Guest guest Posted January 16, 2010 Report Share Posted January 16, 2010 From http://www.hhv-6foundation.org/testing.html .....PCR DNA tests can detect HHV-6 in the serum during primary roseola infections and in acute transplant reactivations, but they cannot determine reliably if a patient has a chronic central nervous system (CNS) infection that has reactivated , because there is so little virus circulating outside of the tissues. HHV-6A & B viruses (especially HHV-6A) migrate to the central nervous system and other organs and away from the bloodstream. HHV-6A has been found to persist in the spinal fluid long after it has disappeared from the plasma. 3 Researchers at the NINDS have determined from autopsy that bone marrow transplant patients with active or reactivated infections in the CNS tissue have very little HHV-6 in the spinal fluid or serum.4This means that if the HHV-6 is chronically active in the brain tissue, it may be impossible to find any evidence of it in the peripheral blood or even the spinal fluid As is the case with pathogens with low viral copy numbers such as HHV-8 and West Nile Virus, indirect evidence of the HHV-6 antibodies are easier to find than the HHV-6 virus itself. Therefore elevated IgG antibody levels (above a threshold) may be the only indication of a reactivated chronic HHV-6 CNS infection... I've posted this type of question to Judy M for the 22nd Q & A session, I do hope she picks it, but it would help if more people wrote in as this could be crucial for autism... Natasa Quote Link to comment Share on other sites More sharing options...
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