Re: epinephephrine for injection

[Guest guest]

Jimminy , how big is that brain of yours? Thanks for that little tidbit!Lynette I Iles MD 214 South Iowa Ste 3 Washington IA 52353 Flexible Family Care'Modern medicine the old-fashioned way'

This e-mail and attachments may contain information which is confidential and is only for the named addressee. If you have received this email in error, please notify the sender immediately and delete it from your computer.

[Guest guest]

I'm a little confused on these prefilled epi syringes.

The epipen says...

EpiPen® 0.3 mg EPINEPHRINE AUTO-INJECTORAuto-Injector for Intramuscular Injection of EpinephrineFor the Emergency Treatment of Allergic Reactions (Anaphylaxis)Delivers a single 0.3 mg intramuscular dose of epinephrine from epinephrine injection, USP, 1:1000 (0.3 mL).

But a lot of these other prefilled syringes say 1:10,000.

For example, the

http://www.schoolkidshealthcare.com/product/497.html

the ndc # is 0548-1016-00

item #

item description

0548-1016-00

EPINEPHRINE INJ 1:10,000(.1MG/ML) 10ML MINI-JET 21

But these are all 1:10,000 -- which is the IV concentration, yes?

I searched and searched, but could not find a prefilled 1:1,000 epinephrine -- other than the epipen.

Anyone else with luck?

The non-prefilled are pretty cheap at 76 cents per vial -- but you would have to draw up the correct dosage -- but still can't beat the price.

http://www.buyemp.com/product/1123013.html

Epinephrine Ampule

Epinephrine Ampule Description:

Manufacturer is Hospira.

Epinephrine Ampule

item #

item description

price

quantity

07241-01-13

EPINEPHRINE 1:1,000 1ML AMPULE

$0.76

The more expensive Twinject...

Home » IV & Pharmaceuticals » Epi-Pen Auto Injectors

Twinject Epinephrine

Twinject Epinephrine Description:

The Only Available Auto-injector With 2 Doses of Epinephrine in 1 Device.

Features:

Unique 2-in-1 device eliminates the need for 2 single-dose injectors Auto-injector enables rapid delivery of epinephrine Prefilled syringe provides manual delivery of second dose Available in 2 weight-appropriate doses: 0.3 mg (for individuals 66 lbs and over)and 0.15 mg (for individuals between 33 and 66 lbs) Clear window indicator confirms viability of medication Slim, crush-resistant case protects Twinject in handbags, backpacks, and travel kits; includes metal pocket clip for added security Thin, 25-gauge needle Permanently attached WrapLabel™ ensures that step-by-step instructions are immediately available to patients or caregivers anywhere, anytime

Twinject Epinephrine

item #

item description

U of M

price

quantity

Locke, MD

700-01

TWINJECT EPINEPHRINE 1:1000 USP 0.3MG

Each

$64.95

700-02

TWINJECT EPINEPHRINE 1:1000 USP 0.3MG - TWO PACK

Each

$119.95

701-01

TWINJECT EPINEPHRINE 1:1000 USP 0.15MG

Each

$64.95

701-02

TWINJECT EPINEPHRINE 1:1000 USP 0.15MG - TWO PACK

Each

$119.95

From: [mailto: ] On Behalf Of Locke's in ColoradoSent: Friday, February 08, 2008 6:34 PMTo: Subject: RE: epinephephrine for injection

Lawrence,

Are you sure it's the correct concentration premixed?

If you are giving an IV preparation, IM -- it could be the 1:10,000 concentration you are giving IM -- and therefore underdosing.

I'm sure you've checked that, but was just curious.

What company do you order from?

http://circ.ahajournals.org/cgi/content/full/112/24_suppl/IV-143

–Absorption and subsequent achievement of maximum plasma concentration after subcutaneous administration is slower and may be significantly delayed with shock.10,11 Thus, intramuscular (IM) administration is favored.

Administer epinephrine by IM injection early to all patients with signs of a systemic reaction, especially hypotension, airway swelling, or definite difficulty breathing.

Use an IM dose of 0.3 to 0.5 mg (1:1000) repeated every 15 to 20 minutes if there is no clinical improvement.

–Administer IV epinephrine if anaphylaxis appears to be severe with immediate life-threatening manifestations.12

Use epinephrine (1:10 000) 0.1 mg IV slowly over 5 minutes. Epinephrine may be diluted to a 1:10 000 solution before infusion.

An IV infusion at rates of 1 to 4 µg/min may prevent the need to repeat epinephrine injections frequently.13

Locke, MD

From: [mailto: ] On Behalf Of lawrence lyonSent: Friday, February 08, 2008 4:41 PMTo: practice improvementSubject: epinephephrine for injection

the previously mentioned epi in the screw together injector is actually only $4.20, not $7.00.

it states it is for IV use, however, i would be injecting it sub-Q.

much, much cheaper than an EpiPen.

LL

Never miss a thing. Make Yahoo your homepage.