Guest guest Posted April 9, 2012 Report Share Posted April 9, 2012 Pollutants are associated with metabolic conditions (references hereinbelow) thus the findings of Krakowiaket al maybe a further reflection of pollutants as etiologically significant factors in many and perhaps most cases of autism and also a further indictment of so-called risk-management policies enforced to allow " low dose " exposures to myriad molecules which are profitably patented. // Maternal Metabolic Conditions and Risk for Autism and Other Neurodevelopmental Disorders * a Krakowiak, et al Pediatrics peds.2011-2583; published ahead of print April 9, 2012, doi:10.1542/peds.2011-2583 * Abstract <http://pediatrics.aappublications.org/content/early/2012/04/04/peds.2011-2583.a\ bstract?sid=857c12f8-cd6d-4898-a87f-610dcf50996e> * Full Text (PDF) <http://pediatrics.aappublications.org/content/early/2012/04/04/peds.2011-2583.f\ ull.pdf+html?sid=857c12f8-cd6d-4898-a87f-610dcf50996e> OBJECTIVE: We examined whether metabolic conditions (MCs) during pregnancy (diabetes, hypertension, and obesity) are associated with autism spectrum disorder (ASD), developmental delays (DD), or impairments in specific domains of development in the offspring.... CONCLUSIONS: Maternal MCs may be broadly associated with neurodevelopmental problems in children. With obesity rising steadily, these results appear to raise serious public health concerns. */References/* [just a small sampling] Relationship between serum concentrations of persistent organic pollutants and the prevalence of metabolic syndrome among non-diabetic adults: results from the National Health and Nutrition Examination Survey 1999-2002. <http://www.ncbi.nlm.nih.gov/pubmed/17624515> Lee DH, Lee IK, Porta M, Steffes M, s DR Jr. Diabetologia. 2007 Sep;50(9):1841-51. Persistent organic pollutants and obesity-related metabolic dysfunction: focusing on type 2 diabetes. <http://www.ncbi.nlm.nih.gov/pubmed/22323980> Lee DH. Epidemiol Health. 2012;34:e2012002. Obesity and persistent organic pollutants: possible obesogenic effect of organochlorine pesticides and polychlorinated biphenyls. <http://www.ncbi.nlm.nih.gov/pubmed/20559302> Dirinck E, Jorens PG, Covaci A, Geens T, Roosens L, Neels H, Mertens I, Van Gaal L. Obesity (Silver Spring). 2011 Apr;19(4):709-14. Do interactions between gut ecology and environmental chemicals contribute to obesity and diabetes? <http://www.ncbi.nlm.nih.gov/pubmed/22042266> Snedeker SM, Hay AG. Environ Health Perspect. 2012 Mar;120(3):332-9. Mitochondrial dysfunction and insulin resistance: the contribution of dioxin-like substances. <http://www.ncbi.nlm.nih.gov/pubmed/21785739> Lee HK. Diabetes Metab J. 2011 Jun;35(3):207-15. Increase in metabolic syndrome-related hospitalizations in relation to environmental sources of persistent organic pollutants. <http://www.ncbi.nlm.nih.gov/pubmed/21556177> Sergeev AV, Carpenter DO. Int J Environ Res Public Health. 2011 Mar;8(3):762-76. Low dose organochlorine pesticides and polychlorinated biphenyls predict obesity, dyslipidemia, and insulin resistance among people free of diabetes. <http://www.ncbi.nlm.nih.gov/pubmed/21298090> Lee DH, Steffes MW, Sjödin A, RS, Needham LL, s DR Jr. PLoS One. 2011 Jan 26;6(1):e15977. Association of low-dose exposure to persistent organic pollutants with global DNA hypomethylation in healthy Koreans. <http://www.ncbi.nlm.nih.gov/pubmed/20064773> Kim KY, Kim DS, Lee SK, Lee IK, Kang JH, Chang YS, s DR, Steffes M, Lee DH. Environ Health Perspect. 2010 Mar;118(3):370-4. Quote Link to comment Share on other sites More sharing options...
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