Amantadine

[Guest guest]

Hi Katrina,

I took Amantadine for 2 months about 15 years ago. The

first few days felt like I was on speed. I didn't

sleep and my mind buzzed constantly.

After a few days of the speedy effect I crashed badly

and the rest of the time on Amantadine I didn't notice

any other effects.

Sorry I don't remember the dose. My doc and I tried

smaller and larger doses but no return to the buzzing

and no change to my ME symptoms.

Kindest regards,

Annette

__________________________________________________

[Guest guest]

Isn't this a flu drug?????

" All the truth in the world adds up to one big lie. "

~ Bob Dylan ~

[Guest guest]

Isn't this a flu drug?????

" All the truth in the world adds up to one big lie. "

~ Bob Dylan ~

[Guest guest]

Could you be thinking of Augmentin?

glitterari@... wrote:

Isn't this a flu drug?????

" All the truth in the world adds up to one big lie. "

~ Bob Dylan ~

[Guest guest]

Could you be thinking of Augmentin?

glitterari@... wrote:

Isn't this a flu drug?????

" All the truth in the world adds up to one big lie. "

~ Bob Dylan ~

[Guest guest]

It has some Asian flu uses from my readings but it's an antiparkinsons type

drug. Anti-seizure type drug like Depakote which the psychs love to use.

Jim

Isn't this a flu drug?????

" All the truth in the world adds up to one big lie. "

~ Bob Dylan ~

[Guest guest]

I have not heard of Amantadine. - Dom

>

> Just wondering if anyone has had any experience with Amantadine. My

> doctor put me on it for fatigue. It seems to be helping some.

[Guest guest]

HI ALL,RECENTLY A TRIAL IN DOUBLE BLIND DONE BY THE ITALIAN UNIVERSITY LA

SAPIENZA IN ROME,WITH MANTADAN(AMANTADINE )AND ALC(ACETIL LEVO CARNITINE)TO

VERIFY WHICH OF THE TWO MEDS WAS MORE EFFECTIVE IN REDUCING MS TIREDNESS AND

FATIGUE,SHOWED THAT ALC IS BETTER THAN AMANTADINE.

HERE IS THE REPORT

http://www.la-sclerosimultipla.net/acetilcarnitina.php

MY BAST

low dose naltrexone , " Joan Cowdrick " <cowsarus@...> wrote:

>

> Sally,

> I take amantadine for fatigue. Since I have high blood pressure, I

cannot take Provigial. There are no side effects but I only take 1 pill in the

morning. Does it help? Not sure, did not notice a difference in my fatigue

until I started LDN.

> Joan, PA

> Col. Potter's Cairn Rescue

> Cookbook is ready to Pre-order

> Please click below

> http://mall.cairnrescue.com/inv_cookbook.htm#order

>

[Guest guest]

I have heard in the group that Dr Goldberg does not prescribe Amantadine but

some of his patients have used/using it.

What does it help with - seems like it can work as an anti-viral for RNA viruses

and also has some Dopamine enhancing effects.

Curious as to what people's experience with it and what Dr Goldberg thinks about

it?

Kay

[Guest guest]

I haven't used amantadine on my son but I found this study on the NIH web site:

Double-blind, placebo-controlled study of amantadine hydrochloride in the

treatment of children with autistic disorder.

King BH, DM, Handen BL, Sikich L, Zimmerman AW, McMahon W, Cantwell E,

Davanzo PA, Dourish CT, Dykens EM, Hooper SR, Jaselskis CA, Leventhal BL, Levitt

J, Lord C, Lubetsky MJ, Myers SM, Ozonoff S, Shah BG, Snape M, Shernoff EW,

on K, Cook EH Jr.

Department of Psychiatry, Dartmouth Medical School, Hanover, NH 03756-0001, USA.

.H.King@...

Abstract

OBJECTIVE: To test the hypothesis that amantadine hydrochloride is a safe and

effective treatment for behavioral disturbances--for example, hyperactivity and

irritability--in children with autism.

 

METHOD: Thirty-nine subjects (intent to treat; 5-19 years old; IQ > 35) had

autism diagnosed according to DSM-IV and ICD-10 criteria using the Autism

Diagnostic Interview-Revised and the Autism Diagnostic Observation

Schedule-Generic. The Aberrant Behavior Checklist-Community Version (ABC-CV) and

Clinical Global Impressions (CGI) scale were used as outcome variables. After a

1-week, single-blind placebo run-in, patients received a single daily dose of

amantadine (2.5 mg/kg per day) or placebo for the next week, and then bid dosing

(5.0 mg/kg per day) for the subsequent 3 weeks.

 

RESULTS: When assessed on the basis of parent-rated ABC-CV ratings of

irritability and hyperactivity, the mean placebo response rate was 37% versus

amantadine at 47% (not significant). However, in the amantadine-treated group

there were statistically significant improvements in absolute changes in

clinician-rated ABC-CVs for hyperactivity (amantadine -6.4 versus placebo -2.1;

p = .046) and inappropriate speech (-1.9 versus 0.4; p = .008). CGI scale

ratings were higher in the amantadine group: 53% improved versus 25% (p = .076).

Amantadine was well tolerated.

 

CONCLUSIONS: Parents did not report statistically significant behavioral change

with amantadine. However, clinician-rated improvements in behavioral ratings

following treatment with amantadine suggest that further studies with this or

other drugs acting on the glutamatergic system are warranted. The design of

these and similar drug trials in children with autistic disorder must take into

account the possibility of a large placebo response.

http://www.ncbi.nlm.nih.gov/pubmed/11392343

 

From: Kay <kp_mlist@...>

Subject: Amantadine

Date: Wednesday, April 6, 2011, 2:37 PM

 

I have heard in the group that Dr Goldberg does not prescribe Amantadine but

some of his patients have used/using it.

What does it help with - seems like it can work as an anti-viral for RNA viruses

and also has some Dopamine enhancing effects.

Curious as to what people's experience with it and what Dr Goldberg thinks about

it?

Kay

[Guest guest]

Often these short term studies show minor improvement.......the question is what

if the study was done for longer and at a higher dose? Would the results be

better?

 

From: Kay <kp_mlist@...>

Subject: Amantadine

Date: Wednesday, April 6, 2011, 2:37 PM

 

I have heard in the group that Dr Goldberg does not prescribe Amantadine but

some of his patients have used/using it.

What does it help with - seems like it can work as an anti-viral for RNA viruses

and also has some Dopamine enhancing effects.

Curious as to what people's experience with it and what Dr Goldberg thinks about

it?

Kay

[Guest guest]

Thanks . This was 10 years ago - surprised it has not been studied more.

Looks like there are some studies that claim it is effective as an antiviral

against the Rubella/Measles type viruses.

Wondering if anyone has had any experience - also from any adults who have

taken it.

Thanks,

Kay

________________________________

From: Aronson <sailcharters@...>

Sent: Wed, April 6, 2011 12:13:08 PM

Subject: Re: Amantadine

I haven't used amantadine on my son but I found this study on the NIH web site:

Double-blind, placebo-controlled study of amantadine hydrochloride in the

treatment of children with autistic disorder.

King BH, DM, Handen BL, Sikich L, Zimmerman AW, McMahon W, Cantwell E,

Davanzo PA, Dourish CT, Dykens EM, Hooper SR, Jaselskis CA, Leventhal BL, Levitt

J, Lord C, Lubetsky MJ, Myers SM, Ozonoff S, Shah BG, Snape M, Shernoff EW,

on K, Cook EH Jr.

Department of Psychiatry, Dartmouth Medical School, Hanover, NH 03756-0001, USA.

.H.King@...

Abstract

OBJECTIVE: To test the hypothesis that amantadine hydrochloride is a safe and

effective treatment for behavioral disturbances--for example, hyperactivity and

irritability--in children with autism.

METHOD: Thirty-nine subjects (intent to treat; 5-19 years old; IQ > 35) had

autism diagnosed according to DSM-IV and ICD-10 criteria using the Autism

Diagnostic Interview-Revised and the Autism Diagnostic Observation

Schedule-Generic. The Aberrant Behavior Checklist-Community Version (ABC-CV) and

Clinical Global Impressions (CGI) scale were used as outcome variables. After a

1-week, single-blind placebo run-in, patients received a single daily dose of

amantadine (2.5 mg/kg per day) or placebo for the next week, and then bid dosing

(5.0 mg/kg per day) for the subsequent 3 weeks.

RESULTS: When assessed on the basis of parent-rated ABC-CV ratings of

irritability and hyperactivity, the mean placebo response rate was 37% versus

amantadine at 47% (not significant). However, in the amantadine-treated group

there were statistically significant improvements in absolute changes in

clinician-rated ABC-CVs for hyperactivity (amantadine -6.4 versus placebo -2.1;

p = .046) and inappropriate speech (-1.9 versus 0.4; p = .008). CGI scale

ratings were higher in the amantadine group: 53% improved versus 25% (p = .076).

Amantadine was well tolerated.

CONCLUSIONS: Parents did not report statistically significant behavioral change

with amantadine. However, clinician-rated improvements in behavioral ratings

following treatment with amantadine suggest that further studies with this or

other drugs acting on the glutamatergic system are warranted. The design of

these and similar drug trials in children with autistic disorder must take into

account the possibility of a large placebo response.

http://www.ncbi.nlm.nih.gov/pubmed/11392343

From: Kay <kp_mlist@...>

Subject: Amantadine

Date: Wednesday, April 6, 2011, 2:37 PM

I have heard in the group that Dr Goldberg does not prescribe Amantadine but

some of his patients have used/using it.

What does it help with - seems like it can work as an anti-viral for RNA viruses

and also has some Dopamine enhancing effects.

Curious as to what people's experience with it and what Dr Goldberg thinks about

it?

Kay