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The Hoffman sign is when one flicks the nail on a person with " upper

motor

neuron disease " there is a flexure or inward movement of one's

thumb.I do not

know who Hoffman was, but I suspect he was a neurologist. The sign

means thre

same as the " Babinski " means in the lower extremity, that this

indicates

" upper motor neuron disaease " or a lack of reflex motor control.If

one has

lower moton neuron disease this reflex will be lost.These abnormal

signs

require an intact lower neuron system. I do know that Babinski was a

neurologist.It is quite characteristic of a person with PLS and it

does occur

early in ALS before there is lower motor damage. You can't elicit

these

findings or yourself, just as you cannot tickel yourself. Dr. Bill

--- End forwarded message ---

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