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HIV and autism

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I posted things in the past on similarities to autism in HIV positive kids.

Now have been looking more closely and cannot believe my eyes. Somebody

pinch me please.

So here¹s my rough summary as of today (it gets more interesting as you read

on, promise :)

Neurodevelopmenal findings in HIV kids:

Impairments in language, especially expressive language. Behavioural

symptoms: irritability, lack of social skills, repetitive actions (rocking

etc etc all familiar sounding). Note: memory and visual information

processing (visual intelligence) are NOT impaired.

Sometimes children develop normally and regress later, usually between 1.5-2

years of age. This is often linked to increased HIV viral load and/or

reactivation.

Now see this: language and behaviour often recover when children are given

combination antiretroviral treatments, at least to some degree. Sometimes

recovery is complete.

No mention of the A word. This is called peadiatric neuroaids or 5 other

vague names.

++++++

Latent HIV virus can be reactivated by vaccinations.

Live virus vaccines, especially MMR, often come with a warning for HIV

infected individuals ­ inability to mount apropriate immune responses

results in vaccine virus persistance. For example polio vacine strain has

been found alive and well in guts of vaccinated individuals. No antibody

production to Dtp or measles viruse etcŠ

++++++

Gastrointestinal findings in HIV positive children:

Leaky gut and malabsorbtion of nutrients

Lack of digestive enzymes (impaired pancreatic function)

Abnormal reactions to gluten and casein !!

Lactose intolerance

Sugar intolerance

Inability to digest complex carbohydrates

Inability to absorb fats and proteins

Gastrointestinal pathogen overload: secondary intestinal viruses, bacterial

overload.

Abnormal immune reactivity to candida albicans.

+++++

Impaired fine and gross motor skills in HIV positive children

Impaired sensory ­ auditory and visual processing

Subclinical hypothyroidism (in adults, no data on children)

++++++

HIV causes calcium overload and mitochondrial dysfunction

HIV causes oxidative stress and glutathione depletion

HIV is inhibited by glutathione and agents that raise glutathione

HIV causes microglial activation and inflammation

HIV alone or combined with bacterial agents causes breakdown of the blood

brain barrier

+++++

And this: chelation of metals inhibits HIV virus integration into human DNA.

Retroviruses (HIV is a retrovirus) in general are desintegrated by chelation

agents.

Retroviruses use metal complexes to integrate into human DNA

+++++

Tetracycline antibiotics (minocycline is one) inhibit HIV through same

mechanism as chelation agents

+++++

.....

Can I say anything out loud?

Gonna go to sleep now

------ End of Forwarded Message

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