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Re: Two antifungals simulaneously?

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You can give both. Nystatin is a non-systemic yeast killer so it

only kills yeast with direct contact and usually does not cause

possible liver issues.

Cheryl

On Jan 9, 2008, at 7:00 AM, rohi_03 wrote:

> Hi,

> I was wondering if any kids are on 2 antifungals simulataneously? My 4

> yr old was started on diflucan a month back. He immediately showed

> better focus and attention and was in his best behavior. However,

> since last week, he has started mouthing stuff again, being obsessive,

> silly, giggling and his attention/focus has gone down again. He has

> been a little sick with cough/cold but apart from that, I haven't

> changed anything else (oh, except that I fed him organic turkey breast

> for the first time right around the time his behaviors changed). His

> doctor had prescribed both diflucan and nystatin for him a month ago,

> but I started with the diflucan only. I am not sure if it is advisable

> to give both nystatin and diflucan at the same time. Please advise. I

> am really devastated that he has lost a lot of the tremendous gains he

> made when he started diflucan.

> Thanks a lot

> Rohini

>

>

>

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Hi Rohini,

I did it and I think it helped a bit. Nistatin is suposedly

(spelling?) not sistemic, it acts just through direct contact and

not absorved. I´d also consider to rise fluco dose...what´s his dose

currently?

>

> Hi,

> I was wondering if any kids are on 2 antifungals simulataneously?

My 4

> yr old was started on diflucan a month back. He immediately showed

> better focus and attention and was in his best behavior. However,

> since last week, he has started mouthing stuff again, being

obsessive,

> silly, giggling and his attention/focus has gone down again. He

has

> been a little sick with cough/cold but apart from that, I haven't

> changed anything else (oh, except that I fed him organic turkey

breast

> for the first time right around the time his behaviors changed).

His

> doctor had prescribed both diflucan and nystatin for him a month

ago,

> but I started with the diflucan only. I am not sure if it is

advisable

> to give both nystatin and diflucan at the same time. Please

advise. I

> am really devastated that he has lost a lot of the tremendous

gains he

> made when he started diflucan.

> Thanks a lot

> Rohini

>

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Thanks, Cheryl and . I will plan on starting nystatin.

The diflucan I give is compounded at 10 mg/mL, and I give him 5 ml

once daily. How hgh can one go safely?

The nystatin is also compounded 2000,0000/ml and I am supposed to

give 5 ml thrice a day.

Do these doses look okay? Is it possible that the diflucan can stop

working after a month? I heard of this product called threelac.

Should I switch to that?

One thing I also notice is that whenever he falls sick with

cold/congestion, his behaviors get gets really bad...stimming,

emotional, irritable, mouthing and loss of focus. He is 4 yr old

with ASD and though he is verbal, his expressive speech is limited.

Any input will be helpful to me.

Thanks,

Rohini

> >

> > Hi,

> > I was wondering if any kids are on 2 antifungals

simulataneously?

> My 4

> > yr old was started on diflucan a month back. He immediately

showed

> > better focus and attention and was in his best behavior.

However,

> > since last week, he has started mouthing stuff again, being

> obsessive,

> > silly, giggling and his attention/focus has gone down again. He

> has

> > been a little sick with cough/cold but apart from that, I

haven't

> > changed anything else (oh, except that I fed him organic turkey

> breast

> > for the first time right around the time his behaviors changed).

> His

> > doctor had prescribed both diflucan and nystatin for him a month

> ago,

> > but I started with the diflucan only. I am not sure if it is

> advisable

> > to give both nystatin and diflucan at the same time. Please

> advise. I

> > am really devastated that he has lost a lot of the tremendous

> gains he

> > made when he started diflucan.

> > Thanks a lot

> > Rohini

> >

>

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Rohini hi,

Before I started I took threelac myself before giving it t my child. I

ended up inthe emergency room with UTI the first I ever got. I give 75mg of

diflucan TO MY 4YR old. I don't know if you use SSRI'S but every time I have

uped the dose I notice die-off. Serotonin I beieve increases the amount of

antifungals in the body. That's what I have observed.

Hope it helps.

Kavita

rohi_03 <rohi_03@...> wrote:

Thanks, Cheryl and . I will plan on starting nystatin.

The diflucan I give is compounded at 10 mg/mL, and I give him 5 ml

once daily. How hgh can one go safely?

The nystatin is also compounded 2000,0000/ml and I am supposed to

give 5 ml thrice a day.

Do these doses look okay? Is it possible that the diflucan can stop

working after a month? I heard of this product called threelac.

Should I switch to that?

One thing I also notice is that whenever he falls sick with

cold/congestion, his behaviors get gets really bad...stimming,

emotional, irritable, mouthing and loss of focus. He is 4 yr old

with ASD and though he is verbal, his expressive speech is limited.

Any input will be helpful to me.

Thanks,

Rohini

> >

> > Hi,

> > I was wondering if any kids are on 2 antifungals

simulataneously?

> My 4

> > yr old was started on diflucan a month back. He immediately

showed

> > better focus and attention and was in his best behavior.

However,

> > since last week, he has started mouthing stuff again, being

> obsessive,

> > silly, giggling and his attention/focus has gone down again. He

> has

> > been a little sick with cough/cold but apart from that, I

haven't

> > changed anything else (oh, except that I fed him organic turkey

> breast

> > for the first time right around the time his behaviors changed).

> His

> > doctor had prescribed both diflucan and nystatin for him a month

> ago,

> > but I started with the diflucan only. I am not sure if it is

> advisable

> > to give both nystatin and diflucan at the same time. Please

> advise. I

> > am really devastated that he has lost a lot of the tremendous

> gains he

> > made when he started diflucan.

> > Thanks a lot

> > Rohini

> >

>

---------------------------------

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I would bet that behavior is related to his illness. Hopefully once

he gets over the illness, he gets back to where he was. If not, I

would suspect another type of infection that is propelling his immune

system. (Side note: for us, I correlate certain behaviors with

bacterial infection.)

Hope this helps,

>

> Hi,

> I was wondering if any kids are on 2 antifungals simulataneously?

My 4

> yr old was started on diflucan a month back. He immediately showed

> better focus and attention and was in his best behavior. However,

> since last week, he has started mouthing stuff again, being

obsessive,

> silly, giggling and his attention/focus has gone down again. He has

> been a little sick with cough/cold but apart from that, I haven't

> changed anything else (oh, except that I fed him organic turkey

breast

> for the first time right around the time his behaviors changed).

His

> doctor had prescribed both diflucan and nystatin for him a month

ago,

> but I started with the diflucan only. I am not sure if it is

advisable

> to give both nystatin and diflucan at the same time. Please advise.

I

> am really devastated that he has lost a lot of the tremendous gains

he

> made when he started diflucan.

> Thanks a lot

> Rohini

>

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Hi Kavita,

No, I haven't started my son on any other medications like SSRIs. I

know that diflucan is a CYP2C9 inhibitor and could alter the plasma

concentrations of drugs that are metabolized through that enzyme

route.

Just curious - what SSRI are you using and what benefits did you see?

Thanks,

Rohini

> > >

> > > Hi,

> > > I was wondering if any kids are on 2 antifungals

> simulataneously?

> > My 4

> > > yr old was started on diflucan a month back. He immediately

> showed

> > > better focus and attention and was in his best behavior.

> However,

> > > since last week, he has started mouthing stuff again, being

> > obsessive,

> > > silly, giggling and his attention/focus has gone down again.

He

> > has

> > > been a little sick with cough/cold but apart from that, I

> haven't

> > > changed anything else (oh, except that I fed him organic

turkey

> > breast

> > > for the first time right around the time his behaviors

changed).

> > His

> > > doctor had prescribed both diflucan and nystatin for him a

month

> > ago,

> > > but I started with the diflucan only. I am not sure if it is

> > advisable

> > > to give both nystatin and diflucan at the same time. Please

> > advise. I

> > > am really devastated that he has lost a lot of the tremendous

> > gains he

> > > made when he started diflucan.

> > > Thanks a lot

> > > Rohini

> > >

> >

>

>

>

>

>

>

> ---------------------------------

> Be a better friend, newshound, and know-it-all with

Mobile. Try it now.

>

>

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Hi Rohini,

Your son seems to be very similar to mine,

I´d do a cormprehensive stool test at Genova Lab in search for other

infections, and do an A toxine for clostridium difficile and culture

and sensitive in reg lab if available. These were very revealing to

us, my son ended up with flagyl, erhitromicine and ketoconazole

altoghether.

I´d also check ASO and H.Pylori.

I think 50mg of diflucan is TOO low, if this is true, it may had

happened that in a beggining you lowered the yeast levels, but they

become a bit resistant, I´m not sure.

You may test alt/ast before raise dose and after 2 weeks you did it,

then every 45-60 days.

I think you can raise dose to 400mg before hepatic risk, please

check this.

hope this helped

> > >

> > > Hi,

> > > I was wondering if any kids are on 2 antifungals

> simulataneously?

> > My 4

> > > yr old was started on diflucan a month back. He immediately

> showed

> > > better focus and attention and was in his best behavior.

> However,

> > > since last week, he has started mouthing stuff again, being

> > obsessive,

> > > silly, giggling and his attention/focus has gone down again.

He

> > has

> > > been a little sick with cough/cold but apart from that, I

> haven't

> > > changed anything else (oh, except that I fed him organic

turkey

> > breast

> > > for the first time right around the time his behaviors

changed).

> > His

> > > doctor had prescribed both diflucan and nystatin for him a

month

> > ago,

> > > but I started with the diflucan only. I am not sure if it is

> > advisable

> > > to give both nystatin and diflucan at the same time. Please

> > advise. I

> > > am really devastated that he has lost a lot of the tremendous

> > gains he

> > > made when he started diflucan.

> > > Thanks a lot

> > > Rohini

> > >

> >

>

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Hi Kavita,

Very interesting, may you let me know a little bit more about your

SSRI experience,

drug, dose, other changes you´ve seen, sleep, bowel movements,

improvements, etc.

Thank you in advance.

>

> Rohini hi,

>

I don't know if you use SSRI'S but every time I have uped the dose I

notice die-off. Serotonin I beieve increases the amount of antifungals

in the body. That's what I have observed.

> Hope it helps.

> Kavita

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Hi Rohini and ,

The SSRI given depends on the child and your doc is the best guide. I would

suggest going thru the file section and read up on serotonin. So far I have seen

very good results with very small dosages. Kavita

Martín W <engranajes@...> wrote:

Hi Kavita,

Very interesting, may you let me know a little bit more about your

SSRI experience,

drug, dose, other changes you´ve seen, sleep, bowel movements,

improvements, etc.

Thank you in advance.

>

> Rohini hi,

>

I don't know if you use SSRI'S but every time I have uped the dose I

notice die-off. Serotonin I beieve increases the amount of antifungals

in the body. That's what I have observed.

> Hope it helps.

> Kavita

---------------------------------

Be a better friend, newshound, and know-it-all with Mobile. Try it now.

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