air pollution & hypomethylation: Epigenetic changes in elderly men after prolonged air pollution exposure - as in autism - wood smoke

[Guest guest]

* Epigenetic changes seen in elderly men after prolonged air

pollution exposure. <http://bit.ly/gZfU5n>

* 25 April 2011

Exposure to two kinds of air pollutants has been linked to

declines in a specific type of gene expression known to influence

the onset of chronic disease, report researchers in the journal

Environmental Health Perspectives. The six-month study of elderly

men in Boston found that DNA methylation was reduced after

exposures to higher levels of sulfates and black carbon.

* more... <http://bit.ly/gZfU5n>

Abnormal transmethylation/transsulfuration metabolism and DNA

hypomethylation among parents of children with autism.

<http://www.ncbi.nlm.nih.gov/pubmed/18512136>

SJ, Melnyk S, Jernigan S, Hubanks A, Rose S, Gaylor DW.

J Autism Dev Disord. 2008 Nov;38(10):1966-75.

Metabolic biomarkers of increased oxidative stress and impaired

methylation capacity in children with autism.

<http://www.ncbi.nlm.nih.gov/pubmed/15585776>

SJ, Cutler P, Melnyk S, Jernigan S, Janak L, Gaylor DW, Neubrander JA.

Am J Clin Nutr. 2004 Dec;80(6):1611-7.

DNA methylation, the early-life social environment and behavioral

disorders. <http://www.ncbi.nlm.nih.gov/pubmed/21484196>

Szyf M.

J Neurodev Disord. 2011 Mar 11.

Residential Proximity to Freeways and Autism in the CHARGE study.

<http://www.ncbi.nlm.nih.gov/pubmed/21156395>

Volk HE, Hertz-Picciotto I, Delwiche L, Lurmann F, McConnell R.

Environ Health Perspect. 2010 Dec 13.

States get tough on outdoor wood furnace smoke

By LISA RATHKE Associated Press Writer

04/04/2010 01:03:24 PM EDT

http://www.ydr.com/ci_14818697

*

Where there's smoke, there's trouble. <http://bit.ly/gGImJB>

Where there is wood smoke, there is fire - as well as invisible

toxins you could be inhaling. A little soot exposure probably

isn't harmful to most people, pulmonologists say, but a new

Danish-led study suggests regular exposure could damage DNA.

~Burlington County Times, Pennsylvania

Smoke from wood fireplaces, stoves raises new health concerns.

<http://www.environmentalhealthnews.org/ehs/news/hazards-of-wood-smoke>

By Cheryl Katz Environmental Health News 14 March 2011

Smoke curling from the chimney of the Clair Tappaan Lodge is a welcome

sight to chilly snowshoers and cross-country skiers in California's

Sierra Nevada. Guests at this landmark Sierra Club hostel relax in the

warmth and aroma of the crackling log fire.

Those same woodsy scents waft across the north, as millions of

fireplaces and wood stoves are lit by people seeking an environmentally

friendly heating source. But recent research raises concerns over the

toxic substances in wood smoke. Scientists say the tiny airborne specks

of pollution carry carcinogenic chemicals deep into lungs and trigger

DNA damage and gene changes comparable to the hazards of cigarette smoke

and car exhaust.