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Genetic Testing

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Regarding 's question about odds, I assume she's asking the odds that

she and her husband are carriers of mutant genes. The data she gives do not

allow assessment of spontaneous mutations and environmental factors.

If she or her husband had a dominant mutation, I would expect the carrier

to have some sort of hearing abnormality, so I think those possiblities are

unlikely. Anyone who wants to challenge because of possible variable

expressivity or genetic anticipation can feel free to work the odds.

If she and her husband each had a recessive mutation, the odds of one out

of two children being deaf are 3/8.

A different viewpoint on genetic testing and insurance: People on this list

seem to be concerned about whether insurance will pay for testing. On some

other disability-related lists I've participated in, the concerns are

different. People are concerned that once they're determined to be carrying

a mutant gene with increased risk of problems, that could be considered a

" preexisting condition " and the insurance carriers would refuse to cover

it.

Leon

Leon Metlay and Nina Klionsky metlionsky@...

Making the world safe for dustbunnies since 1977

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