to body building.Why Carnosine, then?Recent MRI studies by Petroff and colleagues (2001) examining levels of brain chemistry showed a relationship between homo-carnosine and GABA in temporal lobe and generalized myoclonic epilepsies. These authors described homo-carnosine levels that may correlate with SEIZURE CONTROL even when GABA response is defective in human studies. Dr. Chez was intrigued by the results of this study, and thus began a study in June, 2001 that aimed to test if supplementing carnosine orally could enhance seizure protection in children who were already on anticonvulsants and who had recurrent SEIZURES despite being on standard drug therapy. He hypothesized that the addition of carnosine could DECREASE seizure frequency and so began an open-label study of carnosine which he acquired via an industrial chemical company.The Open-Label StudyA total of 75 children, who had "failed" multiple antiepilepticmedications in an effort to stop their seizures (including steroids and the Ketogenic diet) with histories of partial or generalized EPILEPSY entered the open-label study. The majority had fronto-temporal lobe seizures, or generalized epilepsy. Approximately 25% had EEGs to directly compare before and after starting the carnosine. Many patients had reductions in seizure frequency, but without EEG correlation. Two sisters with hypsarrythmia/Lennox-Gastaut variant both showed dramatic improvements in EEG amplitude, spike frequency, and background activity. In three other patients with primary or secondary generalized spike and wave patterns or Lennox-Gastaut type patterns, EEG amplitude and spike frequency improved with carnosine in dosages of 800-2,000 mg. per day. Dosage was titrated upward depending upon bodyweight. No side effects were reported.Unexpectedly, parental diaries showed a pattern of comments related to gains in cognitive domains including language, alertness, energy levels, and even gross motor ability. Dr. Chez was motivated by such reports in addition to comments from other professionals that worked simultaneously with the children (e.g., speech therapists) who, unaware that children were on the new supplement, spontaneously stated that individual children were showing incremental gains not previously seen. Expressive language was described as more fluent, eye contact more frequent, and interest in the environment was more prominent. Dr. Chez thought that this supplement could be of benefit to children with autism or PDD and so began to give it to children with such diagnoses in an open-label trial. Indeed, parents reported benefits in their children after as few as 2 weeks, in the areas of socialization, expressive language, alertness level, energy level, adaptation to change, and curiously, gross motor planning.The Double-Blind StudyBecause of the remarkable cognitive improvements in language, speech production and school performance as well as social alertness, Dr. Chez felt it important to study the effect of the supplement in children with Autistic Spectrum Disorders. Children were included in this study if they had histories of abnormal EEG, and had previously responded to cognitive-enhancing dementia medications (as part of a controlled study at the office) or to anti-convulsants. A double-blind placebo controlled study with carnosine was begun. Children were randomly placed on either active carnosine or placebo. Expressive and receptive language measures, two autism rating scales, and parent rating analog scales were administered at the start and completion of the study. Results of this study indicated clinically meaningful changes in many aspects of autistic features, and also showed that the carnosine supplement improved children's expressive and receptive language significantly. This is the only dietary supplement to date studied in a double-blind fashion in autism.Who Benefits and What are the Side Effects?The majority of children with either epilepsy or autism treated in open label studies by Dr. Chez benefited from carnosine supplementation. Dr.Chez estimates that approximately 10% of children who have been on the carnosine supplement have had reports of no improvement. A very small percentage (less than 5% of children with epilepsy or autistic spectrum disorders) have shown increased physicalhyperactivity or verbal hyperactivity, but we are unable to ascertain if these reports are directly related to the carnosine supplement. No sleep disturbances were reported as a result of carnosine therapy even in dosages up to 3,000 mg. a day. No abdominal side effects, skin rashes, or any changes in anticonvulsant blood levels, liver functions or hematological studies. No patients had any urinary changes or bowel habit changes from the carnosine.Many children on the autistic spectrumwere reported to increase their range of food choices with an improved range ofappetite.Responses have been seen in generalized epilepsies, focal seizure disorders, autism, PDD, and head injury to date. Because of its effect on entorhinal cortex, improvements in Alzheimer's disease or other frontal lobe encephalopathy may be possible. Any syndrome that involves apraxia or expressive language delay maybenefit from this. Concurrent studies are currently being run or planned in areas ofattention disorder, Tourette's syndrome, and various learning disability syndromes of the nonverbal type. PS.....from Sue..... One type of LW Yage patches give a continuous boost of Carnosine for a full 12 -+++hour time period since they activate the body to produce more of it's OWN carnosine. ( I say ONE type..since YAGE patches come in sets of either 1. One pkg. of Carnosine booster..PLUS one pkg. of GSH boosters OR 2. TWO pks. of the GSH =( Glutathione boosters ) alone.) They are NON transdermal...and work using resonant energy (similar to radio waves) to achieve this effect...when activated by the bodies INFRARED heat even up to 6 inches away from the body....so they will work ON CLOTHING as well as the skin. There are many studies done on the effectiveness of the various patches shown on the website... www.lifewave.com/jhennings. and a short 8 minute video called The Lifewave Report that explains the technology. I have a lengthy report that explains the Science behind these nano tech NON transdermal patches ----that even many Olympians and Pro and College athletes use as well. ( The website above is from another parent in this group who has 6 children many with chronic health issues...including ASD.) While I have posted our own NON profit site in the past....which has generated over $300.00 in proceeds to Autism Research Institute.... -----.I also want to "PAY IT FORWARD" to this and other parents who become members of LW ( 25.00 discount membership) ---from this MB12 group... as we are all trying to help one another. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 29, 2008 Report Share Posted February 29, 2008 Sue, Thank you so much. This is great, inspiring, information. gfcmom > > Hi GFCFMom...from Sue, > > It sound like your son's tiredness and irritability is DOSE related...with Carnosine. > Keep in mind that Carnosine is repairing old cells... Like gutting an old n house > down to the bone...then revitalizing like new... so the tearing down stage will have lots of detox. > > When I wore the LW Carnosine booster patches...at the beginning about 8 months ago... > I could only wear them for 2 hours before getting those same symptoms...tired... > Then after 4 hours I was irritable and by 6 hours I had a headache. > > SO--- I realized 2 hours was the maximum time for me for about a month... > > (Recommended wearing time is 12 hours.)... With the patches... but it's easy to take them off > then the symptoms GO AWAY in a short time...especially with Activated CHARCOAL.. > > Then I wore them them every OTHER day as instructed.. > --SLOWLY working my hours up ONE Hour at a time --- up to 12 hours... after 6 months of wearing them. > Note:.. I'm 61..so I have lots of OLD cells to repair... ( Carnosine is known to increase longevity > up to 25%..so it's often known for anti--aging on the website). > > ( They are Very cost effective that way..since we can re-use them until all the hours are used up. > They lasted SEVERAL months at first. with BOTH my husband and I using them.) > > Anyway... with the RIGHT DOSAGE..I have great results as in paragraph two below. > Hopefully your SON will find the right dosage for him with the source you have as well.)) > > Below are the benefits of Carnosine..... Google Carnitine..and you'll see how different it is. > To: mb12 Valtrex > Sent: Sunday, February 24, 2008 2:30 AM > Subject: CARNOSINE for SEIZURES and ASD & more . > > Hi from Sue, > While Carnosine is most known for it's antiglycation.. " turning old cells into new cells " > associated with anti-aging benefits... it has numerous neurological benefits as > Dr. Chez found for children with ASD in his double blind studies summarized below. > Note the benefits for SEIZURES as well. > > I find that the LW Yage Carnosine patch helps me with my memory, focus, getting things done > and motivation...not to mention it's wonderful rejuvenation of cells due to getting > rid of metabolic wastes !... > I also have a study showing Carnosine killed all 7 types of cancer found in a Petri dish. > so if anyone wants that study let me know....at st@... ... > > See BELOW for summaries on Carnosine studies.. > by another product.(but keep in mind oral supplementation is not as effective as the LW patches in most cases) > More info is at the very bottom of this post regarding the NON trandermal LW Yage Carnosine patches. > > L - C A R N O S I N E > > What is Carnosine? > > The naturally-occurring amino acid is found within the human body, a by-product of > proteins digested within the body. The deep frontal part of the brain (entorhinal > cortex) is believed to be a site where carnosine tends to accumulate. It may > interact with zinc in that area, as well as having effects on GABA, a brain > neurotransmitter, which by a complex chemical reaction forms homo-carnosine. > > What Studies Have Been Done with Carnosine? > Rat and animal studies have been done with carnosine looking at " neuroprotection. " > These investigations aimed to examine protective action since carnosine may be > protective of muscle and nervefunction. There have been no studies that have shown > any evidence of toxicity or teratogenicity in animals where carnosine has been > studied. Few scientifically-validated human studies have been conducted, however, > and most of the information one finds about carnosine's claims are of the quality > found on the internet. Claims have been made for generic carnosine/carnosine > formulations aiding in combating a range of maladies from Alzheimer's to body > building. > > Why Carnosine, then? > Recent MRI studies by Petroff and colleagues (2001) examining levels of brain > chemistry showed a relationship between homo-carnosine and GABA in temporal > lobe and generalized myoclonic epilepsies. These authors described homo-carnosine > levels that may correlate with SEIZURE CONTROL even when GABA response is defective > in human studies. Dr. Chez was intrigued by the results of this study, and thus began > a study in June, 2001 that aimed to test if supplementing carnosine orally could > enhance seizure protection in children who were already on anticonvulsants and who > had recurrent SEIZURES despite being on standard drug therapy. He hypothesized that > the addition of carnosine could DECREASE seizure frequency and so began an > open-label study of carnosine which he acquired via an industrial chemical company. > > The Open-Label Study > A total of 75 children, who had " failed " multiple antiepilepticmedications in an effort > to stop their seizures (including steroids and the Ketogenic diet) with histories of > partial or generalized EPILEPSY entered the open-label study. The majority had > fronto-temporal lobe seizures, or generalized epilepsy. Approximately 25% had EEGs to > directly compare before and after starting the carnosine. Many patients had > reductions in seizure frequency, but without EEG correlation. Two sisters with > hypsarrythmia/Lennox-Gastaut variant both showed dramatic improvements > in EEG amplitude, spike frequency, and background activity. In three other patients with > primary or secondary generalized spike and wave patterns or Lennox-Gastaut type > patterns, EEG amplitude and spike frequency improved with carnosine in dosages > of 800-2,000 mg. per day. Dosage was titrated upward depending upon bodyweight. > No side effects were reported.Unexpectedly, parental diaries showed a pattern of > comments related to gains in cognitive domains including language, alertness, > energy levels, and even gross motor ability. Dr. Chez was motivated by such reports > in addition to comments from other professionals that worked simultaneously with > the children (e.g., speech therapists) who, unaware that children were on the new > supplement, spontaneously stated that individual children were showing incremental > gains not previously seen. Expressive language was described as more fluent, eye > contact more frequent, and interest in the environment was more prominent. > Dr. Chez thought that this supplement could be of benefit to children with autism or > PDD and so began to give it to children with such diagnoses in an open-label trial. > Indeed, parents reported benefits in their children after as few as 2 weeks, in the > areas of socialization, expressive language, alertness level, energy level, adaptation > to change, and curiously, gross motor planning. > > The Double-Blind Study > Because of the remarkable cognitive improvements in language, speech production > and school performance as well as social alertness, Dr. Chez felt it important to > study the effect of the supplement in children with Autistic Spectrum Disorders. > Children were included in this study if they had histories of abnormal EEG, and > had previously responded to cognitive-enhancing dementia medications (as part of a > controlled study at the office) or to anti-convulsants. A double-blind placebo > controlled study with carnosine was begun. Children were randomly placed on either > active carnosine or placebo. Expressive and receptive language measures, two > autism rating scales, and parent rating analog scales were administered at the start > and completion of the study. Results of this study indicated clinically meaningful > changes in many aspects of autistic features, and also showed that the carnosine > supplement improved children's expressive and receptive language significantly. This > is the only dietary supplement to date studied in a double-blind fashion in autism. > > Who Benefits and What are the Side Effects? > The majority of children with either epilepsy or autism treated in open label studies > by Dr. Chez benefited from carnosine supplementation. Dr.Chez estimates that > approximately 10% of children who have been on the carnosine supplement have > had reports of no improvement. A very small percentage (less than 5% of children > with epilepsy or autistic spectrum disorders) have shown increased physical > hyperactivity or verbal hyperactivity, but we are unable to ascertain if these reports > are directly related to the carnosine supplement. No sleep disturbances were > reported as a result of carnosine therapy even in dosages up to 3,000 mg. a day. > No abdominal side effects, skin rashes, or any changes in anticonvulsant blood > levels, liver functions or hematological studies. No patients had any urinary changes > or bowel habit changes from the carnosine.Many children on the autistic spectrum > were reported to increase their range of food choices with an improved range of > appetite.Responses have been seen in generalized epilepsies, focal seizure > disorders, autism, PDD, and head injury to date. Because of its effect on entorhinal > cortex, improvements in Alzheimer's disease or other frontal lobe encephalopathy may > be possible. Any syndrome that involves apraxia or expressive language delay may > benefit from this. Concurrent studies are currently being run or planned in areas of > attention disorder, Tourette's syndrome, and various learning disability syndromes of > the nonverbal type. > > > PS.....from Sue..... > One type of LW Yage patches give a continuous boost of Carnosine for a full 12 -++ +hour > time period since they activate the body to produce more of it's OWN carnosine. > > ( I say ONE type..since YAGE patches come in sets of either > 1. One pkg. of Carnosine booster..PLUS one pkg. of GSH boosters > OR > 2. TWO pks. of the GSH =( Glutathione boosters ) alone.) > > They are NON transdermal...and work using resonant energy (similar to radio waves) > to achieve this effect...when activated by the bodies INFRARED heat even up to 6 inches away from the body....so they will work ON CLOTHING as well as the skin. > > There are many studies done on the effectiveness of the various patches > shown on the website... www.lifewave.com/jhennings. and a short 8 minute video > called The Lifewave Report that explains the technology. > > I have a lengthy report that explains the Science behind these > nano tech NON transdermal patches ----that even many > Olympians and Pro and College athletes use as well. > > ( The website above is from another parent in this group who has 6 children many with chronic health > issues...including ASD.) While I have posted our own NON profit site in the past....which has > generated over $300.00 in proceeds to Autism Research Institute.... > -----.I also want to " PAY IT FORWARD " to this and other parents > who become members of LW ( 25.00 discount membership) ---from this MB12 group... > as we are all trying to help one another. > Quote Link to comment Share on other sites More sharing options...
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