Re: Go for anti-virals/IVIG/or not?

April 27, 2008

These results are different from my son's so i would not want to

guess and be wrong. My son had high HHV6 CMV and EBV. He also had

high Immune Panel markers....CD4, CD8, CD16, CD56.

My son has never had a high ASO, but has responded very well to long

term antibiotic treatment and gamma globulin (in the muscle not the

vein).

I could be wrong, but the fact that your son has high IGG to measles

and mumps and rubella could be indicative of overactive immune system

as his body has recently tried to fight off these illness. It is not

uncommon for HHV6 to be low, it is hiding.

Hopefully others will see your post and help decipher, many posters

are very good at this.

What does his doctor say of these results?

>

> I am relatively new to the group and have been reading up the

archives

> since I joined to educate myself further. I apologize for the

length of

> this email, but I am feeling quite lost in our treatment path to

heal my

> son who has a diagnosis of autism. I would really appreciate any

> guidance from the group.

>

> My 3.8 yr old son has been largely a non-responder to the few

> bio-medical treatments tried to-date. I wanted to evaluate whether

it

> would make sense for us to next try anti-viral or IVIG or

treatment

> for him, and recently got back his blood IgG and viral titers test

> results from Quest Diagnostics.

>

> I feel like I am missing something to explain the contradiction in

test

> results vs his symptoms. My son had multiple ear infections, easily

> catches colds, has chronic swollen tonsils, and shows gamma strep

in his

> stool but his blood test results below seem to suggest that he does

not

> have PANDAS markers, most of his immunoglobulins except for IgG4

are in

> range, no major viral titer markers, and no crazily high vaccine

titers

> (in fact, he has no antibody to polio and pertussis even though he

was

> vaccinated).

>

> - Should anti-viral treatments be a priority for us?

> - What about relative priority for IVIG treatment? Does the elevated

> IgG4 simply indicate food allergies or something else?

> - Are there instances where kids have stealth viruses that don't

show up

> in these test results?

>

> Below are the results

> --------------------------------------------------------------------

----\

> -------------------------------

>

> Immunoglobulins (Ref range in brackets)

> IgE: 58 (< 72)

> IgD: 2 (<179)

> IgM: 116 (26-218)

> IgA: 111 (24-121)

>

> IgG: 929 (533-1078)

> IgG1: 594 (315-945)

> IgG2: 136 (38-225)

> IgG3: 52 (17-68)

> **IgG4: 61.7 (1-54)

>

> Vaccine titers (Fully vaccinated, with the exception of Varicella)

>

> Measles IgG: 2.45 (> 1.10 = positive) -- are these very high?

> Mumps IgG: 2.93 (> 1.10 = positive) -- are these very high?

> Rubella IgG: 4.49 (> 1.10 = antibody detected) -- are these very

high?

> Hepatitis B surface antibody: Reactive

> Varicella Zoster IgG: 2.64 (> 1.10 = positive)

> HiB: 1.55 (> 1.0 = protective level)

> Diphtheria Antitoxoid: 0.23 (> 0.01 = protective level)

> Tetanus Antitoxoid: 1.00 (>0.15 = protective level)

> Pertussis IgG: 3 (< 40)

> Polio I, II, III Antibodies: <1:8 (antibody not detected)

>

> Viral titers (< 0.90 = No antibody detected for all results below)

>

> Cytomegalovirus IgG: < 0.90

> Cytomegalovirus IgM: 0.59

> Herpes Simplex - 1 IgG: 0.06

> Herpes Simplex - 2 IgG: 0.06

> HHV6 DNA, PCR: Not detected

> Parvovirus B-19 IgG: 0.3

> Epstein-Barr Virus-VCA IgG: 0.12

> Epstein-Barr Virus-Nuclear IgG: 0.52

>

> Strep/PANDAS (Ref range in brackets)

> ASO: 7 (<150)

> Anti-DNASE-B: < 60 (Preschool: <=60 titer)

> --------------------------------------------------------------------

----\

> --------------------------

> Really sorry for the long email and the number of questions, but I

am

> unable to figure this out..

>

> Any pointers would be super helpful.

>

> Sarita

>

April 27, 2008

What are his total IgG/ IgA/ and all subclasses, this is what you need to run. I

would ask to do these tests. you can ask a DAN doc or your pediatrician. I

personall would follow ...we have been very successful with this treatment.

hope this helps, Noel

myasdprofile <asdmommy@...> wrote:

I am relatively new to the group and have been reading up the archives

since I joined to educate myself further. I apologize for the length of

this email, but I am feeling quite lost in our treatment path to heal my

son who has a diagnosis of autism. I would really appreciate any

guidance from the group.

My 3.8 yr old son has been largely a non-responder to the few

bio-medical treatments tried to-date. I wanted to evaluate whether it

would make sense for us to next try anti-viral or IVIG or treatment

for him, and recently got back his blood IgG and viral titers test

results from Quest Diagnostics.

I feel like I am missing something to explain the contradiction in test

results vs his symptoms. My son had multiple ear infections, easily

catches colds, has chronic swollen tonsils, and shows gamma strep in his

stool but his blood test results below seem to suggest that he does not

have PANDAS markers, most of his immunoglobulins except for IgG4 are in

range, no major viral titer markers, and no crazily high vaccine titers

(in fact, he has no antibody to polio and pertussis even though he was

vaccinated).

- Should anti-viral treatments be a priority for us?

- What about relative priority for IVIG treatment? Does the elevated

IgG4 simply indicate food allergies or something else?

- Are there instances where kids have stealth viruses that don't show up

in these test results?

Below are the results

----------------------------------------------------------\

-------------------------------

Immunoglobulins (Ref range in brackets)

IgE: 58 (< 72)

IgD: 2 (<179)

IgM: 116 (26-218)

IgA: 111 (24-121)

IgG: 929 (533-1078)

IgG1: 594 (315-945)

IgG2: 136 (38-225)

IgG3: 52 (17-68)

**IgG4: 61.7 (1-54)

Vaccine titers (Fully vaccinated, with the exception of Varicella)

Measles IgG: 2.45 (> 1.10 = positive) -- are these very high?

Mumps IgG: 2.93 (> 1.10 = positive) -- are these very high?

Rubella IgG: 4.49 (> 1.10 = antibody detected) -- are these very high?

Hepatitis B surface antibody: Reactive

Varicella Zoster IgG: 2.64 (> 1.10 = positive)

HiB: 1.55 (> 1.0 = protective level)

Diphtheria Antitoxoid: 0.23 (> 0.01 = protective level)

Tetanus Antitoxoid: 1.00 (>0.15 = protective level)

Pertussis IgG: 3 (< 40)

Polio I, II, III Antibodies: <1:8 (antibody not detected)

Viral titers (< 0.90 = No antibody detected for all results below)

Cytomegalovirus IgG: < 0.90

Cytomegalovirus IgM: 0.59

Herpes Simplex - 1 IgG: 0.06

Herpes Simplex - 2 IgG: 0.06

HHV6 DNA, PCR: Not detected

Parvovirus B-19 IgG: 0.3

Epstein-Barr Virus-VCA IgG: 0.12

Epstein-Barr Virus-Nuclear IgG: 0.52

Strep/PANDAS (Ref range in brackets)

ASO: 7 (<150)

Anti-DNASE-B: < 60 (Preschool: <=60 titer)

----------------------------------------------------------\

--------------------------

Really sorry for the long email and the number of questions, but I am

unable to figure this out..

Any pointers would be super helpful.

Sarita

April 27, 2008

Thank you, Noel. We did have the IgG and subclasses tested. Below

are the results. Everything except for IgG4 is in range. Do these

results give you any better indication regarding for us?

Immunoglobulins (Ref range in brackets)

IgE: 58 (< 72)

IgD: 2 (<179)

IgM: 116 (26-218)

IgA: 111 (24-121)

IgG: 929 (533-1078)

IgG1: 594 (315-945)

IgG2: 136 (38-225)

IgG3: 52 (17-68)

**IgG4: 61.7 (1-54)

Sarita

>

> I am relatively new to the group and have been reading up the

archives

> since I joined to educate myself further. I apologize for the

length of

> this email, but I am feeling quite lost in our treatment path to

heal my

> son who has a diagnosis of autism. I would really appreciate any

> guidance from the group.

>

> My 3.8 yr old son has been largely a non-responder to the few

> bio-medical treatments tried to-date. I wanted to evaluate whether

it

> would make sense for us to next try anti-viral or IVIG or

treatment

> for him, and recently got back his blood IgG and viral titers test

> results from Quest Diagnostics.

>

> I feel like I am missing something to explain the contradiction in

test

> results vs his symptoms. My son had multiple ear infections, easily

> catches colds, has chronic swollen tonsils, and shows gamma strep

in his

> stool but his blood test results below seem to suggest that he

does not

> have PANDAS markers, most of his immunoglobulins except for IgG4

are in

> range, no major viral titer markers, and no crazily high vaccine

titers

> (in fact, he has no antibody to polio and pertussis even though he

was

> vaccinated).

>

> - Should anti-viral treatments be a priority for us?

> - What about relative priority for IVIG treatment? Does the

elevated

> IgG4 simply indicate food allergies or something else?

> - Are there instances where kids have stealth viruses that don't

show up

> in these test results?

>

> Below are the results

> ----------------------------------------------------------\

> -------------------------------

>

> Immunoglobulins (Ref range in brackets)

> IgE: 58 (< 72)

> IgD: 2 (<179)

> IgM: 116 (26-218)

> IgA: 111 (24-121)

>

> IgG: 929 (533-1078)

> IgG1: 594 (315-945)

> IgG2: 136 (38-225)

> IgG3: 52 (17-68)

> **IgG4: 61.7 (1-54)

>

> Vaccine titers (Fully vaccinated, with the exception of Varicella)

>

> Measles IgG: 2.45 (> 1.10 = positive) -- are these very high?

> Mumps IgG: 2.93 (> 1.10 = positive) -- are these very high?

> Rubella IgG: 4.49 (> 1.10 = antibody detected) -- are these very

high?

> Hepatitis B surface antibody: Reactive

> Varicella Zoster IgG: 2.64 (> 1.10 = positive)

> HiB: 1.55 (> 1.0 = protective level)

> Diphtheria Antitoxoid: 0.23 (> 0.01 = protective level)

> Tetanus Antitoxoid: 1.00 (>0.15 = protective level)

> Pertussis IgG: 3 (< 40)

> Polio I, II, III Antibodies: <1:8 (antibody not detected)

>

> Viral titers (< 0.90 = No antibody detected for all results below)

>

> Cytomegalovirus IgG: < 0.90

> Cytomegalovirus IgM: 0.59

> Herpes Simplex - 1 IgG: 0.06

> Herpes Simplex - 2 IgG: 0.06

> HHV6 DNA, PCR: Not detected

> Parvovirus B-19 IgG: 0.3

> Epstein-Barr Virus-VCA IgG: 0.12

> Epstein-Barr Virus-Nuclear IgG: 0.52

>

> Strep/PANDAS (Ref range in brackets)

> ASO: 7 (<150)

> Anti-DNASE-B: < 60 (Preschool: <=60 titer)

> ----------------------------------------------------------\

> --------------------------

> Really sorry for the long email and the number of questions, but I

am

> unable to figure this out..

>

> Any pointers would be super helpful.

>

> Sarita

>

April 27, 2008

Thank you, . We are waiting for our appointment with our

doctor to find out what he thinks. However, I have found many times

that the combined knowledge and experience of parents can often be

very insightful, and at times lead to things that the docs may miss.

So, I really appreciate your answer.

Our doctor didn't ask for the immune panel markers that you listed -

CD4, CD8, CD16, CD56. I wonder if I need to get these tested as

well, or whether the current results make that testing irrelevant or

not very useful in determining the choice of treatment.

Sarita

> >

> > I am relatively new to the group and have been reading up the

> archives

> > since I joined to educate myself further. I apologize for the

> length of

> > this email, but I am feeling quite lost in our treatment path to

> heal my

> > son who has a diagnosis of autism. I would really appreciate any

> > guidance from the group.

> >

> > My 3.8 yr old son has been largely a non-responder to the few

> > bio-medical treatments tried to-date. I wanted to evaluate

whether

> it

> > would make sense for us to next try anti-viral or IVIG or

> treatment

> > for him, and recently got back his blood IgG and viral titers

test

> > results from Quest Diagnostics.

> >

> > I feel like I am missing something to explain the contradiction

in

> test

> > results vs his symptoms. My son had multiple ear infections,

easily

> > catches colds, has chronic swollen tonsils, and shows gamma

strep

> in his

> > stool but his blood test results below seem to suggest that he

does

> not

> > have PANDAS markers, most of his immunoglobulins except for IgG4

> are in

> > range, no major viral titer markers, and no crazily high vaccine

> titers

> > (in fact, he has no antibody to polio and pertussis even though

he

> was

> > vaccinated).

> >

> > - Should anti-viral treatments be a priority for us?

> > - What about relative priority for IVIG treatment? Does the

elevated

> > IgG4 simply indicate food allergies or something else?

> > - Are there instances where kids have stealth viruses that don't

> show up

> > in these test results?

> >

> > Below are the results

> > -----------------------------------------------------------------

---

> ----\

> > -------------------------------

> >

> > Immunoglobulins (Ref range in brackets)

> > IgE: 58 (< 72)

> > IgD: 2 (<179)

> > IgM: 116 (26-218)

> > IgA: 111 (24-121)

> >

> > IgG: 929 (533-1078)

> > IgG1: 594 (315-945)

> > IgG2: 136 (38-225)

> > IgG3: 52 (17-68)

> > **IgG4: 61.7 (1-54)

> >

> > Vaccine titers (Fully vaccinated, with the exception of

Varicella)

> >

> > Measles IgG: 2.45 (> 1.10 = positive) -- are these very high?

> > Mumps IgG: 2.93 (> 1.10 = positive) -- are these very high?

> > Rubella IgG: 4.49 (> 1.10 = antibody detected) -- are these very

> high?

> > Hepatitis B surface antibody: Reactive

> > Varicella Zoster IgG: 2.64 (> 1.10 = positive)

> > HiB: 1.55 (> 1.0 = protective level)

> > Diphtheria Antitoxoid: 0.23 (> 0.01 = protective level)

> > Tetanus Antitoxoid: 1.00 (>0.15 = protective level)

> > Pertussis IgG: 3 (< 40)

> > Polio I, II, III Antibodies: <1:8 (antibody not detected)

> >

> > Viral titers (< 0.90 = No antibody detected for all results

below)

> >

> > Cytomegalovirus IgG: < 0.90

> > Cytomegalovirus IgM: 0.59

> > Herpes Simplex - 1 IgG: 0.06

> > Herpes Simplex - 2 IgG: 0.06

> > HHV6 DNA, PCR: Not detected

> > Parvovirus B-19 IgG: 0.3

> > Epstein-Barr Virus-VCA IgG: 0.12

> > Epstein-Barr Virus-Nuclear IgG: 0.52

> >

> > Strep/PANDAS (Ref range in brackets)

> > ASO: 7 (<150)

> > Anti-DNASE-B: < 60 (Preschool: <=60 titer)

> > -----------------------------------------------------------------

---

> ----\

> > --------------------------

> > Really sorry for the long email and the number of questions, but

I

> am

> > unable to figure this out..

> >

> > Any pointers would be super helpful.

> >

> > Sarita

> >

April 27, 2008

Hi Sarita,

What interventions have you tried?

Your son's symtoms sound very much like my son's. Diet has been a HUGE

intervention for him. We had to remove: casein, gluten, CORN, soy, food

dyes, preservatives, refined sugar (and limit other sugars).

He has also been on the protocol for over 2 years with very good

results.

Kristy

Go for anti-virals/IVIG/ or not?

I am relatively new to the group and have been reading up the archives

since I joined to educate myself further. I apologize for the length of

this email, but I am feeling quite lost in our treatment path to heal my

son who has a diagnosis of autism. I would really appreciate any

guidance from the group.

My 3.8 yr old son has been largely a non-responder to the few

bio-medical treatments tried to-date. I wanted to evaluate whether it

would make sense for us to next try anti-viral or IVIG or treatment

for him, and recently got back his blood IgG and viral titers test

results from Quest Diagnostics.

I feel like I am missing something to explain the contradiction in test

results vs his symptoms. My son had multiple ear infections, easily

catches colds, has chronic swollen tonsils, and shows gamma strep in his

stool but his blood test results below seem to suggest that he does not

have PANDAS markers, most of his immunoglobulins except for IgG4 are in

range, no major viral titer markers, and no crazily high vaccine titers

(in fact, he has no antibody to polio and pertussis even though he was

vaccinated).

- Should anti-viral treatments be a priority for us?

- What about relative priority for IVIG treatment? Does the elevated

IgG4 simply indicate food allergies or something else?

- Are there instances where kids have stealth viruses that don't show up

in these test results?

Below are the results

----------------------------------------------------------\

-------------------------------

Immunoglobulins (Ref range in brackets)

IgE: 58 (< 72)

IgD: 2 (<179)

IgM: 116 (26-218)

IgA: 111 (24-121)

IgG: 929 (533-1078)

IgG1: 594 (315-945)

IgG2: 136 (38-225)

IgG3: 52 (17-68)

**IgG4: 61.7 (1-54)

Vaccine titers (Fully vaccinated, with the exception of Varicella)

Measles IgG: 2.45 (> 1.10 = positive) -- are these very high?

Mumps IgG: 2.93 (> 1.10 = positive) -- are these very high?

Rubella IgG: 4.49 (> 1.10 = antibody detected) -- are these very high?

Hepatitis B surface antibody: Reactive

Varicella Zoster IgG: 2.64 (> 1.10 = positive)

HiB: 1.55 (> 1.0 = protective level)

Diphtheria Antitoxoid: 0.23 (> 0.01 = protective level)

Tetanus Antitoxoid: 1.00 (>0.15 = protective level)

Pertussis IgG: 3 (< 40)

Polio I, II, III Antibodies: <1:8 (antibody not detected)

Viral titers (< 0.90 = No antibody detected for all results below)

Cytomegalovirus IgG: < 0.90

Cytomegalovirus IgM: 0.59

Herpes Simplex - 1 IgG: 0.06

Herpes Simplex - 2 IgG: 0.06

HHV6 DNA, PCR: Not detected

Parvovirus B-19 IgG: 0.3

Epstein-Barr Virus-VCA IgG: 0.12

Epstein-Barr Virus-Nuclear IgG: 0.52

Strep/PANDAS (Ref range in brackets)

ASO: 7 (<150)

Anti-DNASE-B: < 60 (Preschool: <=60 titer)

----------------------------------------------------------\

--------------------------

Really sorry for the long email and the number of questions, but I am

unable to figure this out..

Any pointers would be super helpful.

Sarita

April 27, 2008

That would be " symptoms " .

Go for anti-virals/IVIG/ or not?

I am relatively new to the group and have been reading up the archives

since I joined to educate myself further. I apologize for the length of

this email, but I am feeling quite lost in our treatment path to heal my

son who has a diagnosis of autism. I would really appreciate any

guidance from the group.

My 3.8 yr old son has been largely a non-responder to the few

bio-medical treatments tried to-date. I wanted to evaluate whether it

would make sense for us to next try anti-viral or IVIG or treatment

for him, and recently got back his blood IgG and viral titers test

results from Quest Diagnostics.

I feel like I am missing something to explain the contradiction in test

results vs his symptoms. My son had multiple ear infections, easily

catches colds, has chronic swollen tonsils, and shows gamma strep in his

stool but his blood test results below seem to suggest that he does not

have PANDAS markers, most of his immunoglobulins except for IgG4 are in

range, no major viral titer markers, and no crazily high vaccine titers

(in fact, he has no antibody to polio and pertussis even though he was

vaccinated).

- Should anti-viral treatments be a priority for us?

- What about relative priority for IVIG treatment? Does the elevated

IgG4 simply indicate food allergies or something else?

- Are there instances where kids have stealth viruses that don't show up

in these test results?

Below are the results

----------------------------------------------------------\

-------------------------------

Immunoglobulins (Ref range in brackets)

IgE: 58 (< 72)

IgD: 2 (<179)

IgM: 116 (26-218)

IgA: 111 (24-121)

IgG: 929 (533-1078)

IgG1: 594 (315-945)

IgG2: 136 (38-225)

IgG3: 52 (17-68)

**IgG4: 61.7 (1-54)

Vaccine titers (Fully vaccinated, with the exception of Varicella)

Measles IgG: 2.45 (> 1.10 = positive) -- are these very high?

Mumps IgG: 2.93 (> 1.10 = positive) -- are these very high?

Rubella IgG: 4.49 (> 1.10 = antibody detected) -- are these very high?

Hepatitis B surface antibody: Reactive

Varicella Zoster IgG: 2.64 (> 1.10 = positive)

HiB: 1.55 (> 1.0 = protective level)

Diphtheria Antitoxoid: 0.23 (> 0.01 = protective level)

Tetanus Antitoxoid: 1.00 (>0.15 = protective level)

Pertussis IgG: 3 (< 40)

Polio I, II, III Antibodies: <1:8 (antibody not detected)

Viral titers (< 0.90 = No antibody detected for all results below)

Cytomegalovirus IgG: < 0.90

Cytomegalovirus IgM: 0.59

Herpes Simplex - 1 IgG: 0.06

Herpes Simplex - 2 IgG: 0.06

HHV6 DNA, PCR: Not detected

Parvovirus B-19 IgG: 0.3

Epstein-Barr Virus-VCA IgG: 0.12

Epstein-Barr Virus-Nuclear IgG: 0.52

Strep/PANDAS (Ref range in brackets)

ASO: 7 (<150)

Anti-DNASE-B: < 60 (Preschool: <=60 titer)

----------------------------------------------------------\

--------------------------

Really sorry for the long email and the number of questions, but I am

unable to figure this out..

Any pointers would be super helpful.

Sarita

April 28, 2008

Hi, I do think you would benefit from Nids, viruses don't always test positive

but once you begin treatment you see the titers come up and then go down....they

usually hide. We never had high titers either except for CMV. Most of the

world has elevated CMV but their immune systems keep it surpressed. It is like

people with cold sores, this is a herpes virus transmittable even though they

are asyptomatic. We did IVIG for 8mons, my son had low total IgG and was always

sick. I don't think IVIG is the right choice for you based on these labs, they

actually look pretty good. I stopped IVIG because my son began getting serum

sickness the side effects were terrible for us. After one infusion wihin 24-72

hrs we got vomitting/nausea/Headaches major..... I love the protocol. I did

DAN for 1 year with some improvements but nothing sustained. Hope this helps.

Noel

myasdprofile <asdmommy@...> wrote: Thank you, Noel. We did have

the IgG and subclasses tested. Below

are the results. Everything except for IgG4 is in range. Do these

results give you any better indication regarding for us?

Immunoglobulins (Ref range in brackets)

IgE: 58 (< 72)

IgD: 2 (<179)

IgM: 116 (26-218)

IgA: 111 (24-121)

IgG: 929 (533-1078)

IgG1: 594 (315-945)

IgG2: 136 (38-225)

IgG3: 52 (17-68)

**IgG4: 61.7 (1-54)

Sarita

>

> I am relatively new to the group and have been reading up the

archives

> since I joined to educate myself further. I apologize for the

length of

> this email, but I am feeling quite lost in our treatment path to

heal my

> son who has a diagnosis of autism. I would really appreciate any

> guidance from the group.

>

> My 3.8 yr old son has been largely a non-responder to the few

> bio-medical treatments tried to-date. I wanted to evaluate whether

it

> would make sense for us to next try anti-viral or IVIG or

treatment

> for him, and recently got back his blood IgG and viral titers test

> results from Quest Diagnostics.

>

> I feel like I am missing something to explain the contradiction in

test

> results vs his symptoms. My son had multiple ear infections, easily

> catches colds, has chronic swollen tonsils, and shows gamma strep

in his

> stool but his blood test results below seem to suggest that he

does not

> have PANDAS markers, most of his immunoglobulins except for IgG4

are in

> range, no major viral titer markers, and no crazily high vaccine

titers

> (in fact, he has no antibody to polio and pertussis even though he

was

> vaccinated).

>

> - Should anti-viral treatments be a priority for us?

> - What about relative priority for IVIG treatment? Does the

elevated

> IgG4 simply indicate food allergies or something else?

> - Are there instances where kids have stealth viruses that don't

show up

> in these test results?

>

> Below are the results

> ----------------------------------------------------------\

> -------------------------------

>

> Immunoglobulins (Ref range in brackets)

> IgE: 58 (< 72)

> IgD: 2 (<179)

> IgM: 116 (26-218)

> IgA: 111 (24-121)

>

> IgG: 929 (533-1078)

> IgG1: 594 (315-945)

> IgG2: 136 (38-225)

> IgG3: 52 (17-68)

> **IgG4: 61.7 (1-54)

>

> Vaccine titers (Fully vaccinated, with the exception of Varicella)

>

> Measles IgG: 2.45 (> 1.10 = positive) -- are these very high?

> Mumps IgG: 2.93 (> 1.10 = positive) -- are these very high?

> Rubella IgG: 4.49 (> 1.10 = antibody detected) -- are these very

high?

> Hepatitis B surface antibody: Reactive

> Varicella Zoster IgG: 2.64 (> 1.10 = positive)

> HiB: 1.55 (> 1.0 = protective level)

> Diphtheria Antitoxoid: 0.23 (> 0.01 = protective level)

> Tetanus Antitoxoid: 1.00 (>0.15 = protective level)

> Pertussis IgG: 3 (< 40)

> Polio I, II, III Antibodies: <1:8 (antibody not detected)

>

> Viral titers (< 0.90 = No antibody detected for all results below)

>

> Cytomegalovirus IgG: < 0.90

> Cytomegalovirus IgM: 0.59

> Herpes Simplex - 1 IgG: 0.06

> Herpes Simplex - 2 IgG: 0.06

> HHV6 DNA, PCR: Not detected

> Parvovirus B-19 IgG: 0.3

> Epstein-Barr Virus-VCA IgG: 0.12

> Epstein-Barr Virus-Nuclear IgG: 0.52

>

> Strep/PANDAS (Ref range in brackets)

> ASO: 7 (<150)

> Anti-DNASE-B: < 60 (Preschool: <=60 titer)

> ----------------------------------------------------------\

> --------------------------

> Really sorry for the long email and the number of questions, but I

am

> unable to figure this out..

>

> Any pointers would be super helpful.

>

> Sarita

>

April 28, 2008

Hi Noel,

My son also has a low IgG level, and had his first IVIG infusion on Friday. As

expected he had a fever, vomited and a terrible headache early Sunday morning

(3:00 AM). It was over as soon as it began, but still I was worried about

aseptic meningitis.

I totally agree with you about Sarita's son. His labs look really good:). Maybe

he needs to follow the straight protocol, and not look into IVIG as it

really isn't indicated. I wouldn't take the risk if I didn't need to.

Did you notice gains in your son's overall health since the IVIG treatments? My

son has been on antibiotics off and on for years, he has chronic sinus

infections and one virus after another. We've been on the protocol for five

years now but 's immune system still needed a boost. I'm hoping that he

won't need the IVIG for very long, I guess time will tell...

Take care,

@...: schneid99@...: Mon, 28 Apr 2008

07:38:18 -0700Subject: Re: Re: Go for anti-virals/IVIG/ or not?

Hi, I do think you would benefit from Nids, viruses don't always test positive

but once you begin treatment you see the titers come up and then go down....they

usually hide. We never had high titers either except for CMV. Most of the world

has elevated CMV but their immune systems keep it surpressed. It is like people

with cold sores, this is a herpes virus transmittable even though they are

asyptomatic. We did IVIG for 8mons, my son had low total IgG and was always

sick. I don't think IVIG is the right choice for you based on these labs, they

actually look pretty good. I stopped IVIG because my son began getting serum

sickness the side effects were terrible for us. After one infusion wihin 24-72

hrs we got vomitting/nausea/Headaches major..... I love the protocol. I did

DAN for 1 year with some improvements but nothing sustained. Hope this helps.

Noelmyasdprofile <asdmommy@...> wrote: Thank you, Noel. We did have the

IgG and subclasses tested. Below are the results. Everything except for IgG4 is

in range. Do these results give you any better indication regarding for

us?Immunoglobulins (Ref range in brackets)IgE: 58 (< 72)IgD: 2 (<179)IgM: 116

(26-218)IgA: 111 (24-121)IgG: 929 (533-1078)IgG1: 594 (315-945)IgG2: 136

(38-225)IgG3: 52 (17-68)**IgG4: 61.7 (1-54)Sarita > > I am relatively new to the

group and have been reading up the archives> since I joined to educate myself

further. I apologize for the length of> this email, but I am feeling quite lost

in our treatment path to heal my> son who has a diagnosis of autism. I would

really appreciate any> guidance from the group.> > My 3.8 yr old son has been

largely a non-responder to the few> bio-medical treatments tried to-date. I

wanted to evaluate whether it> would make sense for us to next try anti-viral or

IVIG or treatment> for him, and recently got back his blood IgG and viral

titers test> results from Quest Diagnostics.> > I feel like I am missing

something to explain the contradiction in test> results vs his symptoms. My son

had multiple ear infections, easily> catches colds, has chronic swollen tonsils,

and shows gamma strep in his> stool but his blood test results below seem to

suggest that he does not> have PANDAS markers, most of his immunoglobulins

except for IgG4 are in> range, no major viral titer markers, and no crazily high

vaccine titers> (in fact, he has no antibody to polio and pertussis even though

he was> vaccinated).> > - Should anti-viral treatments be a priority for us?> -

What about relative priority for IVIG treatment? Does the elevated> IgG4 simply

indicate food allergies or something else?> - Are there instances where kids

have stealth viruses that don't show up> in these test results?> > Below are the

results> ----------------------------------------------------------\>

-------------------------------> > Immunoglobulins (Ref range in brackets)> IgE:

58 (< 72)> IgD: 2 (<179)> IgM: 116 (26-218)> IgA: 111 (24-121)> > IgG: 929

(533-1078)> IgG1: 594 (315-945)> IgG2: 136 (38-225)> IgG3: 52 (17-68)> **IgG4:

61.7 (1-54)> > Vaccine titers (Fully vaccinated, with the exception of

Varicella)> > Measles IgG: 2.45 (> 1.10 = positive) -- are these very high?>

Mumps IgG: 2.93 (> 1.10 = positive) -- are these very high?> Rubella IgG: 4.49

(> 1.10 = antibody detected) -- are these very high?> Hepatitis B surface

antibody: Reactive> Varicella Zoster IgG: 2.64 (> 1.10 = positive)> HiB: 1.55 (>

1.0 = protective level)> Diphtheria Antitoxoid: 0.23 (> 0.01 = protective

level)> Tetanus Antitoxoid: 1.00 (>0.15 = protective level)> Pertussis IgG: 3 (<

40)> Polio I, II, III Antibodies: <1:8 (antibody not detected)> > Viral titers

(< 0.90 = No antibody detected for all results below)> > Cytomegalovirus IgG: <

0.90> Cytomegalovirus IgM: 0.59> Herpes Simplex - 1 IgG: 0.06> Herpes Simplex -

2 IgG: 0.06> HHV6 DNA, PCR: Not detected> Parvovirus B-19 IgG: 0.3> Epstein-Barr

Virus-VCA IgG: 0.12> Epstein-Barr Virus-Nuclear IgG: 0.52> > Strep/PANDAS (Ref

range in brackets)> ASO: 7 (<150)> Anti-DNASE-B: < 60 (Preschool: <=60 titer)>

----------------------------------------------------------\>

--------------------------> Really sorry for the long email and the number of

questions, but I am> unable to figure this out..> > Any pointers would be super

helpful.> > Sarita> >

April 28, 2008

Did Dr. G recommend IVIG? That's the first time I've heard of him

using it. What made him decide to go with it and not IMIG (or maybe

you did and it wasn't doing much?)?

Cheryl

On Apr 28, 2008, at 8:05 AM, LINDA A wrote:

>

> Hi Noel,

>

> My son also has a low IgG level, and had his first IVIG infusion on

> Friday. As expected he had a fever, vomited and a terrible headache

> early Sunday morning (3:00 AM). It was over as soon as it began,

> but still I was worried about aseptic meningitis.

>

> I totally agree with you about Sarita's son. His labs look really

> good:). Maybe he needs to follow the straight protocol, and

> not look into IVIG as it really isn't indicated. I wouldn't take

> the risk if I didn't need to.

>

> Did you notice gains in your son's overall health since the IVIG

> treatments? My son has been on antibiotics off and on for years, he

> has chronic sinus infections and one virus after another. We've

> been on the protocol for five years now but 's immune

> system still needed a boost. I'm hoping that he won't need the IVIG

> for very long, I guess time will tell...

>

> Take care,

>

> @...: schneid99@...: Mon, 28

> Apr 2008 07:38:18 -0700Subject: Re: Re: Go for anti-virals/

> IVIG/ or not?

>

> Hi, I do think you would benefit from Nids, viruses don't always

> test positive but once you begin treatment you see the titers come

> up and then go down....they usually hide. We never had high titers

> either except for CMV. Most of the world has elevated CMV but their

> immune systems keep it surpressed. It is like people with cold

> sores, this is a herpes virus transmittable even though they are

> asyptomatic. We did IVIG for 8mons, my son had low total IgG and

> was always sick. I don't think IVIG is the right choice for you

> based on these labs, they actually look pretty good. I stopped IVIG

> because my son began getting serum sickness the side effects were

> terrible for us. After one infusion wihin 24-72 hrs we got

> vomitting/nausea/Headaches major..... I love the protocol. I

> did DAN for 1 year with some improvements but nothing sustained.

> Hope this helps. Noelmyasdprofile <asdmommy@...> wrote: Thank

> you, Noel. We did have the IgG and subclasses tested. Below are the

> results. Everything except for IgG4 is in range. Do these results

> give you any better indication regarding for us?

> Immunoglobulins (Ref range in brackets)IgE: 58 (< 72)IgD: 2 (<179)

> IgM: 116 (26-218)IgA: 111 (24-121)IgG: 929 (533-1078)IgG1: 594

> (315-945)IgG2: 136 (38-225)IgG3: 52 (17-68)**IgG4: 61.7 (1-54)

> Sarita > > I am relatively new to the

> group and have been reading up the archives> since I joined to

> educate myself further. I apologize for the length of> this email,

> but I am feeling quite lost in our treatment path to heal my> son

> who has a diagnosis of autism. I would really appreciate any>

> guidance from the group.> > My 3.8 yr old son has been largely a

> non-responder to the few> bio-medical treatments tried to-date. I

> wanted to evaluate whether it> would make sense for us to next try

> anti-viral or IVIG or treatment> for him, and recently got

> back his blood IgG and viral titers test> results from Quest

> Diagnostics.> > I feel like I am missing something to explain the

> contradiction in test> results vs his symptoms. My son had multiple

> ear infections, easily> catches colds, has chronic swollen tonsils,

> and shows gamma strep in his> stool but his blood test results

> below seem to suggest that he does not> have PANDAS markers, most

> of his immunoglobulins except for IgG4 are in> range, no major

> viral titer markers, and no crazily high vaccine titers> (in fact,

> he has no antibody to polio and pertussis even though he was>

> vaccinated).> > - Should anti-viral treatments be a priority for us?

> > - What about relative priority for IVIG treatment? Does the

> elevated> IgG4 simply indicate food allergies or something else?> -

> Are there instances where kids have stealth viruses that don't show

> up> in these test results?> > Below are the results>

> ----------------------------------------------------------\>

> -------------------------------> > Immunoglobulins (Ref range in

> brackets)> IgE: 58 (< 72)> IgD: 2 (<179)> IgM: 116 (26-218)> IgA:

> 111 (24-121)> > IgG: 929 (533-1078)> IgG1: 594 (315-945)> IgG2: 136

> (38-225)> IgG3: 52 (17-68)> **IgG4: 61.7 (1-54)> > Vaccine titers

> (Fully vaccinated, with the exception of Varicella)> > Measles IgG:

> 2.45 (> 1.10 = positive) -- are these very high?> Mumps IgG: 2.93

> (> 1.10 = positive) -- are these very high?> Rubella IgG: 4.49 (>

> 1.10 = antibody detected) -- are these very high?> Hepatitis B

> surface antibody: Reactive> Varicella Zoster IgG: 2.64 (> 1.10 =

> positive)> HiB: 1.55 (> 1.0 = protective level)> Diphtheria

> Antitoxoid: 0.23 (> 0.01 = protective level)> Tetanus Antitoxoid:

> 1.00 (>0.15 = protective level)> Pertussis IgG: 3 (< 40)> Polio I,

> II, III Antibodies: <1:8 (antibody not detected)> > Viral titers (<

> 0.90 = No antibody detected for all results below)> >

> Cytomegalovirus IgG: < 0.90> Cytomegalovirus IgM: 0.59> Herpes

> Simplex - 1 IgG: 0.06> Herpes Simplex - 2 IgG: 0.06> HHV6 DNA, PCR:

> Not detected> Parvovirus B-19 IgG: 0.3> Epstein-Barr Virus-VCA IgG:

> 0.12> Epstein-Barr Virus-Nuclear IgG: 0.52> > Strep/PANDAS (Ref

> range in brackets)> ASO: 7 (<150)> Anti-DNASE-B: < 60 (Preschool:

> <=60 titer)>

> ----------------------------------------------------------\>

> --------------------------> Really sorry for the long email and the

> number of questions, but I am> unable to figure this out..> > Any

> pointers would be super helpful.> > Sarita> > [Non-text portions of

> this message have been removed]> > > > > > > Sincerely Noel> > >

>

April 28, 2008

I did IVIG with Dr. Gupta, I saw Dr. Ellis at CHOC also, but went with Dr. Gupta

because I liked the Gamunex he was using and Dr. Ellis used Gammagard, the

dosing was different. My son had the side effects for the first three infusions

and then the next three months he did awesome, the 7th and 8th infusion was

worse then the first three. I tested his immunoglobulins after being off for

two months of more and they were ok in good range, I will retest soon, hopefully

they are staying up. I can tell you he still gets sick like everyone else but it

is not nearly as bad. I know the IMIG is less risky and safer but not nearly as

effective. I do think the IVIG helped it played a big role thats why I am 100%

. Dr. Gupta is now using privigen. ( check spelling) he wanted to switch us

to that one but I want to hold off for now and see how things go. Hope this

helps. Noel

Cheryl Lowrance <c.lowrance@...> wrote: Did Dr. G recommend IVIG?

That's the first time I've heard of him