Guest guest Posted April 28, 2009 Report Share Posted April 28, 2009 Tonight CBS Evening News has advertised that there will be a story about... ³New information about the role genetics plays in autism. We'll tell you about a breakthrough study, that sheds new light on the mystery of who gets the disorder and why.² It may just be old ³recycled² news, but just in case anyone wanted to watch it, I thought I¹d post it. I¹m sure they¹ll have info on the story on their website tomorrow. Caroline Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 29, 2009 Report Share Posted April 29, 2009 I looked up the ³autism breakthrough² story that CBS Evening News showed last night and here are some links... http://www.cbsnews.com/stories/2009/04/28/eveningnews/main4975659.shtml http://www.webmd.com/brain/autism/news/20090428/gene-variants-hold-new-clues -to-autism .... the study¹s lead author was Hakon Hakonarson of Children's Hospital of Philadelphia. Interesting read. Caroline Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 29, 2009 Report Share Posted April 29, 2009 There is a piece in today’s LA Times about this..see http://www.latimes.com/news/nationworld/nation/la-na-autism29-2009apr29,0,75 35659.story _____ From: [mailto: ] On Behalf Of Caroline Glover Sent: Tuesday, April 28, 2009 9:44 AM Subject: Re: CBS Evening News Tonight CBS Evening News has advertised that there will be a story about... ³New information about the role genetics plays in autism. We'll tell you about a breakthrough study, that sheds new light on the mystery of who gets the disorder and why.² It may just be old ³recycled² news, but just in case anyone wanted to watch it, I thought I¹d post it. I¹m sure they¹ll have info on the story on their website tomorrow. Caroline Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 29, 2009 Report Share Posted April 29, 2009 One more link on this topic... and it contains links to the broadcasts available online... http://www.autismspeaks.org/press/autism_genes_discovered_chop.php Caroline Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 29, 2009 Report Share Posted April 29, 2009 I am confused, The CBS story stated that the mutation is in nearly 65 percent of the autistic population but the Autism Speaks website said that is in 15 percent of the population. Here is the link to the Autism Speaks website: http://www.autismspeaks.org/press/autism_genes_discovered_chop.php. Either way, it is exciting but I have never seen a percentage as high as 65 percent. If that is accurate, this is really huge. Thank you for the links. All the best, Jill From: Caroline Glover <sfglover@...> Subject: Re: CBS Evening News Date: Wednesday, April 29, 2009, 1:03 PM I looked up the ³autism breakthrough² story that CBS Evening News showed last night and here are some links... http://www.cbsnews. com/stories/ 2009/04/28/ eveningnews/ main4975659. shtml http://www.webmd. com/brain/ autism/news/ 20090428/ gene-variants- hold-new- clues -to-autism .... the study¹s lead author was Hakon Hakonarson of Children's Hospital of Philadelphia. Interesting read. Caroline Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 29, 2009 Report Share Posted April 29, 2009 I am confused, The CBS story stated that the mutation is in nearly 65 percent of the autistic population but the Autism Speaks website said that is in 15 percent of the population. Here is the link to the Autism Speaks website: http://www.autismspeaks.org/press/autism_genes_discovered_chop.php. Either way, it is exciting but I have never seen a percentage as high as 65 percent. If that is accurate, this is really huge. Thank you for the links. All the best, Jill From: Caroline Glover <sfglover@...> Subject: Re: CBS Evening News Date: Wednesday, April 29, 2009, 1:03 PM I looked up the ³autism breakthrough² story that CBS Evening News showed last night and here are some links... http://www.cbsnews. com/stories/ 2009/04/28/ eveningnews/ main4975659. shtml http://www.webmd. com/brain/ autism/news/ 20090428/ gene-variants- hold-new- clues -to-autism .... the study¹s lead author was Hakon Hakonarson of Children's Hospital of Philadelphia. Interesting read. Caroline Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 29, 2009 Report Share Posted April 29, 2009 This extract from the Chicago Tribune article today and reprinted in the Schafer report might help ‘ One of the studies released Tuesday found that 65 percent of autistic participants shared a genetic variation between cadherin 10 and cadherin 9, a region of the genome that controls cell-adhesion molecules in the brain. The figure for study participants without autism was 60 percent -- a statistically notable difference. Cell-adhesion molecules help brain cells connect, and autism researchers have long suspected that trouble in this area may be linked to autism. " If we could remove this variant from the population, just take it away ... as much as 15 percent of autism would disappear, which is highly significant, " Hakonarson said. ‘ The 5 point difference between Autistic and non autistic represents 15 % - which they say is significant… I think it is notable, but not a significant difference a 5 point difference in any research can be masked by the margin of error. We need to look at the sample size and margin of error to determine the significance. I will try to look deeper into this to see what it is. _____ From: [mailto: ] On Behalf Of Jill Boyer Sent: Wednesday, April 29, 2009 12:15 PM Subject: Re: CBS Evening News I am confused, The CBS story stated that the mutation is in nearly 65 percent of the autistic population but the Autism Speaks website said that is in 15 percent of the population. Here is the link to the Autism Speaks website: http://www.autismsp <http://www.autismspeaks.org/press/autism_genes_discovered_chop.php.> eaks.org/press/autism_genes_discovered_chop.php. Either way, it is exciting but I have never seen a percentage as high as 65 percent. If that is accurate, this is really huge. Thank you for the links. All the best, Jill From: Caroline Glover <sfglovermac (DOT) <mailto:sfglover%40mac.com> com> Subject: Re: CBS Evening News groups (DOT) <mailto:%40> com Date: Wednesday, April 29, 2009, 1:03 PM I looked up the ³autism breakthrough² story that CBS Evening News showed last night and here are some links... http://www.cbsnews. com/stories/ 2009/04/28/ eveningnews/ main4975659. shtml http://www.webmd. com/brain/ autism/news/ 20090428/ gene-variants- hold-new- clues -to-autism .... the study¹s lead author was Hakon Hakonarson of Children's Hospital of Philadelphia. Interesting read. Caroline Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 30, 2009 Report Share Posted April 30, 2009 , This article discussed the numbers in the study a little bit... http://www.philly.com/inquirer/health_science/daily/20090429_CHOP__Penn_rese arch_points_to_genetic_link_in_autism.html Caroline Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 2, 2009 Report Share Posted May 2, 2009 Thanks for this Caroline - I'm getting the numbers checked out. It is curious - the study claims 65% of a sample of 2600 autistic children had these genetic anomolies, v's 60% of 7000 " normal " or not autistic children had the same anomolies. The variance being 5 points between the two - which is, according to my rudimentary statistics - not large. To get to " 15 % of autism is caused by these genetic malfunctions " then appears to be a bit of a stretch. The unanswered questions are what about the triggers into the dysfunction itself - ie - account for the 60% of normal kids who have the anomolies in there genes and are OK - and what about the rest. The article Caroline refers to in the Philly Enquirer is more revelaing than the heavily edited versions that appeared in Tribune owned papers - its worth reading - don't forget to complete the link by cutting an pasting the part that appeared on the second line below in black. R _____ From: [mailto: ] On Behalf Of Caroline Glover Sent: Thursday, April 30, 2009 12:51 PM Subject: Re: CBS Evening News , This article discussed the numbers in the study a little bit... http://www.philly. <http://www.philly.com/inquirer/health_science/daily/20090429_CHOP__Penn_res e> com/inquirer/health_science/daily/20090429_CHOP__Penn_rese arch_points_to_genetic_link_in_autism.html Caroline Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 3, 2009 Report Share Posted May 3, 2009 , Thanks for looking this.... it¹s been over 20 years since I took statistics and I don¹t know how to analyze the numbers properly. Caroline From: Crosss <crosswilsons@...> Reply-< > Date: Sat, 02 May 2009 19:45:12 -0700 < > Subject: RE: CBS Evening News Thanks for this Caroline - I'm getting the numbers checked out. Quote Link to comment Share on other sites More sharing options...
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