Dr. McCandless' Low natural killer cell cytotoxic activity in autism study

[Guest guest]

Dr. McCandless,

Stop Calling It Autism! launched a medical disease registry almost two months

ago and we are already noticing something that was studied in one of the studies

you have been part of. We have been noticing that a surprisingly high number of

children with autism have either a low absolute NK Cell count or have decreased

Decreased NK Cell cytotoxicity. One very important detail is that Natural

Killer (NK) cells, are a very important component of the cell-mediated arm of

the immune system.

Based on the CDC's Vaccination of Persons with Primary and Secondary Immune

Deficiencies document, children suffering from primary immune deficiencies

(including the cell mediated category) should not receive live vaccines due to

the risk of acquiring the disease from the vaccine strains. Live vaccine

includes MMR, MMRV, OPV, LAIV, yellow fever, varicella, zoster, rotavirus, and

vaccinia (smallpox).

I am curious to know if you and the other 14 doctors and medical researchers

discuss the relationship between cell-mediated immune defects and the clear

contraindications that this is for many live vaccines. Live vaccine includes

MMR, MMRV, OPV, LAIV, yellow fever, varicella, zoster, rotavirus, and vaccinia

(smallpox).

Wouldn't it be common sense and imperative to order a comprehensive immune

system workup as the one being used in the SCIA's Medical Disease Registry prior

to administering these vaccinations to children?

Low natural killer cell cytotoxic activity in autism: the role of glutathione,

IL-2 and IL-15.

http://www.ncbi.nlm.nih.gov/pubmed/18929414

Vojdani A, Mumper E, Granpeesheh D, Mielke L, Traver D, Bock K, Hirani K,

Neubrander J, Woeller KN, O'Hara N, Usman A, Schneider C, Hebroni F, Berookhim

J, McCandless J.

Natural Killer Cell Functional Assay, FC

http://www.questdiagnostics.com/hcp/testmenu/jsp/showTestMenu.jsp?fn=34184X.html\

& labCode=QDV

Natural Killer (NK) cells, a component of the cell-mediated arm of the immune

system, mediate destruction of some types of tumor cells and virus-infected

cells. Decreased NK cytotoxicity is associated with impaired immune

surveillance, and may explain a predisposition to malignancies and viral

infections.

Vaccination of Persons with Primary and Secondary Immune Deficiencies

http://www.cdc.gov/vaccines/pubs/pinkbook/downloads/appendices/A/immuno-table.pd\

f

Thanks,

Founder and Director of Stop Calling It Autism!

http://www.stopcallingitautism.org