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Has anybody tried Ibuprofen to reduce brain inflammation?

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Hi,

My son had the flu and a bacterial infection one after the other

back in February. We gave him Children's Motrin for 8 days in a row

to keep the fever down. We noticed that during the time he was

sick, he looked more alert, talking more, less echoleia and less

spacey. We were shocked by it. He didn't take ABA during the time

he was sick, approximately 2 weeks. When he resumed his ABA

treatment, his therapists were amazed on how much sharper his was.

My son had a SPECT scan two weeks prior getting sick at Dr. Uszler's

office in California. The SPECT scan showed hypoperfusion in his

temporal lobes. Dr. Uszler told us that it could be inflammation

due to a viral infection and referred us to Dr. Goldberg.

In the meantime I talked to my son's DAN doctor which happens to be

an immunologist and told him our story. He told me many of his

patients got better after being sick with viral or bacterial

infections. So he told me it made sense that it could be because

some parents use Motrin to reduce fever.

We had our first appointment with Dr. Goldberg a few weeks

ago and I mentioned my son's improvements after the Ibuprofen and he

said it could be possible. He also said that it could be

benefitial, but it could have damaging side effects and that is why

he will not prescribe it to his patients.

Ibuprofen works as an anti-inflammatory drug by inhibiting the

generation of cytokines which is the substance that creates

inflammation. Also, Ibuprofen can rapidly cross the blood brain

barrier so it can work on the brain effectively. There is a lot of

information in the internet about how Ibuprofen is now being used to

prevent and treat Alzheimer's which is also caused by brain

inflammation.

I am wondering if anybody have ever tried to give a Ibuprofen to

their children and have they noticed a difference? We are thinking

to do a 1-2 week Ibuprofen therapy to see if there are huge gains as

when we gave it to him the first time.

Thanks,

Dr. Goldberg's testimony on Capitol Hill

http://www.nids.net/testimony.htm

This may be a holding approach thus far wherein balancing the many

neurological immune regulating proteins known as cytokines and

chemokines may in turn rebalance behavior itself.

Ibuprofen brain uptake study

http://www.springerlink.com/content/r2113r556m136244/

Ibuprofen & Alzheimer's

http://www.webmd.com/news/20000810/alzheimers-take-two-ibuprofen-

call-me-in-morning

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