Go for anti-virals/IVIG/or not?

[Guest guest]

I am relatively new to the group and have been reading up the archives

since I joined to educate myself further. I apologize for the length of

this email, but I am feeling quite lost in our treatment path to heal my

son who has a diagnosis of autism. I would really appreciate any

guidance from the group.

My 3.8 yr old son has been largely a non-responder to the few

bio-medical treatments tried to-date. I wanted to evaluate whether it

would make sense for us to next try anti-viral or IVIG or treatment

for him, and recently got back his blood IgG and viral titers test

results from Quest Diagnostics.

I feel like I am missing something to explain the contradiction in test

results vs his symptoms. My son had multiple ear infections, easily

catches colds, has chronic swollen tonsils, and shows gamma strep in his

stool but his blood test results below seem to suggest that he does not

have PANDAS markers, most of his immunoglobulins except for IgG4 are in

range, no major viral titer markers, and no crazily high vaccine titers

(in fact, he has no antibody to polio and pertussis even though he was

vaccinated).

- Should anti-viral treatments be a priority for us?

- What about relative priority for IVIG treatment? Does the elevated

IgG4 simply indicate food allergies or something else?

- Are there instances where kids have stealth viruses that don't show up

in these test results?

Below are the results

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Immunoglobulins (Ref range in brackets)

IgE: 58 (< 72)

IgD: 2 (<179)

IgM: 116 (26-218)

IgA: 111 (24-121)

IgG: 929 (533-1078)

IgG1: 594 (315-945)

IgG2: 136 (38-225)

IgG3: 52 (17-68)

**IgG4: 61.7 (1-54)

Vaccine titers (Fully vaccinated, with the exception of Varicella)

Measles IgG: 2.45 (> 1.10 = positive) -- are these very high?

Mumps IgG: 2.93 (> 1.10 = positive) -- are these very high?

Rubella IgG: 4.49 (> 1.10 = antibody detected) -- are these very high?

Hepatitis B surface antibody: Reactive

Varicella Zoster IgG: 2.64 (> 1.10 = positive)

HiB: 1.55 (> 1.0 = protective level)

Diphtheria Antitoxoid: 0.23 (> 0.01 = protective level)

Tetanus Antitoxoid: 1.00 (>0.15 = protective level)

Pertussis IgG: 3 (< 40)

Polio I, II, III Antibodies: <1:8 (antibody not detected)

Viral titers (< 0.90 = No antibody detected for all results below)

Cytomegalovirus IgG: < 0.90

Cytomegalovirus IgM: 0.59

Herpes Simplex - 1 IgG: 0.06

Herpes Simplex - 2 IgG: 0.06

HHV6 DNA, PCR: Not detected

Parvovirus B-19 IgG: 0.3

Epstein-Barr Virus-VCA IgG: 0.12

Epstein-Barr Virus-Nuclear IgG: 0.52

Strep/PANDAS (Ref range in brackets)

ASO: 7 (<150)

Anti-DNASE-B: < 60 (Preschool: <=60 titer)

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Really sorry for the long email and the number of questions, but I am

unable to figure this out..

Any pointers would be super helpful.

Sarita