Re: HEY GUYS- Q; on Diflucan, Candida??

[Guest guest]

,

Glad you're doing better.

I haven't seen depression in my kids with an antifungal, but nothing would

surprise me... everyone is different.

Regarding Nizoral, it actually seemed to work better than Diflucan in one of

my kids... it really helped him a lot... pretty dramatic. Dr. G said that

Nizoral has the added benefit of an effect on the adrenal-cortical axis

(sp?) that can be helpful sometimes.

Caroline

> From: <javanfirkins@...>

> Reply-< >

> Date: Sat, 21 Apr 2007 01:39:59 +0000

> < >

> Subject: HEY GUYS- Q; on Diflucan, Candida??

>

> Any type of depressive/mood reactions with Diflucan? Anyone?? ; and

> what do you all think of Nizoral (Ketoconazole?) Is it more risky?

[Guest guest]

Diflucan die-off *definitely* included some dramatic mood swings in my

kiddo. He was very fragile/sensitive and would burst into tears at

the slightest thing. He did eventually even out, but in our case,

die-off took nearly 4 weeks.

The die-off from Nizarol has always been a " gentler " experience for him.

I'm guessing that what you're experiencing is a die-off reaction,

. Hang in there! I promise you'll start feeling better.

HTH,

Donna

>

> ,

>

> Glad you're doing better.

>

> I haven't seen depression in my kids with an antifungal, but nothing

would

> surprise me... everyone is different.

>

> Regarding Nizoral, it actually seemed to work better than Diflucan

in one of

> my kids... it really helped him a lot... pretty dramatic. Dr. G

said that

> Nizoral has the added benefit of an effect on the adrenal-cortical axis

> (sp?) that can be helpful sometimes.

>

> Caroline

>

>

> > From: <javanfirkins@...>

> > Reply-< >

> > Date: Sat, 21 Apr 2007 01:39:59 +0000

> > < >

> > Subject: HEY GUYS- Q; on Diflucan, Candida??

> >

> > Any type of depressive/mood reactions with Diflucan? Anyone?? ; and

> > what do you all think of Nizoral (Ketoconazole?) Is it more risky?

>

[Guest guest]

Well those sound comforting;

I do have have the choice of trying the Nizoral instead; being that it

is less expensive...

What dose are you kids taking,? Is it in combo with anything else at

the time, or previously?

Since the doctors I'm dealing with aren't 'used to,' the type of

treatment protocol Dr. G, uses, the amounts might be different for me

weighing approx. 65-kg; but I'm curious what Dr. G recommends for you

guys.

Any raised liver enzymes in your children; any concerns or adjustments

have to be made due to it? I'm curious-that's a conern of mine I'm

sure you understand!.. ;-P

I also am curious if it would be wise to seek to have some time 'off'

from the Diflucan before I started Nizoral? if they are willing.

I think I read Dr. G doesn't like long breaks in treatments?

But your kids are doing pretty well on them, huh? That's great. What

have some of the main improvements been that you've seen?

-

> >

> > ,

> >

> > Glad you're doing better.

> >

> > I haven't seen depression in my kids with an antifungal, but nothing

> would

> > surprise me... everyone is different.

> >

> > Regarding Nizoral, it actually seemed to work better than Diflucan

> in one of

> > my kids... it really helped him a lot... pretty dramatic. Dr. G

> said that

> > Nizoral has the added benefit of an effect on the adrenal-cortical

axis

> > (sp?) that can be helpful sometimes.

> >

> > Caroline

> >

> >

> > > From: <javanfirkins@>

> > > Reply-< >

> > > Date: Sat, 21 Apr:39:59 +0000

> > > < >

> > > Subject: HEY GUYS- Q; on Diflucan, Candida??

> > >

> > > Any type of depressive/mood reactions with Diflucan? Anyone?? ; and

> > > what do you all think of Nizoral (Ketoconazole?) Is it more risky?

> >

>

[Guest guest]

Hi ,

On Dr. G's protocol, we are switched directly from one anti-fungal to

the other, in a directly corresponding dose, without a break.

I'm afraid we here in the States never converted to metric, but I

found a handy-dandy conversion chart online. My 9-year-old son

weighs 62 lbs., which translates to 28.123 kg. He gets 1/2 of a 200

mg. pill at bedtime. Just as a caution, I don't know if weight is the

only factor that Dr. G takes into consideration when deciding on the

correct dose.

Here's the URL of the conversion chart, in case anyone's interested:

http://www.worldwidemetric.com/metcal.htm

Donna

> > >

> > > ,

> > >

> > > Glad you're doing better.

> > >

> > > I haven't seen depression in my kids with an antifungal, but nothing

> > would

> > > surprise me... everyone is different.

> > >

> > > Regarding Nizoral, it actually seemed to work better than Diflucan

> > in one of

> > > my kids... it really helped him a lot... pretty dramatic. Dr. G

> > said that

> > > Nizoral has the added benefit of an effect on the adrenal-cortical

> axis

> > > (sp?) that can be helpful sometimes.

> > >

> > > Caroline

> > >

> > >

> > > > From: <javanfirkins@>

> > > > Reply-< >

> > > > Date: Sat, 21 Apr:39:59 +0000

> > > > < >

> > > > Subject: HEY GUYS- Q; on Diflucan, Candida??

> > > >

> > > > Any type of depressive/mood reactions with Diflucan? Anyone??

; and

> > > > what do you all think of Nizoral (Ketoconazole?) Is it more

risky?

> > >

> >

>

[Guest guest]

Hey -

I have comments in the text below at the ***'s....

--- <javanfirkins@...> wrote:

> I've known CANDIDA was a big risk even if it wasn't

> one before. I was

> unable to use the 'rest room' for days due to the

> rupture and swelling

> that caused my intestine to be closed/squeezed

> off...

***** Have you been tested for anaerobic bacterial

infections in the gut? The ones that thrive in the

absence of oxygen? I think C-diff is one of those.

If you haven't had it checked, it would be a very good

idea to.

> I'm doing well now; the infection is gone, and has

> been over one month

> now.

> -It was HARD but I was 'sorta' able to get my doctor

> to work with me on

> the use of an antifungal after going through such

> antibiotic use... a

> LOT of resistance.

**** Yes it is very hard to obtain even after repeated

yeast infections, thrush, etc etc etc.

>

> I was taking 150 MG Diflucan once a day; and it has

> been about 15 days

> now... That is a regular treatment phase- now what?

**** Is that the total # of days your doctor gave you

or are they agreeing temporarily to continue it?

> I read Dr.

> Goldberg says that 'yest die off' takes 10-14 days-

> I've been on mine 15

> now.

**** Die off is an average, takes a lot less w/some,

many don't have it at all, and it rarely exceeds (but

has for a few rare kids) 30 days. There's not really

a stop time for it. You are looking for a change

attached to the number of days and it usually isn't

going to be that dramatic for ya, especially not with

the amount of significant infection you've had to deal

with recently and how very activated your immune

system has likely been.

I know the dose I am taking is 'lower' than he

> likes it to be

> (since I'm a 65 Kilogram adult)- but it seems like

> when I raised it to

> twice a day (150 MG x daily)- I didn't have 'D' or

> constipation (common

> die off reactions); etc...

> I just noticed I felt very depressed and like

> Diflucan wasn't

> 'chemically' syncing with my body well...

****** You don't need to go any higher than 200mg per

day. You're not that far off and I'd recommend for

now being very grateful for that amount and not

pushing it with your doctor, and not doubling up

hoping to get more benefit but losing another day of

treatment.

>

> Any type of depressive/mood reactions with Diflucan?

> Anyone?? ; and

> what do you all think of Nizoral (Ketoconazole?) Is

> it more risky?

******* It could happen whether others have noticed it

or not. But I would recommend giving it well over a

month (if your docs are considering allowing an

extension) ... unless they'd be ok w/Nizoral. Your

doc could get ticked if you say this med you begged

for (and he only gave it to humor you) isn't helping,

can you try another. I'd tred lightly there. But

yeah, sometimes Nizoral works a little better for

others. I think it did for me until I started having

acute gastritis with it.

But , I don't think you'll experience any

dramatic magic on either one of them. You were

exposed to very high levels of bacteria and even once

these meds start helping you, it may still take quite

a bit of time for the immune system to calm down.

They should help you, and the Diflucan may already be

working on your immune system, and if it is, and it's

taking a shift, depression could be part of that

symptom. BUT>>>> ... another paragraph on that....

.... In my experience, my depression from meds comes

from an extreme disappointment (even though sometimes

it starts out subconcious) that I don't feel as much

better as I had hoped I would once I finally

" acquired " the medication I was putting so much faith

in to help me. I've had these ups and downs for 3+

years now and it's taken me a lot of time to figure

out what was, wasn't, and how so many various things

were affecting how I was doing. I've had dramatic

improvements at times and then others not had nearly

the effect. It has been overwhelming sometimes, and

only over a period of time have I been able to

experience the true impact of the treatment -

sometimes thinking something wasn't helping until

after I was off and then returned.

Hang in there, give it time. Do not try to observe

daily how you are feeling, or believe me, from my

experience, you will become hypersomatic and it will

significantly diminish the benefit of the meds. Allow

yourself 15 minutes per day (or morning and night

maybe to start), and journal what and how you've been

feeling. Set the timer, experience it, document it,

and then walk away and do not allow yourself too much

time to think and self-observe. That is, if you're

anything like me. Even though I'm a whole lot better

on Diflucan and Doxycycline, my PANDAS, my OCD and

anxiety - are not magically gone and I still require

behavior modification and support until I do reach

that point. But I'm often startled to find that -

despite perceiving my feeling of wellness not being

what I'd like - I am often surprised when I 'look up'

and see how much I recently accomplished because I was

more focused and more energetic than before and

suddenly see that I truly am being helped by the meds

even before I start feeling it as wellness.

This has truly been hard for me to learn. Expect the

meds to help you heal physically and then the ability

to function much better mentally and emotionally can

follow. I think kids may have faster and more obvious

responses because they live " in the moment " and one

day at a time.

Be sure to keep in mind any other medication changes

you've had that could be having a delayed impact.

Meds you were off of during illness and perhaps

restarted and/or did not continue, and consider the

time frames for those too.

That's not saying that the Diflucan isn't agreeing

with you. I'm just suggesting to think very carefully

about what you want to see, what you are seeing, and

perhaps not risk rocking the boat with your resistant

doc to get Nizoral until he starts refusing to give

you Diflucan... just my thoughts. Based on my own

experience, which does not apply to everyone ... just

me.

HTH-

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