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Re: Human Growth Hormone..... Val

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I am really nto sure about the test which one are they doing? the one I

read th most about is the Arginine stimulation test,. if they plan on

just a lod draw to check GH levels it will NOT work. GH is released in

spurts mostly at night, and is gone ina matter of minutes. The

firstscreening fo rit si an IGF-1 which is a metabolite of it. If it si

OK your GH must be fairly good. Mine OGF-1 was undetectable, but even

after 5 motnhs of GH injectiosn it was still undetectable, so I ahve

stopped GH as it si not helping me. now I find out there is injectible

IGF-1 but it is abtou 5 times more $$$ than GH and no way I can afford it.

--

Artistic Grooming- Hurricane WV

http://www.stopthethyroidmadness.com/

http://health.groups.yahoo.com/group/NaturalThyroidHormonesADRENALS/

http://health.groups.yahoo.com/group/RT3_T3/

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You know Val, from hypopit, says that the IGF-1 does not really

indicate what your growth hormone is doing. Your IGF-1 could be high

and hgh be low and vice-versa. Do you have an opinion on that ? How

do you prepare for the Arginine test? Do I have to be off HC ? -If so

Oh Boy....Also does HGH have anything to do with bone loss? Okay Val,

hope you had a nice Thanksgiving. Take care, lots of appreciation...

Thanks,

-- In RT3_T3 ,

wrote:

>

> I am really nto sure abouthe test which one are they doing? the one

I

> read th most about is the Arginine stimulation test,. if they plan

on

> just a lod draw to check GH levels it will NOT work. GH is released

in

> spurts mostly at night, and is gone ina matter of minutes. The

> firstscreening fo rit si an IGF-1 which is a metabolite of it. If

it si

> OK your GH must be fairly good. Mine OGF-1 was undetectable, but

even

> after 5 motnhs of GH injectiosn it was still undetectable, so I

ahve

> stopped GH as it si not helping me. now I find out there is

injectible

> IGF-1 but it is abtou 5 times more $$$ than GH and no way I can

afford it.

>

> --

> Artistic Grooming- Hurricane WV

>

> http://www.stopthethyroidmadness.com/

>

http://health.groups.yahoo.com/group/NaturalThyroidHormonesADRENALS/

> http://health.groups.yahoo.com/group/RT3_T3/

>

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Before IGF-1 is even tested thyroid and cortisl need to be adjusted

RIGHT. Eithe one being too low can cause GH to not convert to IGF-1,

but as it is a normal metabolite of GH I would say once cortil and

thyroid are corrected if oyu have low IGF-1 you almost are guaranteed to

have low GH. I recently talked to a company rep that is making synthetic

IGF-1 nan he says he has never heard of ANYONE aduklt woth NOIGF-1, soI

am indeed a rare case. Usually evenpeople with very low GH will have

some IGF-1. That is the only test my doctor does for GH before he

prescribes it an he is very good with homrones, but he also does nto do

the test until the cortils and thyroid are properly supported.

--

Artistic Grooming- Hurricane WV

http://www.stopthethyroidmadness.com/

http://health.groups.yahoo.com/group/NaturalThyroidHormonesADRENALS/

http://health.groups.yahoo.com/group/RT3_T3/

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OOPS, I am not sure about actual bone loss but GH does strengthen bones

so it may counter the bone loss of aging that we all suffer to some

degree. I do nto knwo what is needed to be don for arginine stim

testing, probabyl just fasting.

--

Artistic Grooming- Hurricane WV

http://www.stopthethyroidmadness.com/

http://health.groups.yahoo.com/group/NaturalThyroidHormonesADRENALS/

http://health.groups.yahoo.com/group/RT3_T3/

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I've actually done a bit of research on this, forgive me for not

having the documents to hand, but what can be generally argued is

that a low IGF-1 correlates with low HGH, a high end of normal IGF-1

correlates with normal GH, but mid range IGF-1 can correlate with

very low GH also, this is due to spikes in IGF-1 production, must be

tested fasting and even then, within the normal range it doesn't tell

you anything except what your IGF-1 was, not diagnostically accurate

for HGH.

I am about to do a 24 hour urine HGH test (actually have completed

the collection) and it is to be tested for HGHbH, I didn't know there

was a binding globulin for HGH, but I guess there is for everything

else right? :-) Arginine Stim and ITT are considered diagnostically

accurate, only methods that i know that are, and ITT can be dangerous

for lots of people...

Plus when measuring IGF-1, IGF-1 binding proteins must be counted or

it's useless! will show much higher than it really is as it's

pooling... called IGFBps, mainly IGFbp3

plus did you know commercially farmed cows milk drinkers can have

artificially high IGF-1 levels from the Rgbh injected into cows?

I have more articles squirreled away but here's a quick one:

http://pituitary.mgh.harvard.edu/NCBV11I1.htm

Cat

>

> Before IGF-1 is even tested thyroid and cortisl need to be

adjusted

> RIGHT. Eithe one being too low can cause GH to not convert to IGF-

1,

> but as it is a normal metabolite of GH I would say once cortil and

> thyroid are corrected if oyu have low IGF-1 you almost are

guaranteed to

> have low GH. I recently talked to a company rep that is making

synthetic

> IGF-1 nan he says he has never heard of ANYONE aduklt woth NOIGF-1,

soI

> am indeed a rare case. Usually evenpeople with very low GH will

have

> some IGF-1. That is the only test my doctor does for GH before he

> prescribes it an he is very good with homrones, but he also does

nto do

> the test until the cortils and thyroid are properly supported.

>

> --

> Artistic Grooming- Hurricane WV

>

> http://www.stopthethyroidmadness.com/

>

http://health.groups.yahoo.com/group/NaturalThyroidHormonesADRENALS/

> http://health.groups.yahoo.com/group/RT3_T3/

>

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PS - that's HGHbG not bH, and I'm being tested for IGF-1 + IGFbg's as

well so should have some comparison... could be interesting!

> >

> > Before IGF-1 is even tested thyroid and cortisl need to be

> adjusted

> > RIGHT. Eithe one being too low can cause GH to not convert to IGF-

> 1,

> > but as it is a normal metabolite of GH I would say once cortil

and

> > thyroid are corrected if oyu have low IGF-1 you almost are

> guaranteed to

> > have low GH. I recently talked to a company rep that is making

> synthetic

> > IGF-1 nan he says he has never heard of ANYONE aduklt woth NOIGF-

1,

> soI

> > am indeed a rare case. Usually evenpeople with very low GH will

> have

> > some IGF-1. That is the only test my doctor does for GH before he

> > prescribes it an he is very good with homrones, but he also does

> nto do

> > the test until the cortils and thyroid are properly supported.

> >

> > --

> > Artistic Grooming- Hurricane

WV

> >

> > http://www.stopthethyroidmadness.com/

> >

> http://health.groups.yahoo.com/group/NaturalThyroidHormonesADRENALS/

> > http://health.groups.yahoo.com/group/RT3_T3/

> >

>

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I would love to see mroe IGF-1 testing as I am feeling rather alone in

this deficiency! LOL My doctor says he has NEVER seen any one wht

undetectable IGF-1 til me. Even folks with VERY lwo GH or even none ona

stim test have SOME IGF-1 he says usually 50-100 my lab went to 23 and

the result was <23...

--

Artistic Grooming- Hurricane WV

http://www.stopthethyroidmadness.com/

http://health.groups.yahoo.com/group/NaturalThyroidHormonesADRENALS/

http://health.groups.yahoo.com/group/RT3_T3/

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:-)

you're never alone Val!!! but in my limited experience, I've never

heard of zero IGF-1 either... :-O eek!~!!

fwiw, my previous serum igf-1 was just in the normal range and i had

turned 40 a couple of months prior (i am now about to turn 42) - it

was a new assay so hard to equate it with historical tests. :-(

oh well, $1,000AUD worth of tests today (that's about 33C US today -

LOL) and several hundred to express courier the lot half way across

the country as urgent - that'll teach me to do better research on lab

stuff first!!!

>

> I would love to see mroe IGF-1 testing as I am feeling rather alone

in

> this deficiency! LOL My doctor says he has NEVER seen any one wht

> undetectable IGF-1 til me. Even folks with VERY lwo GH or even none

ona

> stim test have SOME IGF-1 he says usually 50-100 my lab went to 23

and

> the result was <23...

>

> --

> Artistic Grooming- Hurricane WV

>

> http://www.stopthethyroidmadness.com/

>

http://health.groups.yahoo.com/group/NaturalThyroidHormonesADRENALS/

> http://health.groups.yahoo.com/group/RT3_T3/

>

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