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Re: Neuropeptide Y

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She presented this at a confrence in 2008 maybe 09. I will see if I can find it.

Bill

________________________________

From: <thecolemans4@...>

< >

Sent: Thu, January 13, 2011 7:29:29 PM

Subject: Neuropeptide Y

Excerpted from CFIDS Association of America newsletter:

Researchers at University of Miami and University of Alberta published data

comparing levels of neuropeptide Y (NPY) in plasma samples taken from 93 CFS

patients, 100 healthy sedentary controls and 37 individuals with Gulf War

Illness. NPY levels in CFS patients were higher than in either control group.

Levels also correlated with some symptom severity measures, providing the

potential for NPY to be used as a biomarker for CFS. The authors state that this

data added to other information supports dysregulation of the

hypothalamic-pituitary-adrenal axis in CFS, possibly due to infection. This

study was funded in part by the CFIDS Association through a grant made in 2006.

(Behavioral and Brain Functions)

This is one of the biomarkers Bill mentioned that Dr Klimas's group has been

working on.

Sure would love to get a copy of that study .... anyone seen it?

Thanks,

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Found something...

http://www.behavioralandbrainfunctions.com/content/6/1/76

________________________________

From: Bill klimas <klimas_bill@...>

Sent: Fri, January 14, 2011 4:47:24 AM

Subject: Re: Neuropeptide Y

 

She presented this at a confrence in 2008 maybe 09. I will see if I can find it.

Bill

________________________________

From: <thecolemans4@...>

< >

Sent: Thu, January 13, 2011 7:29:29 PM

Subject: Neuropeptide Y

Excerpted from CFIDS Association of America newsletter:

Researchers at University of Miami and University of Alberta published data

comparing levels of neuropeptide Y (NPY) in plasma samples taken from 93 CFS

patients, 100 healthy sedentary controls and 37 individuals with Gulf War

Illness. NPY levels in CFS patients were higher than in either control group.

Levels also correlated with some symptom severity measures, providing the

potential for NPY to be used as a biomarker for CFS. The authors state that this

data added to other information supports dysregulation of the

hypothalamic-pituitary-adrenal axis in CFS, possibly due to infection. This

study was funded in part by the CFIDS Association through a grant made in 2006.

(Behavioral and Brain Functions)

This is one of the biomarkers Bill mentioned that Dr Klimas's group has been

working on.

Sure would love to get a copy of that study .... anyone seen it?

Thanks,

Link to comment
Share on other sites

That is the paper. The lead author, ann Fletcher is 's partner and the

director of the immunology Lab at U of M.

________________________________

From: <thecolemans4@...>

Sent: Fri, January 14, 2011 3:30:52 PM

Subject: Re: Neuropeptide Y

Found something...

http://www.behavioralandbrainfunctions.com/content/6/1/76

________________________________

From: Bill klimas <klimas_bill@...>

Sent: Fri, January 14, 2011 4:47:24 AM

Subject: Re: Neuropeptide Y

She presented this at a confrence in 2008 maybe 09. I will see if I can find it.

Bill

________________________________

From: <thecolemans4@...>

< >

Sent: Thu, January 13, 2011 7:29:29 PM

Subject: Neuropeptide Y

Excerpted from CFIDS Association of America newsletter:

Researchers at University of Miami and University of Alberta published data

comparing levels of neuropeptide Y (NPY) in plasma samples taken from 93 CFS

patients, 100 healthy sedentary controls and 37 individuals with Gulf War

Illness. NPY levels in CFS patients were higher than in either control group.

Levels also correlated with some symptom severity measures, providing the

potential for NPY to be used as a biomarker for CFS. The authors state that this

data added to other information supports dysregulation of the

hypothalamic-pituitary-adrenal axis in CFS, possibly due to infection. This

study was funded in part by the CFIDS Association through a grant made in 2006.

(Behavioral and Brain Functions)

This is one of the biomarkers Bill mentioned that Dr Klimas's group has been

working on.

Sure would love to get a copy of that study .... anyone seen it?

Thanks,

Link to comment
Share on other sites

Hmmm. Reading about neuropeptide Y (wow my OCD really is down considering I

haven't read everything on the web about it yet - I need to get my ASO checked -

either that or I love Amantadine lol) ...

It seems like having this as a marker - at least for a time - is really going

to

reinforce the whole stress-reaction paradigm of CFS until more studies are

available to show how infections can increase it.  Obviously they can - it's

mentioned in their paper...   So I'll keep looking for it. Surely they're

out

there. I read in one place where they could inject it directly into the

hypothalmus and cause an acute corticotropin-hormone release in the rat

brain...

I'll have to look, but I think that's one of the stress hormones.  I wonder if

it's one of the hormones found to feed XMRV that Dr Mikovitz commented on

somewhere?

Just a thought.

 

________________________________

From: Bill klimas <klimas_bill@...>

Sent: Fri, January 14, 2011 4:36:09 PM

Subject: Re: Neuropeptide Y

 

That is the paper. The lead author, ann Fletcher is 's partner and the

director of the immunology Lab at U of M.

________________________________

From: <thecolemans4@...>

Sent: Fri, January 14, 2011 3:30:52 PM

Subject: Re: Neuropeptide Y

Found something...

http://www.behavioralandbrainfunctions.com/content/6/1/76

________________________________

From: Bill klimas <klimas_bill@...>

Sent: Fri, January 14, 2011 4:47:24 AM

Subject: Re: Neuropeptide Y

She presented this at a confrence in 2008 maybe 09. I will see if I can find it.

Bill

________________________________

From: <thecolemans4@...>

< >

Sent: Thu, January 13, 2011 7:29:29 PM

Subject: Neuropeptide Y

Excerpted from CFIDS Association of America newsletter:

Researchers at University of Miami and University of Alberta published data

comparing levels of neuropeptide Y (NPY) in plasma samples taken from 93 CFS

patients, 100 healthy sedentary controls and 37 individuals with Gulf War

Illness. NPY levels in CFS patients were higher than in either control group.

Levels also correlated with some symptom severity measures, providing the

potential for NPY to be used as a biomarker for CFS. The authors state that this

data added to other information supports dysregulation of the

hypothalamic-pituitary-adrenal axis in CFS, possibly due to infection. This

study was funded in part by the CFIDS Association through a grant made in 2006.

(Behavioral and Brain Functions)

This is one of the biomarkers Bill mentioned that Dr Klimas's group has been

working on.

Sure would love to get a copy of that study .... anyone seen it?

Thanks,

Link to comment
Share on other sites

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