Elevated Homocysteine Found Again in Autistic Children

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Homocysteine level in urine of autistic and healthy children

Joanna Ka?uz.na-Czaplin'ska, Monika Michalska and Jacek Rynkowski

Acta Biochim Pol. 2011;58(1):31-4. Epub 2011 Mar 11.

[ Abstract + References ]

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Homocysteine is an amino acid which plays several important roles in

human physiology and is an important biomarker for possible deficiencies

of various vitamins (vitamin B6 and B12, folic acid). In this work GC-MS

method was used to determine the levels of homocysteine in the urine of

autistic and healthy children. The levels of homocysteine in urine

samples from 34 autistic and 21 healthy children were 2.36 ± 1.24 and

0.76 ± 0.31 (mmol?mol-1 creatinine), respectively. The higher level of

homocysteine in autistic children may indicate deficiencies of folic

acid and vitamins B6 and B12 in nutrition of these children. The results

of this work were taken into consideration in the nutrition of autistic

children treated in the Navicula Centre of Diagnosis and Therapy of

Autism in ?ódz' (Poland).

see also:

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