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There is the NNY Autism Center...we went there from Chicago and we love them!

315-773-5405

www.nnyautismcenter.com

- :)

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>

> From: natasa778 <neno@...>

> Subject: Chronic Fatigue and Prostate Cancer: A Retroviral Connection -

more details

>

> Date: Thursday, October 22, 2009, 10:06 AM

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>  

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>

>

> more details on the story

> " ...transmission can occur via bodily fluids, including saliva... " if

> something like this the case in autism, it would explain the clustering

> of cases amongst staff in that autism school... It would also be easily

> passed through placenta? - explaining mums with CFS and kids developing

> ASD after vaccination (immune stressors reactivate retroviruses)

>

> Chronic Fatigue and Prostate Cancer: A Retroviral Connection? Sam Kean

> As if chronic fatigue syndrome (CFS) hasn't caused enough brawls, a new

> study published online by Science

> (www.sciencemag. org/cgi/content/ abstract/ 1179052

> <http://www.sciencem ag.org/cgi/ content/abstract /1179052> ) links the

> disease to a possibly contagious rodent retrovirus, XMRV, which has also

> been implicated in an aggressive form of prostate cancer. Related work

> by the authors also suggests that CFS might best be treated with AIDS

> drugs. Even the lead author, Judy Mikovits of the Whittemore

> Institute for Neuro-Immune Disease in Reno, Nevada, says she understands

> why linking CFS to a retrovirus and to prostate cancer has already drawn

> skepticism.

>

> In 2006, an unrelated paper found an association between XMRV, which

> originated in mice, and a deadly prostate cancer exacerbated by a

> deficient enzyme. Mikovits and colleagues had seen the same deficiency

> in CFS cases. When they investigated further, the team discovered XMRV

> in the white blood cells of two-thirds of CFS patients but only 4% of

> control subjects. Intriguingly, Mikovits says XMRV does major damage in

> natural killer (NK) blood cells, which attack tumor cells and cells

> infected by viruses, and other studies suggest people with CFS suffer

> from high rates of cancer. Unpublished work, Mikovits adds, has found

> blood serum antibodies for XMRV in 95% of CFS patients.

>

> [Figure 1]

> <http://www.sciencem ag.org/cgi/ content/full/ 326/5950/ 215-a/F1>

>

> Controversial link. A study of chronic fatigue syndrome points to a

> retrovirus found in cancerous prostate cells (magnified in inset).

> CREDIT: ROBERT SCHLABERG AND HARSH THAKER

>

> [Larger version of this image]

> <http://www.sciencem ag.org/cgi/ content/full/ 326/5950/ 215-a/F1>

> All previous attempts to nail down a cause for CFS†" including many

> links to viral infections†" have foundered or been retracted, and many

> doctors remain doubtful that it's a coherent disease. Mikovits says her

> work " proves beyond a shadow of a doubt that CFS is a real disease. " But

> some of her peers find the report of a viral link premature.

>

> ph DeRisi, a molecular biologist at the University of California,

> San Francisco, who co-discovered XMRV, was not satisfied with details in

> the paper: He wanted to know more about the viral load in CFS patients

> and how the demographics of the control group matched that of CFS

> patients. And the Mikovits team didn't do enough to rule out

> contamination, he says. " One has to be very careful about making claims

> about such a sensitive and emotionally charged issue as CFS, where many

> claims have been made in the past. " At the least, a double-blind study

> where a third-party lab searches for XMRV in CFS patients and in

> controls is vital, he says.

>

> Other CFS specialists, including Kerr at St. 's

> University of London, are convinced that the Mikovits team discovered

> something important. " The fact that the virus was actually grown from

> the blood cells of CFS patients strongly suggests some sort of role in

> the pathogenesis of the disease. " But exactly what they discovered

> remains unclear, given that the group is not claiming to have identified

> a cause.

>

> Coffin, a molecular biologist at Tufts University in Boston,

> analyzed the Mikovits paper in a separate " Perspective " also published

> online by Science (www.sciencemag. org/cgi/content/ abstract/ 1181349

> <http://www.sciencem ag.org/cgi/ content/abstract /1181349> ). Coffin was

> highly skeptical of the paper at first, but the team found enough

> independent lines of evidence for XMRV to convert him. " They will be

> celebrating in the clinics where these people [with CFS] are being

> treated, " he now says.

> Even if the finding of a link to XMRV holds up, treatment suggestions

> are bound to attract controversy. No one knows how easily XMRV spreads,

> although Mikovits says transmission can occur via bodily fluids,

> including saliva. Mikovits also says unpublished preclinical data hints

> that scientists can treat XMRV with AIDS drugs such as AZT, although AZT

> itself might prove too toxic. Kerr remained cautious about this: " With

> present public knowledge†" what is described in this paper†" further

> work would be necessary before antiretroviral drugs could be

> recommended. "

>

>

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