Guest guest Posted January 4, 2011 Report Share Posted January 4, 2011 As far as my research Valtrex is a next generation of the same active ingredient as Acyclovir, We were on Valtrex but my son's tiers never came down until we switched to Acyclovir. Taking it five times a day made the difference. bill ________________________________ From: Buckley <stephaniejbuckley@...> nids ; neuroimmune-xmrv-alliance Sent: Tue, January 4, 2011 4:54:58 PM Subject: Valtrex//Valacyclvir/Acyclovir Hello, Can someone please explain to me the difference in these anit-virals? My boys are on Valacyclovir and doing pretty good BUT I wonder if Valtrex itself or Acyclovir would be better. My oldest gets cold sores and in the past has been given valtrex for an outbreak. It clears it up almost immediately however on the Valacyclivir he still gets the cold sores...Is it not as strong? Thanks, Steph Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 4, 2011 Report Share Posted January 4, 2011 Valacyclovir (Valtrex) and we can include Famcyclovir (FamVir) in this discussion - both often prescribed by Dr Goldberg are more complex versions of Acyclovir - they both pass through the gut into the bloodstream and are metabolised in the liver to produce acyclovir. Acyclovir (Zovirax) is metabolised more in the gut and a lot passes through the system before reaching the bloodstream - that is why the doses are higher and taken more often during the day - this is my rudimentary understanding. FamVir and Valtrex can cause spikes in liver enzyme levels, which is one reason why Dr G routinely checks these in bloodwork. My son would not tolerate Valtrex that well, but did so FamVir - which we have used for over ten years, though we are now using Acyclovir for the second time - it seems slightly more effective - its just a pain have to take it 5 x instead of 3x. _____ From: [mailto: ] On Behalf Of Bill klimas Sent: Tuesday, January 04, 2011 3:59 PM Subject: Re: Valtrex//Valacyclvir/Acyclovir As far as my research Valtrex is a next generation of the same active ingredient as Acyclovir, We were on Valtrex but my son's tiers never came down until we switched to Acyclovir. Taking it five times a day made the difference. bill ________________________________ From: Buckley <stephaniejbuckley@... <mailto:stephaniejbuckley%40hotmail.com> > nids <mailto:nids%40> ; neuroimmune-xmrv-alliance <mailto:neuroimmune-xmrv-alliance%40> Sent: Tue, January 4, 2011 4:54:58 PM Subject: Valtrex//Valacyclvir/Acyclovir Hello, Can someone please explain to me the difference in these anit-virals? My boys are on Valacyclovir and doing pretty good BUT I wonder if Valtrex itself or Acyclovir would be better. My oldest gets cold sores and in the past has been given valtrex for an outbreak. It clears it up almost immediately however on the Valacyclivir he still gets the cold sores...Is it not as strong? Thanks, Steph Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 4, 2011 Report Share Posted January 4, 2011 Valacyclovir is the generic for Vlatrex.........same thing just differnt price. Acyclovir is a bit different.....not sure exactly but I think it is a bit less strong. You can google it and find out. There is also another herpes anti viral called FAMVIR.  People often find one works and another does not or one works for awhile and then they need to switch......all are good it's just trial and error for you.  From: Buckley <stephaniejbuckley@...> Subject: Valtrex//Valacyclvir/Acyclovir nids , neuroimmune-xmrv-alliance Date: Tuesday, January 4, 2011, 4:54 PM  Hello, Can someone please explain to me the difference in these anit-virals? My boys are on Valacyclovir and doing pretty good BUT I wonder if Valtrex itself or Acyclovir would be better. My oldest gets cold sores and in the past has been given valtrex for an outbreak. It clears it up almost immediately however on the Valacyclivir he still gets the cold sores...Is it not as strong? Thanks, Steph Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 4, 2011 Report Share Posted January 4, 2011 I was surprised to see your son has been using antivirals for SO many years. Is he unable to keep his titers down without them, or what is the reasoning behind such prolonged use? Thanks, Dawn Sent from my iPad On Jan 4, 2011, at 7:14 PM, " Crosss " <crosswilsons@...> wrote: Valacyclovir (Valtrex) and we can include Famcyclovir (FamVir) in this discussion - both often prescribed by Dr Goldberg are more complex versions of Acyclovir - they both pass through the gut into the bloodstream and are metabolised in the liver to produce acyclovir. Acyclovir (Zovirax) is metabolised more in the gut and a lot passes through the system before reaching the bloodstream - that is why the doses are higher and taken more often during the day - this is my rudimentary understanding. FamVir and Valtrex can cause spikes in liver enzyme levels, which is one reason why Dr G routinely checks these in bloodwork. My son would not tolerate Valtrex that well, but did so FamVir - which we have used for over ten years, though we are now using Acyclovir for the second time - it seems slightly more effective - its just a pain have to take it 5 x instead of 3x. _____ From: [mailto: ] On Behalf Of Bill klimas Sent: Tuesday, January 04, 2011 3:59 PM Subject: Re: Valtrex//Valacyclvir/Acyclovir As far as my research Valtrex is a next generation of the same active ingredient as Acyclovir, We were on Valtrex but my son's tiers never came down until we switched to Acyclovir. Taking it five times a day made the difference. bill ________________________________ From: Buckley <stephaniejbuckley@... <mailto:stephaniejbuckley%40hotmail.com> > nids <mailto:nids%40> ; neuroimmune-xmrv-alliance <mailto:neuroimmune-xmrv-alliance%40> Sent: Tue, January 4, 2011 4:54:58 PM Subject: Valtrex//Valacyclvir/Acyclovir Hello, Can someone please explain to me the difference in these anit-virals? My boys are on Valacyclovir and doing pretty good BUT I wonder if Valtrex itself or Acyclovir would be better. My oldest gets cold sores and in the past has been given valtrex for an outbreak. It clears it up almost immediately however on the Valacyclivir he still gets the cold sores...Is it not as strong? Thanks, Steph Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 5, 2011 Report Share Posted January 5, 2011 I believe Valtrex is converted into Acyclovir by the liver, that that's the main difference? ________________________________ From: Bill klimas <klimas_bill@...> Sent: Tue, January 4, 2011 5:58:31 PM Subject: Re: Valtrex//Valacyclvir/Acyclovir  As far as my research Valtrex is a next generation of the same active ingredient as Acyclovir, We were on Valtrex but my son's tiers never came down until we switched to Acyclovir. Taking it five times a day made the difference. bill ________________________________ From: Buckley <stephaniejbuckley@...> nids ; neuroimmune-xmrv-alliance Sent: Tue, January 4, 2011 4:54:58 PM Subject: Valtrex//Valacyclvir/Acyclovir Hello, Can someone please explain to me the difference in these anit-virals? My boys are on Valacyclovir and doing pretty good BUT I wonder if Valtrex itself or Acyclovir would be better. My oldest gets cold sores and in the past has been given valtrex for an outbreak. It clears it up almost immediately however on the Valacyclivir he still gets the cold sores...Is it not as strong? Thanks, Steph Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 5, 2011 Report Share Posted January 5, 2011 Ooh you were much better at that explanation. Thanks! ________________________________ From: Crosss <crosswilsons@...> Sent: Tue, January 4, 2011 7:14:37 PM Subject: RE: Valtrex//Valacyclvir/Acyclovir  Valacyclovir (Valtrex) and we can include Famcyclovir (FamVir) in this discussion - both often prescribed by Dr Goldberg are more complex versions of Acyclovir - they both pass through the gut into the bloodstream and are metabolised in the liver to produce acyclovir. Acyclovir (Zovirax) is metabolised more in the gut and a lot passes through the system before reaching the bloodstream - that is why the doses are higher and taken more often during the day - this is my rudimentary understanding. FamVir and Valtrex can cause spikes in liver enzyme levels, which is one reason why Dr G routinely checks these in bloodwork. My son would not tolerate Valtrex that well, but did so FamVir - which we have used for over ten years, though we are now using Acyclovir for the second time - it seems slightly more effective - its just a pain have to take it 5 x instead of 3x. _____ From: [mailto: ] On Behalf Of Bill klimas Sent: Tuesday, January 04, 2011 3:59 PM Subject: Re: Valtrex//Valacyclvir/Acyclovir As far as my research Valtrex is a next generation of the same active ingredient as Acyclovir, We were on Valtrex but my son's tiers never came down until we switched to Acyclovir. Taking it five times a day made the difference. bill ________________________________ From: Buckley <stephaniejbuckley@... <mailto:stephaniejbuckley%40hotmail.com> > nids <mailto:nids%40> ; neuroimmune-xmrv-alliance <mailto:neuroimmune-xmrv-alliance%40> Sent: Tue, January 4, 2011 4:54:58 PM Subject: Valtrex//Valacyclvir/Acyclovir Hello, Can someone please explain to me the difference in these anit-virals? My boys are on Valacyclovir and doing pretty good BUT I wonder if Valtrex itself or Acyclovir would be better. My oldest gets cold sores and in the past has been given valtrex for an outbreak. It clears it up almost immediately however on the Valacyclivir he still gets the cold sores...Is it not as strong? Thanks, Steph Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 5, 2011 Report Share Posted January 5, 2011 I was surprised to see your son has been using antivirals for SO many years. Is he unable to keep his titers down without them, or what is the reasoning behind such prolonged use? Thanks, Dawn > > Valacyclovir (Valtrex) and we can include Famcyclovir (FamVir) in this > discussion - both often prescribed by Dr Goldberg are more complex versions > of Acyclovir - they both pass through the gut into the bloodstream and are > metabolised in the liver to produce acyclovir. > > Acyclovir (Zovirax) is metabolised more in the gut and a lot passes through > the system before reaching the bloodstream - that is why the doses are > higher and taken more often during the day - this is my rudimentary > understanding. > > FamVir and Valtrex can cause spikes in liver enzyme levels, which is one > reason why Dr G routinely checks these in bloodwork. My son would not > tolerate Valtrex that well, but did so FamVir - which we have used for over > ten years, though we are now using Acyclovir for the second time - it seems > slightly more effective - its just a pain have to take it 5 x instead of 3x. > > > > > _____ > > From: [mailto: ] On Behalf Of Bill > klimas > Sent: Tuesday, January 04, 2011 3:59 PM > > Subject: Re: Valtrex//Valacyclvir/Acyclovir > > > > > > As far as my research Valtrex is a next generation of the same active > ingredient > as Acyclovir, We were on Valtrex but my son's tiers never came down until we > > switched to Acyclovir. Taking it five times a day made the difference. > bill > > ________________________________ > From: Buckley <stephaniejbuckley@... > <mailto:stephaniejbuckley%40hotmail.com> > > nids <mailto:nids%40> ; > neuroimmune-xmrv-alliance > <mailto:neuroimmune-xmrv-alliance%40> > Sent: Tue, January 4, 2011 4:54:58 PM > Subject: Valtrex//Valacyclvir/Acyclovir > > Hello, > > Can someone please explain to me the difference in these anit-virals? My > boys > are on Valacyclovir and doing pretty good BUT I wonder if Valtrex itself or > Acyclovir would be better. My oldest gets cold sores and in the past has > been > given valtrex for an outbreak. It clears it up almost immediately however on > > the Valacyclivir he still gets the cold sores...Is it not as strong? > > Thanks, > > Steph > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 5, 2011 Report Share Posted January 5, 2011 HHV - 6 is way down - and mostly always negative, but CMV and EBV are often very difficult to bring down. Many kids/teens and young adults who are recovered still use an antiviral (and have done so for a lot longer than my son) to keep their system in check - if they stop I am told, cognitive function can suffer some. Antivirals assist in 'cooling' the immune system - they are not a cure. As I understand it, many people with CFS use them longer term as well. If we could get immune modulating medicines into trial, and approved, we might have a shot and getting the immune system into better shape, and reduce the reliance on antivirals. R _____ From: [mailto: ] On Behalf Of Dawn Sent: Tuesday, January 04, 2011 6:42 PM Subject: Re: Valtrex//Valacyclvir/Acyclovir I was surprised to see your son has been using antivirals for SO many years. Is he unable to keep his titers down without them, or what is the reasoning behind such prolonged use? Thanks, Dawn Sent from my iPad On Jan 4, 2011, at 7:14 PM, " Crosss " <crosswilsons@... <mailto:crosswilsons%40socal.rr.com> > wrote: Valacyclovir (Valtrex) and we can include Famcyclovir (FamVir) in this discussion - both often prescribed by Dr Goldberg are more complex versions of Acyclovir - they both pass through the gut into the bloodstream and are metabolised in the liver to produce acyclovir. Acyclovir (Zovirax) is metabolised more in the gut and a lot passes through the system before reaching the bloodstream - that is why the doses are higher and taken more often during the day - this is my rudimentary understanding. FamVir and Valtrex can cause spikes in liver enzyme levels, which is one reason why Dr G routinely checks these in bloodwork. My son would not tolerate Valtrex that well, but did so FamVir - which we have used for over ten years, though we are now using Acyclovir for the second time - it seems slightly more effective - its just a pain have to take it 5 x instead of 3x. _____ From: <mailto:%40> [mailto: <mailto:%40> ] On Behalf Of Bill klimas Sent: Tuesday, January 04, 2011 3:59 PM <mailto:%40> Subject: Re: Valtrex//Valacyclvir/Acyclovir As far as my research Valtrex is a next generation of the same active ingredient as Acyclovir, We were on Valtrex but my son's tiers never came down until we switched to Acyclovir. Taking it five times a day made the difference. bill ________________________________ From: Buckley <stephaniejbuckley@... <mailto:stephaniejbuckley%40hotmail.com> <mailto:stephaniejbuckley%40hotmail.com> > nids <mailto:nids%40> <mailto:nids%40> ; neuroimmune-xmrv-alliance <mailto:neuroimmune-xmrv-alliance%40> <mailto:neuroimmune-xmrv-alliance%40> Sent: Tue, January 4, 2011 4:54:58 PM Subject: Valtrex//Valacyclvir/Acyclovir Hello, Can someone please explain to me the difference in these anit-virals? My boys are on Valacyclovir and doing pretty good BUT I wonder if Valtrex itself or Acyclovir would be better. My oldest gets cold sores and in the past has been given valtrex for an outbreak. It clears it up almost immediately however on the Valacyclivir he still gets the cold sores...Is it not as strong? Thanks, Steph Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 7, 2011 Report Share Posted January 7, 2011 Keeping the viruses suppressed, because they have a lot of modulating effects on a dysfunctioning immune system. This illness can last a very long time. Compare to CFS, I've been ill w/varying levels of functioning since 1983. With my PANDAS problems, I've been having strep problems (this time around) since 2003. Stopping, starting, or under-dosing (using maintenance doses instead of treatment doses) of antivirals is worse than stopping & starting in a chronic illness, because several of the viruses can build a resistance very quickly as soon as you miss a few doses, and there aren't very many to choose from. Same with an antifungal. We stay on those long term at higher doses as well, cycling them according to which kind, regularly to prevent resistance. This is learned from some top AIDS researchers. You don't let up on these viruses. And now as we wait for info on XMRV studies, what we've been doing based on a paradigm is really starting to make even more sense. HTH ________________________________ From: Dawn <oufan247@...> " " < > Sent: Tue, January 4, 2011 8:41:58 PM Subject: Re: Valtrex//Valacyclvir/Acyclovir  I was surprised to see your son has been using antivirals for SO many years. Is he unable to keep his titers down without them, or what is the reasoning behind such prolonged use? Thanks, Dawn Sent from my iPad On Jan 4, 2011, at 7:14 PM, " Crosss " <crosswilsons@...> wrote: Valacyclovir (Valtrex) and we can include Famcyclovir (FamVir) in this discussion - both often prescribed by Dr Goldberg are more complex versions of Acyclovir - they both pass through the gut into the bloodstream and are metabolised in the liver to produce acyclovir. Acyclovir (Zovirax) is metabolised more in the gut and a lot passes through the system before reaching the bloodstream - that is why the doses are higher and taken more often during the day - this is my rudimentary understanding. FamVir and Valtrex can cause spikes in liver enzyme levels, which is one reason why Dr G routinely checks these in bloodwork. My son would not tolerate Valtrex that well, but did so FamVir - which we have used for over ten years, though we are now using Acyclovir for the second time - it seems slightly more effective - its just a pain have to take it 5 x instead of 3x. _____ From: [mailto: ] On Behalf Of Bill klimas Sent: Tuesday, January 04, 2011 3:59 PM Subject: Re: Valtrex//Valacyclvir/Acyclovir As far as my research Valtrex is a next generation of the same active ingredient as Acyclovir, We were on Valtrex but my son's tiers never came down until we switched to Acyclovir. Taking it five times a day made the difference. bill ________________________________ From: Buckley <stephaniejbuckley@... <mailto:stephaniejbuckley%40hotmail.com> > nids <mailto:nids%40> ; neuroimmune-xmrv-alliance <mailto:neuroimmune-xmrv-alliance%40> Sent: Tue, January 4, 2011 4:54:58 PM Subject: Valtrex//Valacyclvir/Acyclovir Hello, Can someone please explain to me the difference in these anit-virals? My boys are on Valacyclovir and doing pretty good BUT I wonder if Valtrex itself or Acyclovir would be better. My oldest gets cold sores and in the past has been given valtrex for an outbreak. It clears it up almost immediately however on the Valacyclivir he still gets the cold sores...Is it not as strong? Thanks, Steph Quote Link to comment Share on other sites More sharing options...
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