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Re: Can the PSA go down?

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My PSA has gone down.

Age-46

Stage T1c

Gleason 6 (3+3)

No Bone Scan or CAT Scan

Scheduled for surgery Jan 10, 2008 (one week away)

Diagnosed through Biopsy 6/21/07 (2 cores out of 20 positive)

Follow-up biopsy 10/07(2 cores out of 14 positive, more cancer than

1st biopsy)

Date PSA

07/01/06 3.40

05/24/07 3.13

09/10/07 2.77

10/02/07 3.68 <---A slight peak

12/15/07 2.37

Ignoring 10/02, there is a steady (non-linear, more of a 2nd order

polynomial curve) decline.

But does it MEAN anything?!?!

--Steve

>

> I was diagnosed with Pca in August,2007.

>

> My numbers are:

>

> Age-60

> PSA 3.17 (Had doubled in 18 months)

> Stage T1c

> Gleason 6 (3+3)

> Bone Scan & CAT Scan-Negative

> Active Surveillance

>

> I will be getting another PSA next week. Can the PSA go down? If

so, why?

>

> Thanks,

>

> Sy

>

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Steve, It may be due to some sort of dietary change that you

knowingly of unknowingly made, or it may just be a " seasonal "

variation (I have read od such).

Regardless, with your stats, there is no huge rush to treatment--

Have you thoroughly investigated all your options, or are you going

on the one urolologist (surgeon's) recommendation? Just a caution to

make sure that you have made a choice that is yours and yours alone,

based on your best info and studies.

Fuller

Fuller

> >

> > I was diagnosed with Pca in August,2007.

> >

> > My numbers are:

> >

> > Age-60

> > PSA 3.17 (Had doubled in 18 months)

> > Stage T1c

> > Gleason 6 (3+3)

> > Bone Scan & CAT Scan-Negative

> > Active Surveillance

> >

> > I will be getting another PSA next week. Can the PSA go down? If

> so, why?

> >

> > Thanks,

> >

> > Sy

> >

>

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Fuller,

I tried Watchful Waiting, under the European/American eye of Dr.

Bertrand Guillonneau at Memorial Sloan kettering. He said I had too

much " volume " of cancer in my most recent biopsy. Positive for 2

out of 14 samples, but still Stage T1c and Gleason 3+3.

I also spoke with Dr. G...for about 2 hours!...in Manhattan, and he

and I went over many options. he does not perform PCa surgery, so

he (theoretically) was not biased towards it. He did have manual

lararoscopic surgery performed on HIMSELF about a year ago, by

Guillonneau (but only aftert Guillonneau recommended to him that he

consider Watchful Waiting). And my original diagnosing Uro

recommended surgery, with Scheuch or Tewari.

Plus my own, educated, engineering opinion also supports surgery as

an option. WW was my first thought, but my expert on that

(Guillonneau) put the kibosh on it.

At this point, I've waited over half a year. For insurance reasons,

as well as other practical reasons, I can't/shouldn't wait any

longer.

--Steve

>

> Steve, It may be due to some sort of dietary change that you

> knowingly of unknowingly made, or it may just be a " seasonal "

> variation (I have read od such).

>

> Regardless, with your stats, there is no huge rush to treatment--

> Have you thoroughly investigated all your options, or are you

going

> on the one urolologist (surgeon's) recommendation? Just a caution

to

> make sure that you have made a choice that is yours and yours

alone,

> based on your best info and studies.

>

> Fuller

>

> Fuller

>

>

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