Guest guest Posted July 14, 2011 Report Share Posted July 14, 2011 All of the same problems with OH (orthostatic hypotension) and incontinence can occur in LBD. Dementia is an exclusionary criteria for MSA. In any case, it sounds as if your mother is being well treated for her LBD symptoms. I've helped well over 100 families accomplish brain donation, and I've read many of their neuropathology reports. If the donor is older, there are typically several pathologies in the brain. > > Mom's diagnosis at this point is officially MSA, four years ago it was Parkinson's and then lack of response to sinemet and rapidly progressing confusion changed it to LBD (and one horrific hallucination) and then the blood pressure and incontinence issues changing it to MSA. She may have a very unique form of neurologic degeneration with aspects of each. The tremors that were once so bad are now almost non-existent and she is on a trace dose of Sinemet (1/2 of 25/100 twice a day), Aricept and Namenda and Celexa for her mental issues. She was on Mitodrine but her blood pressure was going so high when she lay down and she felt much worse on the medication so it was discontinued. Same for Flouronef (sp?). These days she is very content and seemingly happy, but speech aphasia has robbed her of communication most of the time that but se still recognizes those she cares for, and can speak about an amazing array of topic with clarity at certain > times. Most of her hallucinations are upon waking. She's almost completely confined to a wheelchair and has a prominent " Pisa effect " to the right, which some doctors have pointed out at she is peaceful and not in any pain. > > > Quote Link to comment Share on other sites More sharing options...
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