Re: Another Latest BullSh__ Article... Where do they get this from???

[Guest guest]

Did you see the Merck article I posted a few hours ago? They

describe exactly what we believe in... . I wonder if this is

one of the pharmaceutical companies he is working with...

I agree with you, it just doesn't make sense of why so many people

are trying to find something that doesn't exist.

What don't they look at the children that are recovering for a real

solution to the problem?

Thanks

>

>

> Gene sweep yields half a dozen autism culprits

> Variety of mutations keep brain from forming proper connections

>

>

> _

>

> Video

> _ (javascript:vPlayer('25626825','bf3917d4-2777-45de-b828-

9fd8a3e38390'))

>

>

> (javascript:vPlayer('25626825','bf3917d4-2777-45de-b828-

9fd8a3e38390'))

> _Study uncovers new genetic link to autism_

> (javascript:vPlayer('25626825','bf3917d4-2777-45de-b828-

9fd8a3e38390'))

> July 10: Harvard researchers have uncovered at least six new

genes that can

> increase the risk for autism, providing hope that doctors can

identify

> at-risk children earlier. NBC’s Bazell reports.

> Nightly News

>

> _

>

>

> Most popular

> • Most viewed • Top rated • Most e-mailed

>

> _ (http://www.msnbc.msn.com/id/25673296) _Magazine's 'satirical'

cover stirs

> controversy_ (http://www.msnbc.msn.com/id/25673296/)

> _Shirtless calendar’s creator excommunicated_

> (http://www.msnbc.msn.com/id/25667782/)

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(http://www.msnbc.msn.com/id/23694559/)

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> (http://www.msnbc.msn.com/id/25673485/)

> (http://www.msnbc.msn.com/id/25674571) _Bush calls on Congress

to lift

> oil drilling ban_ (http://www.msnbc.msn.com/id/25674571/)

> _Most viewed on msnbc.com_ (http://www.msnbc.msn.com/id/7468311/)

>

>

> _Pioneering heart surgeon DeBakey dead at 99_

> (http://www.msnbc.msn.com/id/25649134/)

> _Sick orphan baby finds a family in the hospital_

> (http://www.msnbc.msn.com/id/25589588/)

> _Shortage of teachers means shortage of nurses_

> (http://www.msnbc.msn.com/id/25626353/)

> _Sudanese president is charged with genocide_

> (http://www.msnbc.msn.com/id/25671505/)

> _World's oldest blogger signs off at age 108_

> (http://www.msnbc.msn.com/id/25668181/)

> _Most viewed on msnbc.com_ (http://www.msnbc.msn.com/id/7468311/)

>

>

> (http://www.msnbc.msn.com/id/25673296) _Magazine's 'satirical'

cover stirs

> controversy_ (http://www.msnbc.msn.com/id/25673296/)

> _Shirtless calendar’s creator excommunicated_

> (http://www.msnbc.msn.com/id/25667782/)

> _New Yorker Obama cover a satire or mistake?_

> (http://www.msnbc.msn.com/id/25673485/)

> _InBev acquiring Anheuser-Busch for $52 billion_

> (http://www.msnbc.msn.com/id/25663923/)

> _FAA announces runway safety improvements_

> (http://www.msnbc.msn.com/id/25675511/)

> _Most viewed on msnbc.com_ (http://www.msnbc.msn.com/id/7468311/)

>

>

>

>

>

>

>

>

>

> updated 7:23 p.m. ET, Thurs., July. 10, 2008

>

> WASHINGTON - Harvard researchers have discovered half a dozen new

genes

> involved in autism that suggest the disorder strikes in a brain

that can't

> properly form new connections.

> The findings also may help explain why intense education programs

do help

> some autistic children †" because certain genes that respond to

experience

> weren't missing, they were just stuck in the " off " position.

> " The circuits are there but you have to give it an extra push, "

said Dr.

> Goldstein of the Kennedy Krieger Institute in Baltimore,

which wasn't

> involved in the gene hunt but is well-known for its autism

behavioral therapy.

> The genetics suggest that " what we're doing makes sense when we

work with

> these little kids †" and work and work and work †" and suddenly

get through, " he

> said.

> But the study's bigger message is that autism is too strikingly

individual

> to envision an easy gene test for it. Instead, patients are

turning out to

> have a wide variety, almost a custom set, of gene defects.

> " Almost every kid with autism has their own particular cause of

it, " said

> Dr. Walsh, chief of genetics at Children's Hospital

Boston, who led

> the research published in Friday's edition of the journal

Science.

> Autism spectrum disorders include a range of poorly understood

brain

> conditions, from the mild Asperger's syndrome to more severe

autism characterized by

> poor social interaction, impaired communication and repetitious

behaviors.

> It's clear that genes play a big role in autism, from studies of

twins and

> families with multiple affected children. But so far, the genetic

cause is

> known for only about 15 percent of autism cases, Walsh said.

> Large chunks of missing DNA

> So Walsh's team took a new tack. They turned to the Middle East,

a part of

> the world with large families and a tendency for cousins to

marry,

> characteristics that increase the odds of finding rare genes.

They recruited 88 families

> with cousin marriages and a high incidence of autism, from

Jordan, Saudi

> Arabia, Kuwait, Oman, Pakistan, Qatar, Turkey and the United Arab

Emirates. They

> compared the DNA of family members to search for what are called

recessive

> mutations †" where mom and dad can be healthy carriers of a gene

defect but a

> child who inherits that defect from both parents gets sick.

>

> Click for related content

> _Fringe autism treatment could get federal study_

> (http://www.msnbc.msn.com/id/25591927/)

> _Autistic students get help navigating college life_

> (http://www.msnbc.msn.com/id/25588421/)

>

> In some of the families, they found large chunks of missing DNA

regions that

> followed that recessive rule. The missing regions varied among

families, but

> they affected at least six genes that play a role in autism.

> Here's why this matters: All the genes seem to be part of a

network involved

> in a basic foundation of learning †" how neurons respond to new

experiences

> by forming connections between each other, called synapses.

> In the first year or two of life †" when autism symptoms appear

†" synapses

> rapidly form and mature, and unnecessary ones are " pruned " back.

In other

> words, a baby's brain is literally being shaped by its first

experiences so that

> it is structurally able to perform learning and other functions

of later

> life.

> Troubles sculpting the brain

> " This paper points to problems specifically in the way that

experience

> sculpts the developing brain, " explained Dr. Insel,

director of the

> National Institute of Mental Health, which helped fund the work.

> Some earlier research had pointed to the same underlying problem,

so these

> newly found genes " join a growing list to suggest that autism is

a synaptic

> disorder, " he said.

> If that sounds discouraging, here's the good news: The missing

DNA didn't

> always translate into missing genes. Instead what usually was

missing were the

> on/off switches for these autism-related genes. Essentially, some

genes were

> asleep instead of doing their synapse work.

> " I find that hopeful " because " there are ways that are being

discovered to

> activate genes, " Walsh said. " This might be an unanticipated way

of developing

> therapies in the long term for autism: Identifying these kids

where all the

> right genes are present, just not turned on in the right way. "

> At Kennedy Krieger, Goldstein thinks the work may provide a gene-

level

> explanation for why some children already are helped by intense

therapy.

> " We have trouble getting through to these children, but with

repeated

> stimulation we can do it, " he said. " These are circuits that have

an ability not so

> much to recover but to work around the problem.

>

>

> " Ms. Michele "

>

>

>

>

>

>

> **************Get the scoop on last night's hottest shows and the

live music

> scene in your area - Check out TourTracker.com!

> (http://www.tourtracker.com?NCID=aolmus00050000000112)

>

>

>

[Guest guest]

They are saying this applies to only 15% of autism cases.

Why is it bullsh__, in your opinion????

Kristy

From: [mailto: ] On Behalf Of

isoaa@...

Sent: Monday, July 14, 2008 11:51 AM

Subject: Another Latest BullSh__ Article... Where do they get this

from???

Gene sweep yields half a dozen autism culprits

Variety of mutations keep brain from forming proper connections

_

Video

_ (javascript:vPlayer('25626825','bf3917d4-2777-45de-b828-9fd8a3e38390'))

(javascript:vPlayer('25626825','bf3917d4-2777-45de-b828-9fd8a3e38390'))

_Study uncovers new genetic link to autism_

(javascript:vPlayer('25626825','bf3917d4-2777-45de-b828-9fd8a3e38390'))

July 10: Harvard researchers have uncovered at least six new genes that can

increase the risk for autism, providing hope that doctors can identify

at-risk children earlier. NBC’s Bazell reports.

Nightly News

_

Most popular

• Most viewed • Top rated • Most e-mailed

_ (http://www.msnbc.msn.com/id/25673296) _Magazine's 'satirical' cover stirs

controversy_ (http://www.msnbc.msn.com/id/25673296/)

_Shirtless calendar’s creator excommunicated_

(http://www.msnbc.msn.com/id/25667782/)

_Check out these ambush makeovers!_ (http://www.msnbc.msn.com/id/23694559/)

_New Yorker Obama cover a satire or mistake?_

(http://www.msnbc.msn.com/id/25673485/)

(http://www.msnbc.msn.com/id/25674571) _Bush calls on Congress to lift

oil drilling ban_ (http://www.msnbc.msn.com/id/25674571/)

_Most viewed on msnbc.com_ (http://www.msnbc.msn.com/id/7468311/)

_Pioneering heart surgeon DeBakey dead at 99_

(http://www.msnbc.msn.com/id/25649134/)

_Sick orphan baby finds a family in the hospital_

(http://www.msnbc.msn.com/id/25589588/)

_Shortage of teachers means shortage of nurses_

(http://www.msnbc.msn.com/id/25626353/)

_Sudanese president is charged with genocide_

(http://www.msnbc.msn.com/id/25671505/)

_World's oldest blogger signs off at age 108_

(http://www.msnbc.msn.com/id/25668181/)

_Most viewed on msnbc.com_ (http://www.msnbc.msn.com/id/7468311/)

(http://www.msnbc.msn.com/id/25673296) _Magazine's 'satirical' cover stirs

controversy_ (http://www.msnbc.msn.com/id/25673296/)

_Shirtless calendar’s creator excommunicated_

(http://www.msnbc.msn.com/id/25667782/)

_New Yorker Obama cover a satire or mistake?_

(http://www.msnbc.msn.com/id/25673485/)

_InBev acquiring Anheuser-Busch for $52 billion_

(http://www.msnbc.msn.com/id/25663923/)

_FAA announces runway safety improvements_

(http://www.msnbc.msn.com/id/25675511/)

_Most viewed on msnbc.com_ (http://www.msnbc.msn.com/id/7468311/)

updated 7:23 p.m. ET, Thurs., July. 10, 2008

WASHINGTON - Harvard researchers have discovered half a dozen new genes

involved in autism that suggest the disorder strikes in a brain that can't

properly form new connections.

The findings also may help explain why intense education programs do help

some autistic children — because certain genes that respond to experience

weren't missing, they were just stuck in the " off " position.

" The circuits are there but you have to give it an extra push, " said Dr.

Goldstein of the Kennedy Krieger Institute in Baltimore, which wasn't

involved in the gene hunt but is well-known for its autism behavioral therapy.

The genetics suggest that " what we're doing makes sense when we work with

these little kids — and work and work and work — and suddenly get through, "

he

said.

But the study's bigger message is that autism is too strikingly individual

to envision an easy gene test for it. Instead, patients are turning out to

have a wide variety, almost a custom set, of gene defects.

" Almost every kid with autism has their own particular cause of it, " said

Dr. Walsh, chief of genetics at Children's Hospital Boston, who led

the research published in Friday's edition of the journal Science.

Autism spectrum disorders include a range of poorly understood brain

conditions, from the mild Asperger's syndrome to more severe autism

characterized by

poor social interaction, impaired communication and repetitious behaviors.

It's clear that genes play a big role in autism, from studies of twins and

families with multiple affected children. But so far, the genetic cause is

known for only about 15 percent of autism cases, Walsh said.

Large chunks of missing DNA

So Walsh's team took a new tack. They turned to the Middle East, a part of

the world with large families and a tendency for cousins to marry,

characteristics that increase the odds of finding rare genes. They recruited 88

families

with cousin marriages and a high incidence of autism, from Jordan, Saudi

Arabia, Kuwait, Oman, Pakistan, Qatar, Turkey and the United Arab Emirates. They

compared the DNA of family members to search for what are called recessive

mutations — where mom and dad can be healthy carriers of a gene defect but a

child who inherits that defect from both parents gets sick.

Click for related content

_Fringe autism treatment could get federal study_

(http://www.msnbc.msn.com/id/25591927/)

_Autistic students get help navigating college life_

(http://www.msnbc.msn.com/id/25588421/)

In some of the families, they found large chunks of missing DNA regions that

followed that recessive rule. The missing regions varied among families, but

they affected at least six genes that play a role in autism.

Here's why this matters: All the genes seem to be part of a network involved

in a basic foundation of learning — how neurons respond to new experiences

by forming connections between each other, called synapses.

In the first year or two of life — when autism symptoms appear — synapses

rapidly form and mature, and unnecessary ones are " pruned " back. In other

words, a baby's brain is literally being shaped by its first experiences so that

it is structurally able to perform learning and other functions of later

life.

Troubles sculpting the brain

" This paper points to problems specifically in the way that experience

sculpts the developing brain, " explained Dr. Insel, director of the

National Institute of Mental Health, which helped fund the work.

Some earlier research had pointed to the same underlying problem, so these

newly found genes " join a growing list to suggest that autism is a synaptic

disorder, " he said.

If that sounds discouraging, here's the good news: The missing DNA didn't

always translate into missing genes. Instead what usually was missing were the

on/off switches for these autism-related genes. Essentially, some genes were

asleep instead of doing their synapse work.

" I find that hopeful " because " there are ways that are being discovered to

activate genes, " Walsh said. " This might be an unanticipated way of developing

therapies in the long term for autism: Identifying these kids where all the

right genes are present, just not turned on in the right way. "

At Kennedy Krieger, Goldstein thinks the work may provide a gene-level

explanation for why some children already are helped by intense therapy.

" We have trouble getting through to these children, but with repeated

stimulation we can do it, " he said. " These are circuits that have an ability not

so

much to recover but to work around the problem.

" Ms. Michele "

**************Get the scoop on last night's hottest shows and the live music

scene in your area - Check out TourTracker.com!

(http://www.tourtracker.com?NCID=aolmus00050000000112)

[Guest guest]

I think that the more they learn about epigenetics, they will discover more and

more ways that the immune system and viruses can switch these genes on and off. 

Another Latest BullSh__ Article... Where do they get this

from???

Gene sweep yields half a dozen autism culprits

Variety of mutations keep brain from forming proper connections

_

Video

_ (javascript: vPlayer(' 25626825' ,'bf3917d4- 2777-45de- b828-9fd8a3e3839 0'))

(javascript: vPlayer(' 25626825' ,'bf3917d4- 2777-45de- b828-9fd8a3e3839 0'))

_Study uncovers new genetic link to autism_

(javascript: vPlayer(' 25626825' ,'bf3917d4- 2777-45de- b828-9fd8a3e3839 0'))

July 10: Harvard researchers have uncovered at least six new genes that can

increase the risk for autism, providing hope that doctors can identify

at-risk children earlier. NBC’s Bazell reports.

Nightly News

_

Most popular

• Most viewed • Top rated • Most e-mailed

_ (http://www.msnbc. msn.com/id/ 25673296) _Magazine's 'satirical' cover stirs

controversy_ (http://www.msnbc. msn.com/id/ 25673296/)

_Shirtless calendar’s creator excommunicated_

(http://www.msnbc. msn.com/id/ 25667782/)

_Check out these ambush makeovers!_ (http://www.msnbc. msn.com/id/ 23694559/)

_New Yorker Obama cover a satire or mistake?_

(http://www.msnbc. msn.com/id/ 25673485/)

(http://www.msnbc. msn.com/id/ 25674571) _Bush calls on Congress to lift

oil drilling ban_ (http://www.msnbc. msn.com/id/ 25674571/)

_Most viewed on msnbc.com_ (http://www.msnbc. msn.com/id/ 7468311/)

_Pioneering heart surgeon DeBakey dead at 99_

(http://www.msnbc. msn.com/id/ 25649134/)

_Sick orphan baby finds a family in the hospital_

(http://www.msnbc. msn.com/id/ 25589588/)

_Shortage of teachers means shortage of nurses_

(http://www.msnbc. msn.com/id/ 25626353/)

_Sudanese president is charged with genocide_

(http://www.msnbc. msn.com/id/ 25671505/)

_World's oldest blogger signs off at age 108_

(http://www.msnbc. msn.com/id/ 25668181/)

_Most viewed on msnbc.com_ (http://www.msnbc. msn.com/id/ 7468311/)

(http://www.msnbc. msn.com/id/ 25673296) _Magazine's 'satirical' cover stirs

controversy_ (http://www.msnbc. msn.com/id/ 25673296/)

_Shirtless calendar’s creator excommunicated_

(http://www.msnbc. msn.com/id/ 25667782/)

_New Yorker Obama cover a satire or mistake?_

(http://www.msnbc. msn.com/id/ 25673485/)

_InBev acquiring Anheuser-Busch for $52 billion_

(http://www.msnbc. msn.com/id/ 25663923/)

_FAA announces runway safety improvements_

(http://www.msnbc. msn.com/id/ 25675511/)

_Most viewed on msnbc.com_ (http://www.msnbc. msn.com/id/ 7468311/)

updated 7:23 p.m. ET, Thurs., July. 10, 2008

WASHINGTON - Harvard researchers have discovered half a dozen new genes

involved in autism that suggest the disorder strikes in a brain that can't

properly form new connections.

The findings also may help explain why intense education programs do help

some autistic children — because certain genes that respond to experience

weren't missing, they were just stuck in the " off " position.

" The circuits are there but you have to give it an extra push, " said Dr.

Goldstein of the Kennedy Krieger Institute in Baltimore, which wasn't

involved in the gene hunt but is well-known for its autism behavioral therapy.

The genetics suggest that " what we're doing makes sense when we work with

these little kids — and work and work and work — and suddenly get through, " he

said.

But the study's bigger message is that autism is too strikingly individual

to envision an easy gene test for it. Instead, patients are turning out to

have a wide variety, almost a custom set, of gene defects.

" Almost every kid with autism has their own particular cause of it, " said

Dr. Walsh, chief of genetics at Children's Hospital Boston, who led

the research published in Friday's edition of the journal Science.

Autism spectrum disorders include a range of poorly understood brain

conditions, from the mild Asperger's syndrome to more severe autism

characterized by

poor social interaction, impaired communication and repetitious behaviors.

It's clear that genes play a big role in autism, from studies of twins and

families with multiple affected children. But so far, the genetic cause is

known for only about 15 percent of autism cases, Walsh said.

Large chunks of missing DNA

So Walsh's team took a new tack. They turned to the Middle East, a part of

the world with large families and a tendency for cousins to marry,

characteristics that increase the odds of finding rare genes. They recruited 88

families

with cousin marriages and a high incidence of autism, from Jordan, Saudi

Arabia, Kuwait, Oman, Pakistan, Qatar, Turkey and the United Arab Emirates. They

compared the DNA of family members to search for what are called recessive

mutations — where mom and dad can be healthy carriers of a gene defect but a

child who inherits that defect from both parents gets sick.

Click for related content

_Fringe autism treatment could get federal study_

(http://www.msnbc. msn.com/id/ 25591927/)

_Autistic students get help navigating college life_

(http://www.msnbc. msn.com/id/ 25588421/)

In some of the families, they found large chunks of missing DNA regions that

followed that recessive rule. The missing regions varied among families, but

they affected at least six genes that play a role in autism.

Here's why this matters: All the genes seem to be part of a network involved

in a basic foundation of learning — how neurons respond to new experiences

by forming connections between each other, called synapses.

In the first year or two of life — when autism symptoms appear — synapses

rapidly form and mature, and unnecessary ones are " pruned " back. In other

words, a baby's brain is literally being shaped by its first experiences so that

it is structurally able to perform learning and other functions of later

life.

Troubles sculpting the brain

" This paper points to problems specifically in the way that experience

sculpts the developing brain, " explained Dr. Insel, director of the

National Institute of Mental Health, which helped fund the work.

Some earlier research had pointed to the same underlying problem, so these

newly found genes " join a growing list to suggest that autism is a synaptic

disorder, " he said.

If that sounds discouraging, here's the good news: The missing DNA didn't

always translate into missing genes. Instead what usually was missing were the

on/off switches for these autism-related genes. Essentially, some genes were

asleep instead of doing their synapse work.

" I find that hopeful " because " there are ways that are being discovered to

activate genes, " Walsh said. " This might be an unanticipated way of developing

therapies in the long term for autism: Identifying these kids where all the

right genes are present, just not turned on in the right way. "

At Kennedy Krieger, Goldstein thinks the work may provide a gene-level

explanation for why some children already are helped by intense therapy.

" We have trouble getting through to these children, but with repeated

stimulation we can do it, " he said. " These are circuits that have an ability not

so

much to recover but to work around the problem.

" Ms. Michele "

************ **Get the scoop on last night's hottest shows and the live music

scene in your area - Check out TourTracker. com!

(http://www.tourtrac ker.com?NCID= aolmus0005000000 0112)