Re: Conflicting information on estrogen delivery methods- what do you think, ladies?

[Guest guest]

The way I have understood oral estrogen is that it adversely affects heart risk

factors such as Cardio-crp an inflammation marker, raises blood sugar level, and

increases binding hormone (in addition to the first pass thru the liver as you

mention) and found this to be true in my own blood tests while on oral.

>

> I always thought that transdermal methods are preferable to oral delivery- so

that estradiol can bypass the liver, and also to avoid the increase of the

binding hormone production (which makes estrogen unavailable), as well as the

impairment of the Growth Hormone production

(http://edrv.endojournals.org/content/25/5/693.full.)

>

> But I just came acros this article that promotes oral estrogen over

transdermal and states that only the oral estrogen affects cardiovascular

health(?!):

> http://www.worldlinkmedical.com/blog/transdermal-vs-oral-e2-estradiol/

>

> What's your take?

> Viki

>

[Guest guest]

The WHO study was flawed from my perspective...they used Premarin with or

without progestins..alll synthetics - they attributed the blood clots risk etc

to the Premarin they used (it was not done with bio-identical estradiol, from

what i remember)and actually, when looked at more closely, the premarin alone

was far less likley to be involved with any blood clot risks and problems of

that nature as when progestins were added.

> >

> > I always thought that transdermal methods are preferable to oral delivery-

so that estradiol can bypass the liver, and also to avoid the increase of the

binding hormone production (which makes estrogen unavailable), as well as the

impairment of the Growth Hormone production

(http://edrv.endojournals.org/content/25/5/693.full.)

> >

> > But I just came acros this article that promotes oral estrogen over

transdermal and states that only the oral estrogen affects cardiovascular

health(?!):

> > http://www.worldlinkmedical.com/blog/transdermal-vs-oral-e2-estradiol/

> >

> > What's your take?

> > Viki

> >

>

[Guest guest]

In the WHI the Premarin/progestin group slightly, but significantly,

increased the breast cancer risk. The Premarin only risk slightly, but not

significantly, decreased the BC risk. The study of women just on Premarin

was stopped because of the increased stroke incidence. I don't know of any

studies of stroke risk with transdermal bioidentical vs oral bioidentical.

I didn't read all the references at the bottom of the article. Too bad

there were no links. I have often read articles with citations but upon

reading the citations, the article's conclusions could not be supported.

That was how the late Lee's website was in radically promoting

progesterone cream. I wouldn't draw any conclusions without reading all

those supporting references.

Val

-----Original Message-----

From: rhythmicliving [mailto:rhythmicliving ]

On Behalf Of astrodiana

The WHO study was flawed from my perspective...they used Premarin with or

without progestins..alll synthetics - they attributed the blood clots risk

etc to the Premarin they used (it was not done with bio-identical estradiol,

from what i remember)and actually, when looked at more closely, the premarin

alone was far less likley to be involved with any blood clot risks and

problems of that nature as when progestins were added.

> >

> > I always thought that transdermal methods are preferable to oral

delivery- so that estradiol can bypass the liver, and also to avoid the

increase of the binding hormone production (which makes estrogen

unavailable), as well as the impairment of the Growth Hormone production

(http://edrv.endojournals.org/content/25/5/693.full.)

> >

> > But I just came acros this article that promotes oral estrogen over

transdermal and states that only the oral estrogen affects cardiovascular

health(?!):

> > http://www.worldlinkmedical.com/blog/transdermal-vs-oral-e2-estradiol/

> >

> > What's your take?

[Guest guest]

Hi Val,Not quite on topic…For some reason Yahoo is re-setting my access to 'groups' and I can't see past posts!Where did you say you bought your estrogen? I know there is a pharmacy people use by mail order (was it masters or something?) which has better rates on patches, etc. I'm going to be in the states soon and thought I would get more. I've been using a combination of patches and estrodial in olive oil.ThanksNoraReply-To: <rhythmicliving >Date: Sun, 20 May 2012 08:52:59 -0600To: <rhythmicliving >Subject: RE: Re: Conflicting information on estrogen delivery methods- what do you think, ladies?

In the WHI the Premarin/progestin group slightly, but significantly,

increased the breast cancer risk. The Premarin only risk slightly, but not

significantly, decreased the BC risk. The study of women just on Premarin

was stopped because of the increased stroke incidence. I don't know of any

studies of stroke risk with transdermal bioidentical vs oral bioidentical.

I didn't read all the references at the bottom of the article. Too badthere were no links. I have often read articles with citations but upon

reading the citations, the article's conclusions could not be supported.

That was how the late Lee's website was in radically promoting

progesterone cream. I wouldn't draw any conclusions without reading all

those supporting references.

Val

-----Original Message-----

From: rhythmicliving [mailto:rhythmicliving ]

On Behalf Of astrodiana

The WHO study was flawed from my perspective...they used Premarin with or

without progestins..alll synthetics - they attributed the blood clots risk

etc to the Premarin they used (it was not done with bio-identical estradiol,

from what i remember)and actually, when looked at more closely, the premarin

alone was far less likley to be involved with any blood clot risks and

problems of that nature as when progestins were added.

> >

> > I always thought that transdermal methods are preferable to oral

delivery- so that estradiol can bypass the liver, and also to avoid theincrease of the binding hormone production (which makes estrogen

unavailable), as well as the impairment of the Growth Hormone production

(http://edrv.endojournals.org/content/25/5/693.full.)

> >

> > But I just came acros this article that promotes oral estrogen over

transdermal and states that only the oral estrogen affects cardiovascular

health(?!):

> > http://www.worldlinkmedical.com/blog/transdermal-vs-oral-e2-estradiol/

> >

> > What's your take?

[Guest guest]

Nora, I get my Oestrogel from Masters Marketing in the UK. You need a prescription. I'm in the U.S. Val From: rhythmicliving [mailto:rhythmicliving ] On Behalf Of Nora RothrockHi Val, Where did you say you bought your estrogen? I know there is a pharmacy people use by mail order (was it masters or something?) which has better rates on patches, etc. I'm going to be in the states soon and thought I would get more. I've been using a combination of patches and estrodial in olive oil. Thanks Nora

[Guest guest]

Thanks Val!I'll be in the US for a couple of weeks so I'm hoping this saves me some money.NoraReply-To: <rhythmicliving >Date: Sun, 20 May 2012 19:52:19 -0600To: <rhythmicliving >Subject: RE: Re: Conflicting information on estrogen delivery methods- what do you think, ladies?

Nora, I get my Oestrogel from Masters Marketing in the UK. You need a prescription. I'm in the U.S. Val From: rhythmicliving [mailto:rhythmicliving ] On Behalf Of Nora RothrockHi Val, <

/p>Where did you say you bought your estrogen? I know there is a pharmacy people use by mail order (was it masters or something?) which has better rates on patches, etc. I'm going to be in the states soon and thought I would get more. I've been using a combination of patches and estrodial in olive oil. Thanks Nora

[Guest guest]

Back when I was concerned about contamination with my youngest son I used oral E

and also watched things like C reactive protein. The oral E was various forms

of hell for me and working with the pediatric doc to make sure the kiddo was ok,

I went back to transdermal E. Now I wouldn't give a flip if 10,000

Frenchwomen were skinny and happy on oral E .... I'm not touching the stuff.

(-:

Laurel

> I always thought that transdermal methods are preferable to oral delivery- so

that estradiol can bypass the liver, and also to avoid the increase of the

binding hormone production (which makes estrogen unavailable), as well as the

impairment of the Growth Hormone production

(http://edrv.endojournals.org/content/25/5/693.full.)

>

> But I just came acros this article that promotes oral estrogen over

transdermal and states that only the oral estrogen affects cardiovascular

health(?!):

> http://www.worldlinkmedical.com/blog/transdermal-vs-oral-e2-estradiol/

>

> What's your take?

> Viki

>

>

>

> ------------------------------------

>

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>

> **The group conversation is informational in nature and is not intended as

medical advice.**