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Human stem cell cloned

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This morning on the Today show there was a news report

about the announcement from a California lab that it

had successfully cloned a human stem cell. Two

medical experts interviewed, based on the information

they had, thought the report was creditable, unlike

the bogus one from Korea.

My question is: Could it have ramifications for

metastatic prostate cancer, down the line?

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>

> This morning on the Today show there was a news report

> about the announcement from a California lab that it

> had successfully cloned a human stem cell. ...

>

> My question is: Could it have ramifications for

> metastatic prostate cancer, down the line?

Speaking from my lofty position of ignorance, I can answer with

completely unwarranted assurance - yes, this will have

ramifications down the line, but no, not in the short term

future.

Why will it have ramifications? Because all basic biological

research has ramifications for medicine.

Why not in the short term future? Because stem cell research is

still in very early stages. It will take many years, probably

decades, for practical medical therapies to become available.

Stem cells, especially fetal stem cells, are relatively

" undifferentiated " cells. That means that they are generic cells

that have not yet acquired the specialized characteristics of

bone cells, muscle cells, nerve cells, skin cells, prostate

cells, etc. They are important because they can divide and

reproduce themselves, and they can grow into different kinds of

cells depending on what chemical signals they receive from their

surroundings in the body.

Many other types of cells cannot divide and reproduce, nor can

they transform themselves into some other kind of cell. A muscle

cell cannot become a brain cell or vice versa, but a stem cell

can become either one. If a brain cell is destroyed, it's

neighboring cells cannot just divide and reproduce to replace it.

But a stem cell can.

I would think that stem cells would be of most immediate interest

for repairing damage in areas where new cells are not growing.

Examples include brain and nerve injuries, Parkinson's,

Alzheimer's, heart disease, wounds, damage to various kinds of

organs, etc. I don't know what their applicability is to cancer

- which is not caused by the death of cells that need to be

replaced, but by the opposite problem, cells that reproduce and

spread over the body when they should not.

So why do I say that there will be long term ramifications?

I think that if cancer is ever overcome it will be because we

have a much, much deeper understanding of the whole disease

process, all the way down to how individual molecules react

inside the cell. This may or may not lead to actually using stem

cells in cancer treatment, but I'm sure it will help us to

understand the basic molecular biology involved in all cell

processes, including the development of cancer.

Alan Meyer

ameyer2@...

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Norman Maitland has been isolating and growing PCA stem cells for some time in the University of York, Yorkshire England

B

Re:Human stem cell cloned

>> This morning on the Today show there was a news report> about the announcement from a California lab that it> had successfully cloned a human stem cell. ...>

..

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