Guest guest Posted February 5, 2011 Report Share Posted February 5, 2011 Our son's IgG microbiology report came back. This was the outcome: Varicella-Zoster: immune Rubella - immune Measles - immune Mumps - POSITIVE (Patient has evidence of immunity to mumps) Diphtheria IgG Antibody: 2.087 Antibody to diphtheria present above the protective level Strep pneumoniae IgG Antibody: 536 Antibody to pneumococcus present in high titer. Tetanus Toxoid IgG Antibody: .0496 Antibody to Tetanus present above the protective level. Can someone please give me an opinion on what this means? My doctor thinks it's great that his antibodies are high. He says he is well protected. I am not as confident that high titers are such a great thing in a child with neutropenia. Any comments are very welcome. Thank you. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 5, 2011 Report Share Posted February 5, 2011 I think it means his immune system is shifted towards making antibodies, and less towards cellular immunity. In a normal person, sure, high titers means nothing more than a strong immune system. But if you do an immune panel along side that, plus have the medical history some of our kids have, and see the similarities in the findings of very high titers in CFS, then you have to see a dysfunction there. But right now, there are not normal parameters set for the percentages/ratio on the immune panel. It isn't used in most 'mainstream' the way the neuro-immune folks are looking at it. And there aren't standards even among us with . Researchers like Dr Klimas and the folks at WPI and the like are trying to identify sub-classes of the illnesses, too, because while some of the patterns of findings are very evident, it isn't universal to any of us, which is one of the reasons it's been so impossible to have an actual marker - a real lab test that we can run, take to the doctor, and that doctor be like 'Yup - that's abnormal - we have to do something about that!'. Maybe that will change soon. Dr Klimas's group just published a potential biomarker in CFS, and it has to be replicated now I guess, and more studies done, etc. WPI is doing a lot of work on the immune findings in variations of CFS too. Then we'll have to see if autism breaks down into similar subclasses as well - different aged immune systems are probably going to look different, not to mention different stages of illness. (But I think Dr Klimas's lab lined up with symptoms despite those differences...) I'm rambling tonight ... hope you find something that helps out of that. ________________________________ From: and Freeman <freemanbk@...> Sent: Sat, February 5, 2011 1:12:19 PM Subject: High titers  Our son's IgG microbiology report came back. This was the outcome: Varicella-Zoster: immune Rubella - immune Measles - immune Mumps - POSITIVE (Patient has evidence of immunity to mumps) Diphtheria IgG Antibody: 2.087 Antibody to diphtheria present above the protective level Strep pneumoniae IgG Antibody: 536 Antibody to pneumococcus present in high titer. Tetanus Toxoid IgG Antibody: .0496 Antibody to Tetanus present above the protective level. Can someone please give me an opinion on what this means? My doctor thinks it's great that his antibodies are high. He says he is well protected. I am not as confident that high titers are such a great thing in a child with neutropenia. Any comments are very welcome. Thank you. Quote Link to comment Share on other sites More sharing options...
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