Mitochondrial Disease in Autism Spectrum Disorder Patients: A Cohort Analysis

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Mitochondrial Disease in Autism Spectrum Disorder Patients: A Cohort

Analysis

http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0003815

Conclusions/Significance: Although all patients' initial diagnosis was

idiopathic autism, careful clinical and biochemical assessment

identified clinical findings that differentiated them from children with

idiopathic autism. These and prior data suggest a disturbance of

mitochondrial energy production as an underlying pathophysiological

mechanism in a subset of individuals with autism.

*Citation: *Weissman JR, Kelley RI, Bauman ML, Cohen BH, Murray KF, et

al. (2008) Mitochondrial Disease in Autism Spectrum Disorder Patients: A

Cohort Analysis. PLoS ONE 3(11): e3815. doi:10.1371/journal.pone.0003815