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RE: Preeclampsia increases risk

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, I saw this in Wikipedia, sounds like maternal immune dysfunction, there

is also a recent study that discusses maternal immune activation is linked to

ASD : http://content.karger.com/produktedb/produkte.asp?doi=319828

 

Here is the wiki info:

The pre-eclampsia syndrome is thought in many cases to be caused by a shallowly

implanted placenta which becomes hypoxic, leading to an immune reaction

characterized by secretion of upregulated inflammatory mediators from the

placenta, and acting on the vascular endothelium. The shallow implantation is

thought to stem from the maternal immune system's response to the placenta. This

theory emphasizes the role of the maternal immune system, and refers to evidence

suggesting a lack of established immunological tolerance in pregnancy, resulting

in an immune response against paternal antigens from the fetus and its

placenta.[9] In some cases of pre-eclampsia it is thought that the mother lacks

the receptors for the proteins the placenta is using to downregulate the

maternal immune system's response to it.[10] This view is also consistent with

evidence showing many miscarriages to be an immunological disorder where the

mother's immune system " unleashes a

destructive attack on the tissues of the developing child. " [11]

In many cases of the pre-eclampsia syndrome, however, the maternal response to

the placenta appears to have allowed for normal implantation. It is possible

that women with higher baseline levels of inflammation stemming from underlying

conditions such as chronic hypertension or autoimmune disease may have less

tolerance for the inflammatory burden of pregnancy.

From: and Freeman <freemanbk@...>

Subject: Preeclampsia increases risk

Date: Tuesday, February 22, 2011, 7:13 PM

 

Can anyone explain to me why preeclampsia increases the risk of having a

child with issues? Thank you!

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,

Think of your child's health like the proverbial straws on a camels back.

Preeclampsia, or other pregnancy issues such as gestational diabetes, groups

B strep etc., a difficult or stressful birth, antibiotic use immediately

after birth for assorted issues like ingestion of meconium, assorted

infantile infections, a sickly baby with lots of ear infections, more and

more antibiotics, colds etc, etc.

Any of these can accumulatively put stress on a baby's immune system that

can affect the baby's health and therefore have issues.

That is not to say that any one or all of these issues can or will cause

, it just causes immune stress.

Then factor in diet and parents desire to feed babies (even at one year of

age) milk based products or formulas, the rush to start solid food, the

" healthy " idea that whole grains are better and so on. Young babies and kids

are fed a highly allergic diet with the best of intensions from their

parents.

Then on top of that you take family history and autoimmune or neuroimmune

diseases as common as asthma, allergies, or others like MS, diabetes, CFS

etc.

These all act accumulatively. It is very complex and there is no one cause

or reason why some kids systems react with an immune dysfunction.

Hope this helps explain it for you. Don`t hold on to any one issue as to

``why``. Spend your energy removing the immune triggers and helping your

son the best you can through diet, therapy, patience and the meds that will

help control the damage.

Lori

_____

From: [mailto: ] On Behalf Of

and Freeman

Sent: February-22-11 8:13 PM

Subject: Preeclampsia increases risk

Can anyone explain to me why preeclampsia increases the risk of having a

child with issues? Thank you!

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