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This from 1992, could not find updates...

http://gateway.nlm.nih.gov/MeetingAbstracts/ma?f=102202033.html

J Pineal Res. 2008 May;44(4):373-8.

Regression of herpes viral infection symptoms using melatonin and SB-73:

comparison with Acyclovir.

Nunes Oda S, Pereira Rde S.Universidade Federal de São , Departamento

de Fisioterapia, Dr. Nivaldo's laboratory, Rod. Washington Luís, São ,

SP, Brazil.

Infection with Herpes simplex virus type 1 (HSV-1) typically causes lesions

of the mouth, face, skin, esophagus, or brain. Herpes simplex virus type 2

(HSV-2) usually causes infections of the genitals, rectum, skin, hands, or

meninges. The herpes viruses are a major cause of blindness from keratitis.

The usual drugs used for herpes are Vidarabine, Acyclovir, Penciclovir and

Ganciclovir; they are associated with several complications. The aim of this

study was to investigate if a formulation containing 2.5 mg melatonin and

100 mg SB-73 would help patients with herpes, and to compare the preparation

with 200 mg Acyclovir. SB-73 is a mixture of magnesium, phosphate, fatty

acids extracted from Aspergillus sp. which has anti-herpes virus properties.

A single blind randomized study was performed in which 70 patients underwent

treatment using the supplement cited above (group A) and 75 received

treatment of 200 mg Acyclovir (group B). Sixty-seven patients of the group A

(95.7%) reported a complete regression of symptoms after 7 days of

treatment. By comparison, 64 subjects (85.3%) of the Acyclovir reported

regression of symptoms in the same period. There was statiscally significant

difference between the groups (P < 0.05).

PMID: 18410585

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