Re: Economist article on CFS (or ME)

[Guest guest]

Jil

According to Dr G and Dr N Klimas (A speaker at the

conference ths week) a CFS research that there are

many very close relationships between CFS and Autism.

I have heard it discussed that the primary difference

is the time of onset. CFS post developement and Autism

at or shortly after birth prior to developement.

The Biomedical treatments are similar as well.

Bill

--- Jill Boyer <sjillboyer@...> wrote:

> Below is an article from the Economist. I follow ME

> very closely since there are three female adult

> relatives in my children's family (one on their

> father's side and two on mine) with this. I am very

> curious if there are any connections with the genes

> in this study to CFS and autism.

>

>

http://www.economist.com/science/displaystory.cfm?story_id=11326174

>

> ME is a puzzling illness, but it appears to have a

> biological basis and a test for it could be

> developed

> A DISEASE that carries with it a social stigma

> causes additional and unnecessary suffering. This

> has often been so with myalgic encephalomyelitis

> (ME), or chronic-fatigue syndrome, as it is also

> known. Despite debilitating symptoms, patients have

> been accused of suffering from an imaginary illness:

> “yuppie flu”. Doctors have struggled to distinguish

> the ailing from the malingering. Nonetheless,

> evidence has grown in recent years that the syndrome

> is real, and now there is news that it has its roots

> in genetics.

> ME manifests as extreme exhaustion, something that

> may include a range of other symptoms, such as

> disturbed sleep, difficulties in remembering and

> concentrating, headaches, and painful muscles and

> joints. Psychological symptoms, such as anxiety and

> irritability, can also be present. As the symptoms

> can vary in severity, the syndrome can be hard to

> identify, and patients can suffer for months before

> a diagnosis is made.

> However, new hope for ME sufferers arrived this

> week at a conference in Cambridge, in Britain. The

> event, organised by ME Research UK and the Irish ME

> Trust, two charities that help to fund studies and

> assist sufferers, was attended by researchers

> investigating what causes the illness and how it

> could be treated.

> Kerr of St 's University of London

> told the meeting that with his colleagues they have

> identified 88 genes which are expressed differently

> in the blood of patients who had been diagnosed with

> ME. Moreover, in studying the records of 55 patients

> with ME, they found that they could divide them into

> seven separate sub-types that consistently pair

> distinct genetic patterns with a combination and

> severity of patients' symptoms. This, says Dr Kerr,

> points to a biological basis for the illness and

> holds out hope that a blood test could be developed

> to identify its different forms. His group are now

> trying to find the biological markers that such a

> blood test would need to detect.

>

> ME, myself, why?

> One tactic for dealing with ME is to treat its

> symptoms with drugs that are already used against

> other diseases. Patients with some of the severest

> symptoms suffer from low blood pressure and have

> difficulty regulating their heartbeat. Newton,

> of Newcastle University in Britain, says this is

> because of problems with their autonomic nervous

> systems, which is responsible for subconscious

> activities. In studies using a magnetic-resonance

> imaging scanner, she found a build-up of acid in the

> muscles of ME patients when they took exercise. This

> can cause muscle weakness and pain. Dr Newton

> believes the build-up could be influenced entirely,

> or at least in part, by the degree to which the

> autonomic nervous system fails to properly maintain

> blood flow. It could also mean that drugs that

> already exist to help improve blood flow might also

> help some ME patients.

> But what triggers ME? Some estimates put its

> occurrence at around one in 200 people in America

> and Britain. Sufferers are often in their 20s and

> 30s, and more women are affected than men. That it

> is so widespread suggests to some researchers that

> there are many causes, including exposure to certain

> viruses and other infectious diseases.

> A long period of fatigue after suffering from an

> infectious disease is not unusual. At the

> conference, a team of Australian researchers

> speculated that many cases of ME are in fact cases

> of “post-infectious chronic fatigue”.

> Graves, of the Australian Rickettsial Reference

> Laboratory, said they had found a proportion of

> Australian ME sufferers may have a genetic

> predisposition to developing ME as a result of

> exposure to Q Fever or Flinders Island Spotted

> Fever. These are a pair of relatively uncommon

> diseases caused by two bacteria which can pass

> between animals and humans. If their hypothesis is

> correct, Dr Graves believes the incidence of ME in

> Australia may be reduced by greater public-health

> measures.

> Although the trigger for most cases of ME may

> remain a mystery, the discovery of its biological

> roots and the promise of a test will bring hope of a

> diagnosis to sufferers. And, perhaps, inspire a

> sudden recovery in the malingerers.

>

>

>

>

>

> ---------------------------------

> Be a better friend, newshound, and know-it-all with

> Mobile. Try it now.

>

> [Non-text portions of this message have been

> removed]

>

>

________________________________________________________________________________\

____

Be a better friend, newshound, and

know-it-all with Mobile. Try it now.

http://mobile./;_ylt=Ahu06i62sR8HDtDypao8Wcj9tAcJ

[Guest guest]

Thanks Bill. Yes, I have two children with autism and as I said, several female

relatives with ME. Ironically, I am very close to my sister-in-law (the sister

of my children's father) than my own relatives and I witnessed the major change

in my sister-in-law right in front of my eyes. I started reading books on ME

before my children were even born. When I discovered that my aunt and her cousin

both had ME as well, I couldn't help but wonder about the connection. That is

why I turned to . I am very excited about the genetic research in both ME

and autism. As you can see, the research has shifted from DNA analysis to

genetic expression in both ME and autism. I really think that this will confirm

the connection between the two.

All the best,

Jill

---------------------------------

Be a better friend, newshound, and know-it-all with Mobile. Try it now.

[Guest guest]

Hi Bill-

Did you go to the conference? Can you refer me to

where I can read about what they discussed?

Thanks!

--- Bill klimas <klimas_bill@...> wrote:

> Jil

> According to Dr G and Dr N Klimas (A speaker at the

> conference ths week) a CFS research that there are

> many very close relationships between CFS and

> Autism.

> I have heard it discussed that the primary

> difference

> is the time of onset. CFS post developement and

> Autism

> at or shortly after birth prior to developement.

>

> The Biomedical treatments are similar as well.

>

> Bill

>

> --- Jill Boyer <sjillboyer@...> wrote:

>

> > Below is an article from the Economist. I follow

> ME

> > very closely since there are three female adult

> > relatives in my children's family (one on their

> > father's side and two on mine) with this. I am

> very

> > curious if there are any connections with the

> genes

> > in this study to CFS and autism.

> >

> >

>

http://www.economist.com/science/displaystory.cfm?story_id=11326174

> >

> > ME is a puzzling illness, but it appears to have a

> > biological basis and a test for it could be

> > developed

> > A DISEASE that carries with it a social stigma

> > causes additional and unnecessary suffering. This

> > has often been so with myalgic encephalomyelitis

> > (ME), or chronic-fatigue syndrome, as it is also

> > known. Despite debilitating symptoms, patients

> have

> > been accused of suffering from an imaginary

> illness:

> > “yuppie flu”. Doctors have struggled to

> distinguish

> > the ailing from the malingering. Nonetheless,

> > evidence has grown in recent years that the

> syndrome

> > is real, and now there is news that it has its

> roots

> > in genetics.

> > ME manifests as extreme exhaustion, something

> that

> > may include a range of other symptoms, such as

> > disturbed sleep, difficulties in remembering and

> > concentrating, headaches, and painful muscles and

> > joints. Psychological symptoms, such as anxiety

> and

> > irritability, can also be present. As the symptoms

> > can vary in severity, the syndrome can be hard to

> > identify, and patients can suffer for months

> before

> > a diagnosis is made.

> > However, new hope for ME sufferers arrived this

> > week at a conference in Cambridge, in Britain. The

> > event, organised by ME Research UK and the Irish

> ME

> > Trust, two charities that help to fund studies and

> > assist sufferers, was attended by researchers

> > investigating what causes the illness and how it

> > could be treated.

> > Kerr of St 's University of

> London

> > told the meeting that with his colleagues they

> have

> > identified 88 genes which are expressed

> differently

> > in the blood of patients who had been diagnosed

> with

> > ME. Moreover, in studying the records of 55

> patients

> > with ME, they found that they could divide them

> into

> > seven separate sub-types that consistently pair

> > distinct genetic patterns with a combination and

> > severity of patients' symptoms. This, says Dr

> Kerr,

> > points to a biological basis for the illness and

> > holds out hope that a blood test could be

> developed

> > to identify its different forms. His group are now

> > trying to find the biological markers that such a

> > blood test would need to detect.

> >

> > ME, myself, why?

> > One tactic for dealing with ME is to treat its

> > symptoms with drugs that are already used against

> > other diseases. Patients with some of the severest

> > symptoms suffer from low blood pressure and have

> > difficulty regulating their heartbeat.

> Newton,

> > of Newcastle University in Britain, says this is

> > because of problems with their autonomic nervous

> > systems, which is responsible for subconscious

> > activities. In studies using a magnetic-resonance

> > imaging scanner, she found a build-up of acid in

> the

> > muscles of ME patients when they took exercise.

> This

> > can cause muscle weakness and pain. Dr Newton

> > believes the build-up could be influenced

> entirely,

> > or at least in part, by the degree to which the

> > autonomic nervous system fails to properly

> maintain

> > blood flow. It could also mean that drugs that

> > already exist to help improve blood flow might

> also

> > help some ME patients.

> > But what triggers ME? Some estimates put its

> > occurrence at around one in 200 people in America

> > and Britain. Sufferers are often in their 20s and

> > 30s, and more women are affected than men. That it

> > is so widespread suggests to some researchers that

> > there are many causes, including exposure to

> certain

> > viruses and other infectious diseases.

> > A long period of fatigue after suffering from an

> > infectious disease is not unusual. At the

> > conference, a team of Australian researchers

> > speculated that many cases of ME are in fact cases

> > of “post-infectious chronic fatigue”.

> > Graves, of the Australian Rickettsial Reference

> > Laboratory, said they had found a proportion of

> > Australian ME sufferers may have a genetic

> > predisposition to developing ME as a result of

> > exposure to Q Fever or Flinders Island Spotted

> > Fever. These are a pair of relatively uncommon

> > diseases caused by two bacteria which can pass

> > between animals and humans. If their hypothesis is

> > correct, Dr Graves believes the incidence of ME in

> > Australia may be reduced by greater public-health

> > measures.

> > Although the trigger for most cases of ME may

> > remain a mystery, the discovery of its biological

> > roots and the promise of a test will bring hope of

> a

> > diagnosis to sufferers. And, perhaps, inspire a

> > sudden recovery in the malingerers.

> >

> >

> >

> >

> >

> > ---------------------------------

> > Be a better friend, newshound, and know-it-all

> with

> > Mobile. Try it now.

> >

> > [Non-text portions of this message have been

> > removed]

> >

> >

>

>

>

>

>

________________________________________________________________________________\

____

> Be a better friend, newshound, and

> know-it-all with Mobile. Try it now.

>

http://mobile./;_ylt=Ahu06i62sR8HDtDypao8Wcj9tAcJ

>

________________________________________________________________________________\

____

Be a better friend, newshound, and

know-it-all with Mobile. Try it now.

http://mobile./;_ylt=Ahu06i62sR8HDtDypao8Wcj9tAcJ

[Guest guest]

No I did not go but K was the opening speaker.

She arrived back over the weekend and I have yet to

speak with her. I will touch bases and get back to you

on the conference's agenda.

Bill

--- <thecolemans4@...> wrote:

> Hi Bill-

> Did you go to the conference? Can you refer me to

> where I can read about what they discussed?

> Thanks!

>

>

>

> --- Bill klimas <klimas_bill@...> wrote:

>

> > Jil

> > According to Dr G and Dr N Klimas (A speaker at

> the

> > conference ths week) a CFS research that there are

> > many very close relationships between CFS and

> > Autism.

> > I have heard it discussed that the primary

> > difference

> > is the time of onset. CFS post developement and

> > Autism

> > at or shortly after birth prior to developement.

> >

> > The Biomedical treatments are similar as well.

> >

> > Bill

> >

> > --- Jill Boyer <sjillboyer@...> wrote:

> >

> > > Below is an article from the Economist. I follow

> > ME

> > > very closely since there are three female adult

> > > relatives in my children's family (one on their

> > > father's side and two on mine) with this. I am

> > very

> > > curious if there are any connections with the

> > genes

> > > in this study to CFS and autism.

> > >

> > >

> >

>

http://www.economist.com/science/displaystory.cfm?story_id=11326174

> > >

> > > ME is a puzzling illness, but it appears to have

> a

> > > biological basis and a test for it could be

> > > developed

> > > A DISEASE that carries with it a social

> stigma

> > > causes additional and unnecessary suffering.

> This

> > > has often been so with myalgic encephalomyelitis

> > > (ME), or chronic-fatigue syndrome, as it is also

> > > known. Despite debilitating symptoms, patients

> > have

> > > been accused of suffering from an imaginary

> > illness:

> > > “yuppie flu”. Doctors have struggled to

> > distinguish

> > > the ailing from the malingering. Nonetheless,

> > > evidence has grown in recent years that the

> > syndrome

> > > is real, and now there is news that it has its

> > roots

> > > in genetics.

> > > ME manifests as extreme exhaustion, something

> > that

> > > may include a range of other symptoms, such as

> > > disturbed sleep, difficulties in remembering and

> > > concentrating, headaches, and painful muscles

> and

> > > joints. Psychological symptoms, such as anxiety

> > and

> > > irritability, can also be present. As the

> symptoms

> > > can vary in severity, the syndrome can be hard

> to

> > > identify, and patients can suffer for months

> > before

> > > a diagnosis is made.

> > > However, new hope for ME sufferers arrived

> this

> > > week at a conference in Cambridge, in Britain.

> The

> > > event, organised by ME Research UK and the Irish

> > ME

> > > Trust, two charities that help to fund studies

> and

> > > assist sufferers, was attended by researchers

> > > investigating what causes the illness and how it

> > > could be treated.

> > > Kerr of St 's University of

> > London

> > > told the meeting that with his colleagues they

> > have

> > > identified 88 genes which are expressed

> > differently

> > > in the blood of patients who had been diagnosed

> > with

> > > ME. Moreover, in studying the records of 55

> > patients

> > > with ME, they found that they could divide them

> > into

> > > seven separate sub-types that consistently pair

> > > distinct genetic patterns with a combination and

> > > severity of patients' symptoms. This, says Dr

> > Kerr,

> > > points to a biological basis for the illness and

> > > holds out hope that a blood test could be

> > developed

> > > to identify its different forms. His group are

> now

> > > trying to find the biological markers that such

> a

> > > blood test would need to detect.

> > >

> > > ME, myself, why?

> > > One tactic for dealing with ME is to treat its

> > > symptoms with drugs that are already used

> against

> > > other diseases. Patients with some of the

> severest

> > > symptoms suffer from low blood pressure and have

> > > difficulty regulating their heartbeat.

> > Newton,

> > > of Newcastle University in Britain, says this is

> > > because of problems with their autonomic nervous

> > > systems, which is responsible for subconscious

> > > activities. In studies using a

> magnetic-resonance

> > > imaging scanner, she found a build-up of acid in

> > the

> > > muscles of ME patients when they took exercise.

> > This

> > > can cause muscle weakness and pain. Dr Newton

> > > believes the build-up could be influenced

> > entirely,

> > > or at least in part, by the degree to which the

> > > autonomic nervous system fails to properly

> > maintain

> > > blood flow. It could also mean that drugs that

> > > already exist to help improve blood flow might

> > also

> > > help some ME patients.

> > > But what triggers ME? Some estimates put its

> > > occurrence at around one in 200 people in

> America

> > > and Britain. Sufferers are often in their 20s

> and

> > > 30s, and more women are affected than men. That

> it

> > > is so widespread suggests to some researchers

> that

> > > there are many causes, including exposure to

> > certain

> > > viruses and other infectious diseases.

> > > A long period of fatigue after suffering from

> an

> > > infectious disease is not unusual. At the

> > > conference, a team of Australian researchers

> > > speculated that many cases of ME are in fact

> cases

> > > of “post-infectious chronic fatigue”.

> > > Graves, of the Australian Rickettsial Reference

> > > Laboratory, said they had found a proportion of

> > > Australian ME sufferers may have a genetic

> > > predisposition to developing ME as a result of

> > > exposure to Q Fever or Flinders Island Spotted

> > > Fever. These are a pair of relatively uncommon

> > > diseases caused by two bacteria which can pass

> > > between animals and humans. If their hypothesis

> is

> > > correct, Dr Graves believes the incidence of ME

> in

> > > Australia may be reduced by greater

> public-health

> > > measures.

> > > Although the trigger for most cases of ME may

> > > remain a mystery, the discovery of its

> biological

> > > roots and the promise of a test will bring hope

> of

> > a

> > > diagnosis to sufferers. And, perhaps, inspire a

> > > sudden recovery in the malingerers.

> > >

> > >

> > >

> > >

> > >

> > > ---------------------------------

> > > Be a better friend, newshound, and know-it-all

> > with

> > > Mobile. Try it now.

> > >

> > > [Non-text portions of this message have been

> > > removed]

> > >

> > >

> >

> >

> >

> >

>

=== message truncated ===

[Guest guest]

Cythia

Here are a couple of links to articles I turned up.

www.phgfoundation.org/news/4196

www.cfs.purdue.edu/fn/Conference2008.shtml

www.innovations-report.de/html/berichte/medizin_gesundheit/bericht-109477.html

http://ukpress.google.com/article/ALeqM5gdXe02VV_kO3IBpYP-zcny_3S6mw

--- <thecolemans4@...> wrote:

> Hi Bill-

> Did you go to the conference? Can you refer me to

> where I can read about what they discussed?

> Thanks!

>

>

>

> --- Bill klimas <klimas_bill@...> wrote:

>

> > Jil

> > According to Dr G and Dr N Klimas (A speaker at

> the

> > conference ths week) a CFS research that there are

> > many very close relationships between CFS and

> > Autism.

> > I have heard it discussed that the primary

> > difference

> > is the time of onset. CFS post developement and

> > Autism

> > at or shortly after birth prior to developement.

> >

> > The Biomedical treatments are similar as well.

> >

> > Bill

> >

> > --- Jill Boyer <sjillboyer@...> wrote:

> >

> > > Below is an article from the Economist. I follow

> > ME

> > > very closely since there are three female adult

> > > relatives in my children's family (one on their

> > > father's side and two on mine) with this. I am

> > very

> > > curious if there are any connections with the

> > genes

> > > in this study to CFS and autism.

> > >

> > >

> >

>

http://www.economist.com/science/displaystory.cfm?story_id=11326174

> > >

> > > ME is a puzzling illness, but it appears to have

> a

> > > biological basis and a test for it could be

> > > developed

> > > A DISEASE that carries with it a social

> stigma

> > > causes additional and unnecessary suffering.

> This

> > > has often been so with myalgic encephalomyelitis

> > > (ME), or chronic-fatigue syndrome, as it is also

> > > known. Despite debilitating symptoms, patients

> > have

> > > been accused of suffering from an imaginary

> > illness:

> > > “yuppie flu”. Doctors have struggled to

> > distinguish

> > > the ailing from the malingering. Nonetheless,

> > > evidence has grown in recent years that the

> > syndrome

> > > is real, and now there is news that it has its

> > roots

> > > in genetics.

> > > ME manifests as extreme exhaustion, something

> > that

> > > may include a range of other symptoms, such as

> > > disturbed sleep, difficulties in remembering and

> > > concentrating, headaches, and painful muscles

> and

> > > joints. Psychological symptoms, such as anxiety

> > and

> > > irritability, can also be present. As the

> symptoms

> > > can vary in severity, the syndrome can be hard

> to

> > > identify, and patients can suffer for months

> > before

> > > a diagnosis is made.

> > > However, new hope for ME sufferers arrived

> this

> > > week at a conference in Cambridge, in Britain.

> The

> > > event, organised by ME Research UK and the Irish

> > ME

> > > Trust, two charities that help to fund studies

> and

> > > assist sufferers, was attended by researchers

> > > investigating what causes the illness and how it

> > > could be treated.

> > > Kerr of St 's University of

> > London

> > > told the meeting that with his colleagues they

> > have

> > > identified 88 genes which are expressed

> > differently

> > > in the blood of patients who had been diagnosed

> > with

> > > ME. Moreover, in studying the records of 55

> > patients

> > > with ME, they found that they could divide them

> > into

> > > seven separate sub-types that consistently pair

> > > distinct genetic patterns with a combination and

> > > severity of patients' symptoms. This, says Dr

> > Kerr,

> > > points to a biological basis for the illness and

> > > holds out hope that a blood test could be

> > developed

> > > to identify its different forms. His group are

> now

> > > trying to find the biological markers that such

> a

> > > blood test would need to detect.

> > >

> > > ME, myself, why?

> > > One tactic for dealing with ME is to treat its

> > > symptoms with drugs that are already used

> against

> > > other diseases. Patients with some of the

> severest

> > > symptoms suffer from low blood pressure and have

> > > difficulty regulating their heartbeat.

> > Newton,

> > > of Newcastle University in Britain, says this is

> > > because of problems with their autonomic nervous

> > > systems, which is responsible for subconscious

> > > activities. In studies using a

> magnetic-resonance

> > > imaging scanner, she found a build-up of acid in

> > the

> > > muscles of ME patients when they took exercise.

> > This

> > > can cause muscle weakness and pain. Dr Newton

> > > believes the build-up could be influenced

> > entirely,

> > > or at least in part, by the degree to which the

> > > autonomic nervous system fails to properly

> > maintain

> > > blood flow. It could also mean that drugs that

> > > already exist to help improve blood flow might

> > also

> > > help some ME patients.

> > > But what triggers ME? Some estimates put its

> > > occurrence at around one in 200 people in

> America

> > > and Britain. Sufferers are often in their 20s

> and

> > > 30s, and more women are affected than men. That

> it

> > > is so widespread suggests to some researchers

> that

> > > there are many causes, including exposure to

> > certain

> > > viruses and other infectious diseases.

> > > A long period of fatigue after suffering from

> an

> > > infectious disease is not unusual. At the

> > > conference, a team of Australian researchers

> > > speculated that many cases of ME are in fact

> cases

> > > of “post-infectious chronic fatigue”.

> > > Graves, of the Australian Rickettsial Reference

> > > Laboratory, said they had found a proportion of

> > > Australian ME sufferers may have a genetic

> > > predisposition to developing ME as a result of

> > > exposure to Q Fever or Flinders Island Spotted

> > > Fever. These are a pair of relatively uncommon

> > > diseases caused by two bacteria which can pass

> > > between animals and humans. If their hypothesis

> is

> > > correct, Dr Graves believes the incidence of ME

> in

> > > Australia may be reduced by greater

> public-health

> > > measures.

> > > Although the trigger for most cases of ME may

> > > remain a mystery, the discovery of its

> biological

> > > roots and the promise of a test will bring hope

> of

> > a

> > > diagnosis to sufferers. And, perhaps, inspire a

> > > sudden recovery in the malingerers.

> > >

> > >

> > >

> > >

> > >

> > > ---------------------------------

> > > Be a better friend, newshound, and know-it-all

> > with

> > > Mobile. Try it now.

> > >

> > > [Non-text portions of this message have been

> > > removed]

> > >

> > >

> >

> >

> >

> >

>

=== message truncated ===

[Guest guest]

Years ago a spent a week in Dr. Goldberg's office learning the protocol. The

first two days an Internal Medicine resident and I did nothing but look at

lab work. He said that the lab work of children with autism looked like the lab

work of adults with CFS.

E. on RN, MSN

**************Wondering what's for Dinner Tonight? Get new twists on family

favorites at AOL Food.

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