Guest guest Posted November 24, 2010 Report Share Posted November 24, 2010  http://cfsuntied.com/blog2/2010/11/23/dr-singhs-xmrv-patents-ground-shaking-reve\ lations/ Dr. Ila Singh is a retrovirologist from the University of Utah who has been working on research into XMRV. She recently filed patents on November 18th and it is a very dense and difficult read for a lay person but there are some important revelations that have been shared from people who read through this, including: 25% OF BREAST CANCERS CONTAINED XMRV! …. 178 cases of breast cancer were examined for the presence of XMRV using the described methods. Approximately 25% of breast cancers contained either XMRV proviral DNA sequences or XMRV proteins. The XMRV proteins were seen exclusively in the malignant breast epithelium (Figure 11). XMRV PLAYS A ROLE IN PROSTATE CANCER DEVELOPMENT OR PROGRESSION …. XMRV was identified in up to 23% of prostate cancer tissues and localized XMRV protein almost exclusively to neoplastic epithelial cells. This latter finding indicates that XMRV plays a role in cancer development or progression through one of the several direct mechanisms that have been well characterized for known oncogenic retroviruses. XMRV IN CHRONIC FATIGUE SYNDROME – PRELIMINARY RESULTS …. [0134] Similarly, to detect if patients with Chronic Fatigue Syndrome have evidence of XMRV infection, we collected sera from 105 patients diagnosed as having chronic fatigue syndrome and fulfilling the Fukuda criteria for diagnosis. For comparison, we also collected sera from 200 healthy volunteers. Each of these sera was used to probe a PVDF membrane onto which XMRV proteins had been transferred from a gel. …. A positive sample usually contained antibodies reactive to at least two of the following three XMRV polypeptides: SU, CA and pi 5E (see Fig. 13A). Non-reactive samples (most healthy volunteers) did not contain antibodies to SU or pl5E (Fig. 13B). ABOUT POSSIBLE SEXUAL TRANSMISSION …. [0126] Detection of XMRV sequences in ce rvical fluid It is still unknown by which route XMRV infects people. Related retroviruses spread through transfer of blood or body fluids from an infected person to a healthy person. The ability to detect XMRV in cervical fluids as described here has allows for determining a possible route of spread of virus, including spread from mother to infant during childbirth, and has important implications for public health. Furthermore, detection of XMRV in cervical fluids offers a non-invasive method to detect XMRV. MORE CONTROL RESULTS IN THE 5-10% RANGE: THE PLOT THICKENS – AND THE ICE THINS, ESPECIALLY FOR THE CONTAMINATION ADVOCATES XMRV sequences by PCR (were found) in approximately 5-10% of samples from women on whom a test to detect other viruses (such as human papilloma virus, or herpes simplex virus) had been ordered. XMRV IN SEMEN …. The ability to detect XMRV in semen is also important to determine possible routes of XMRV transmission…. XMRV DNA or RNA was found in approximately 7% of all samples tested, indicating that XMRV is present in semen obtained from otherwise healthy men who are not known to have prostate cancer or chronic fatigue syndrome, or other XMRV-associated conditions. This finding has important implications for viral spread, and tests for detection of XMRV in semen have an application in testing donor semen samples used in fertility clinics. Quote Link to comment Share on other sites More sharing options...
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