Re: Prednisolone side effects? AH!!!!!!!!

[Guest guest]

When my son was on prednisone before his transplant, it was always an every

other day dose (starting at 80 mg.), and yes ­ he had major side effects.

Acne, ravenous appetite, weight gain, mood swings, lethargy, etc. etc. I¹d

hate to see what it would have been like on an every day dose. Since the

transplant, he has been on every day dosage but tapered down fairly quickly.

Still similar side effects early on but not as severe ­ except for being

occasionally hostile and short-tempered when the dose was still fairly high.

So ­ no ­ I don¹t think you¹re imagining it.

Betsy

On 12/16/02 6:07 AM, " Nick_Batchelor "

wrote:

> Has anyone experienced side effects from Prednisolone when they are

> taking an alternate day dose? Eg, 50mg every other day seems common.

>

> I think it's making me short tempered, but maybe I'm imagining it on

> this dose?

>

> Think I'll go yell at someone

>

>

>

> To edit your settings for the group, go to our Yahoo Group

> home page:

> http://groups.yahoo.com/group/iga-nephropathy/

> Visit our companion website at www.igan.ca

>

>

[Guest guest]

Yes. Weight loss and acne.

Proteninuria lowered from 300 mg/dl to 30 mg/dl and then has stopped

to lower (creatinine from 1.7 to 1.5).

I begun 6 moth ago with 25 mg/day of prednisolone (+Ramipril, an ACE-

inhibitor), and now I take 20 mg / day. Probably I continue for the

next months lowering 2,5 mg / month, because Prednisolone seem to

have no more effects on my IGA, diagnosed only 7 months ago (I am 42

years old). Perhaps my nephrologist will prescribe me Cellcept, but I

am not sure.

Silvano

> Has anyone experienced side effects from Prednisolone when they are

> taking an alternate day dose? Eg, 50mg every other day seems

common.

>

> I think it's making me short tempered, but maybe I'm imagining it

on

> this dose?

>

> Think I'll go yell at someone

[Guest guest]

Yes prednisone can make you very moody,one day you can be the worst S.O.B

and the next day you can be sweet as a pie.

Go read the book by Eugenia Zukerman/ R Ingelfinger

Book is called : Coping with Prednisone.A very informative read.

[Guest guest]

Hi Nick

I'm on a 80mg every day dose of prednisolone, and can quite relate

to your side effects...2 days of feeling top of the world followed

by a few nights of no sleep and feeling very, very down for no(!)

reason. Oh, and the eating enough for three people at each meal,

acne, muscle loss to fast you can see it and that all so lovely

round face effect we all know and love!

And to top it all, I keep engaging my mouth before my brain when

with people, and what I intend as a light hearted remark comes out

as a terribly short insult! Luckily for me this happens mainly at my

rugby club, so they just say something worse and laugh about it..the

joys of being in a thick skinned community!

I think most of those side effects were mentioned at some point, as

I certainly don't get like that when not on them. Hopefully I'll be

able to taper down soon when the proteinuria gets under control.

Why not persuade someone to get you a rubber stress ball for xmas,

might sort you out a treat!

take it easy,

Cambridge, UK

> Has anyone experienced side effects from Prednisolone when they

are

> taking an alternate day dose? Eg, 50mg every other day seems

common.

>

> I think it's making me short tempered, but maybe I'm imagining it

on

> this dose?

>

> Think I'll go yell at someone

[Guest guest]

I wish it was that easy! My husband is telling me I look anorexic lately! I

have been trying to pump up the caloric intake recently.

I guess it is frustrating on both ends of the weight issue isn't it!

I hated being on prednisone so much because I got so emotional. I cried

during commercials on TV!!! I don't ever want to go on it again if I can

help it.

Sorry you have to endure it.

[Guest guest]

A relative of mine has been on prednisone for maybe six months (not related

to kidney disease at all). She didn't like not being able to put her normal

slacks on because of the weight gain, but when her hair started falling out,

that was enough for her. Under her doctor's instructions, she is now

tapering off the prednisone.

Pierre

Re: Prednisolone side effects? AH!!!!!!!!

When my son was on prednisone before his transplant, it was always an every

other day dose (starting at 80 mg.), and yes ­ he had major side effects.

Acne, ravenous appetite, weight gain, mood swings, lethargy, etc. etc. I¹d

hate to see what it would have been like on an every day dose. Since the

transplant, he has been on every day dosage but tapered down fairly quickly.

Still similar side effects early on but not as severe ­ except for being

occasionally hostile and short-tempered when the dose was still fairly high.

So ­ no ­ I don¹t think you¹re imagining it.

Betsy

On 12/16/02 6:07 AM, " Nick_Batchelor "

wrote:

> Has anyone experienced side effects from Prednisolone when they are

> taking an alternate day dose? Eg, 50mg every other day seems common.

>

> I think it's making me short tempered, but maybe I'm imagining it on

> this dose?

>

> Think I'll go yell at someone

>

>

>

> To edit your settings for the group, go to our Yahoo Group

> home page:

> http://groups.yahoo.com/group/iga-nephropathy/

> Visit our companion website at www.igan.ca

>

>

[Guest guest]

I would expect prednisone to have an effect on heavy proteinuria, but I

wouldn't expect measurable effects on creatinine. It can happen, but it's

just not something that will usually cause any dramatic improvement in terms

of the chronic renal failure in adult IgAN patients. A drop in serum cr from

1.7 to 1.5 is pretty meaningless - but of course, it's better than an

increase. Good luck with the Cellcept if you do end up taking it.

Pierre

Re: Prednisolone side effects? AH!!!!!!!!

> Yes. Weight loss and acne.

>

> Proteninuria lowered from 300 mg/dl to 30 mg/dl and then has stopped

> to lower (creatinine from 1.7 to 1.5).

> I begun 6 moth ago with 25 mg/day of prednisolone (+Ramipril, an ACE-

> inhibitor), and now I take 20 mg / day. Probably I continue for the

> next months lowering 2,5 mg / month, because Prednisolone seem to

> have no more effects on my IGA, diagnosed only 7 months ago (I am 42

> years old). Perhaps my nephrologist will prescribe me Cellcept, but I

> am not sure.

>

> Silvano

>

[Guest guest]

Gee, the weight gain - don't even talk to me about

that at the moment!! I reckon I'm probably going to

put on a stack of weight with the stupid prednisolone,

and I don't need that, I'm telling you. - you

said you have trouble keeping the weight on - you

don't want some of mine, do you?? LOL

--- " Pierre L (groups) "

wrote: > A relative of mine has been on prednisone for

maybe

> six months (not related

> to kidney disease at all). She didn't like not being

> able to put her normal

> slacks on because of the weight gain, but when her

> hair started falling out,

> that was enough for her. Under her doctor's

> instructions, she is now

> tapering off the prednisone.

>

> Pierre

>

>

> Re: Prednisolone side effects?

> AH!!!!!!!!

>

>

> When my son was on prednisone before his transplant,

> it was always an every

> other day dose (starting at 80 mg.), and yes ­ he

> had major side effects.

> Acne, ravenous appetite, weight gain, mood swings,

> lethargy, etc. etc. I¹d

> hate to see what it would have been like on an every

> day dose. Since the

> transplant, he has been on every day dosage but

> tapered down fairly quickly.

> Still similar side effects early on but not as

> severe ­ except for being

> occasionally hostile and short-tempered when the

> dose was still fairly high.

> So ­ no ­ I don¹t think you¹re imagining it.

>

> Betsy

>

> On 12/16/02 6:07 AM, " Nick_Batchelor

> "

> wrote:

>

> > Has anyone experienced side effects from

> Prednisolone when they are

> > taking an alternate day dose? Eg, 50mg every

> other day seems common.

> >

> > I think it's making me short tempered, but maybe

> I'm imagining it on

> > this dose?

> >

> > Think I'll go yell at someone

> >

> >

> >

> > To edit your settings for the group, go to our

> Yahoo Group

> > home page:

> > http://groups.yahoo.com/group/iga-nephropathy/

> > Visit our companion website at www.igan.ca

> >

> >

[Guest guest]

Probably (but I am not a doctor) the creatinine is lower than 6

months ago, also if I am conscious it is not a relevant thing, also

for a small change in diet (I no more drink milk for example - I

drink tea instead, that I never drink before).

An error (pardon, but my original language is Italian): not weigth

loss but weight gain (the normal side-effect of prednisone)

Silvano

> I would expect prednisone to have an effect on heavy proteinuria,

but I

> wouldn't expect measurable effects on creatinine. It can happen,

but it's

> just not something that will usually cause any dramatic improvement

in terms

> of the chronic renal failure in adult IgAN patients. A drop in

serum cr from

> 1.7 to 1.5 is pretty meaningless - but of course, it's better than

an

> increase. Good luck with the Cellcept if you do end up taking it.

>

> Pierre

>

>

> Re: Prednisolone side effects? AH!!!!!!!!

>

>

> > Yes. Weight loss and acne.

> >

> > Proteninuria lowered from 300 mg/dl to 30 mg/dl and then has

stopped

> > to lower (creatinine from 1.7 to 1.5).

> > I begun 6 moth ago with 25 mg/day of prednisolone (+Ramipril, an

ACE-

> > inhibitor), and now I take 20 mg / day. Probably I continue for

the

> > next months lowering 2,5 mg / month, because Prednisolone seem to

> > have no more effects on my IGA, diagnosed only 7 months ago (I am

42

> > years old). Perhaps my nephrologist will prescribe me Cellcept,

but I

> > am not sure.

> >

> > Silvano

> >

[Guest guest]

Hi CC

My Creatinine Clearance is in the low 30's which puts me right on the edge of

stage 3, just a point away from stage 4. I think it is fairly normal as you

lost kidney function to begin to have less of an appetite, and therefore more

of a tendency to lose weight. For me, it is also the dietary restrictions

since many of my favorite fruits and veggies are off limits due to potassium

restrictions, and low protein diet.

Interestingly enough, on my last visit to my neph, he said I have reached the

point of really no return, and that continuing to be so strict with my

protein intake is no longer necessary. Not that I can go out and eat a huge

steak, but just that I don't have to be as restrictive. I think he is more

concerned about caloric intake.

On reduced urinalysis, I know that is true for me. I go much less often,

sometimes as long as 10+ hours in between voids. But, as Pierre can tell

you, even after you start dialysis, you still can continue to void, and the

bonus is that you can increase your fluid intake by the amount you void over

and above your allotment.

Have a great day today CC.

[Guest guest]

,

I was emotional myself. I wouldn't say that I cried during commercials but

I will say that I think my wife for the first time in years wanted me to be

somewhere other than at home. I think I drove her absolutely crazy although

she has never admitted that to me. I hope I never have to use Prednisone

AGAIN! I have been off of it for 5 months now and I have gained a total of

20 pounds. My only hope is that I can lose the weight.

(Oklahoma)

Re: Prednisolone side effects? AH!!!!!!!!

I wish it was that easy! My husband is telling me I look anorexic lately!

I

have been trying to pump up the caloric intake recently.

I guess it is frustrating on both ends of the weight issue isn't it!

I hated being on prednisone so much because I got so emotional. I cried

during commercials on TV!!! I don't ever want to go on it again if I can

help it.

Sorry you have to endure it.

[Guest guest]

,

What stage are you at? I gained so much weight right before diagnosis

(45lbs), the doc said this was one of the side affects of the disease, I

wasn't on any meds then. Now almost three years later and they are telling

me I will need dialysis by this time next year I am shedding pounds like

crazy (4 pants sizes and 30lbs in two months).

Just wondering if this is normal as you get closer to renal failure. One

more thing, when you get to the end stages does everyone lose urination or

does it vary. I have noticed that even with the water pills I am going less

often and less volumn when I do go. Before it was every fifteen minutes

until about 1:00 in the afternoon when the pill would begin to wear off.

I love this site so much, you are all so wonderful and helpful.

CC in Idaho

Re: Prednisolone side effects? AH!!!!!!!!

> I wish it was that easy! My husband is telling me I look anorexic lately!

I

> have been trying to pump up the caloric intake recently.

>

> I guess it is frustrating on both ends of the weight issue isn't it!

>

> I hated being on prednisone so much because I got so emotional. I cried

> during commercials on TV!!! I don't ever want to go on it again if I can

> help it.

>

> Sorry you have to endure it.

>

>

>

>

>

[Guest guest]

Hi CC

What happens to urination as you approach the need for dialysis varies a

lot. Some people urinate less and less, and therefore gain weight from fluid

retention (which a loop diuretic can take care of). As I said in another

message, the part of the nephrons where urine is concentrated is different

than where the filtration is done. How much urine you produce depends on how

much function there is at that level. This isn't really related to your %

kidney function (since that is a measure of filtration, not urine

production). So, some people retain more ability to urinate than others. It

can be misleading though to judge by how often you urinate. It's not the

timing that matters but the amount of urine in a 24 hour period. It can be

interesting to measure exactly how much by doing your own 24 hour

collection.

No matter how much you urinate when you start dialysis, you urinate less and

less after that point.

Pierre

Re: Prednisolone side effects? AH!!!!!!!!

> ,

>

> What stage are you at? I gained so much weight right before diagnosis

> (45lbs), the doc said this was one of the side affects of the disease, I

> wasn't on any meds then. Now almost three years later and they are

telling

> me I will need dialysis by this time next year I am shedding pounds like

> crazy (4 pants sizes and 30lbs in two months).

>

> Just wondering if this is normal as you get closer to renal failure. One

> more thing, when you get to the end stages does everyone lose urination or

> does it vary. I have noticed that even with the water pills I am going

less

> often and less volumn when I do go. Before it was every fifteen minutes

> until about 1:00 in the afternoon when the pill would begin to wear off.

>

> I love this site so much, you are all so wonderful and helpful.

>

> CC in Idaho

[Guest guest]

Well, I'm up the other end of the scale,

unfortunately, being around 200 pounds. Even when I

had no appetite with the cellulitis, I still couldn't

get any of the stupid weight to budge!! I definetly

wish I had your problem!! And I'm as emotional as

hell, not sleeping, etc. It's driving me nuts!!

--- W4JC@... wrote: > I wish it was that

easy! My husband is telling me I

> look anorexic lately! I

> have been trying to pump up the caloric intake

> recently.

>

> I guess it is frustrating on both ends of the weight

> issue isn't it!

>

> I hated being on prednisone so much because I got so

> emotional. I cried

> during commercials on TV!!! I don't ever want to go

> on it again if I can

> help it.

>

> Sorry you have to endure it.

>

>

>

>

> [Non-text portions of this message have been

> removed]

>

>

http://greetings.yahoo.com.au - Yahoo! Greetings

- Send your seasons greetings online this year!

[Guest guest]

Jennie,

How long do you have to be on prednisolone? I feel so bad for you because

like you, I also really suffered with the side effects. I hated the not

feeling like my emotions were in control and I hated the insomnia too. I

hope you can wean down quickly. I only stayed on it a couple of months then

I told my Neph it was a quality of life issue and that I never wanted to take

it again.

Earlier this year, he asked me to consider trying it again, and I said I just

did NOT want to unless I had absolutely no choice. I hated the stuff, and I

am so sorry you are having to take it now.

[Guest guest]

Yep, I have to say the word anorexic and Connie have never been linked

together either...BUTT, look at it this way Jennie there is just more of us

to S P R E A D around! (Sorry, sometimes I just can't help myself!) Connie,

USA

Re: Prednisolone side effects? AH!!!!!!!!

Well, I'm up the other end of the scale,

unfortunately, being around 200 pounds. Even when I

had no appetite with the cellulitis, I still couldn't

get any of the stupid weight to budge!! I definetly

wish I had your problem!! And I'm as emotional as

hell, not sleeping, etc. It's driving me nuts!!

--- W4JC@... wrote: > I wish it was that

easy! My husband is telling me I

> look anorexic lately! I

> have been trying to pump up the caloric intake

> recently.

>

> I guess it is frustrating on both ends of the weight

> issue isn't it!

>

> I hated being on prednisone so much because I got so

> emotional. I cried

> during commercials on TV!!! I don't ever want to go

> on it again if I can

> help it.

>

> Sorry you have to endure it.

>

>

>

>

> [Non-text portions of this message have been

> removed]

>

>

http://greetings.yahoo.com.au - Yahoo! Greetings

- Send your seasons greetings online this year!

To edit your settings for the group, go to our Yahoo Group

home page:

http://groups.yahoo.com/group/iga-nephropathy/

Visit our companion website at www.igan.ca

[Guest guest]

That's OK, Connie, I'm actually sitting here laughing at that comment!! I'm

certainly not the sort of person who will ever be anorexic either!! LOL

Connie Sink wrote:Yep, I have to say the word anorexic

and Connie have never been linked

together either...BUTT, look at it this way Jennie there is just more of us

to S P R E A D around! (Sorry, sometimes I just can't help myself!) Connie,

USA

Re: Prednisolone side effects? AH!!!!!!!!

Well, I'm up the other end of the scale,

unfortunately, being around 200 pounds. Even when I

had no appetite with the cellulitis, I still couldn't

get any of the stupid weight to budge!! I definetly

wish I had your problem!! And I'm as emotional as

hell, not sleeping, etc. It's driving me nuts!!

--- W4JC@... wrote: > I wish it was that

easy! My husband is telling me I

> look anorexic lately! I

> have been trying to pump up the caloric intake

> recently.

>

> I guess it is frustrating on both ends of the weight

> issue isn't it!

>

> I hated being on prednisone so much because I got so

> emotional. I cried

> during commercials on TV!!! I don't ever want to go

> on it again if I can

> help it.

>

> Sorry you have to endure it.

>

>

>

>

> [Non-text portions of this message have been

> removed]

>

>

http://greetings.yahoo.com.au - Yahoo! Greetings

- Send your seasons greetings online this year!

To edit your settings for the group, go to our Yahoo Group

home page:

http://groups.yahoo.com/group/iga-nephropathy/

Visit our companion website at www.igan.ca

[Guest guest]

Connie,

You are really clever with words, I wouldn't like to be in an

argument with you!.

Derrick

Sydney Australia

> I wish it was that

> easy! My husband is telling me I

> > look anorexic lately! I

> > have been trying to pump up the caloric intake

> > recently.

> >

> > I guess it is frustrating on both ends of the weight

> > issue isn't it!

> >

> > I hated being on prednisone so much because I got so

> > emotional. I cried

> > during commercials on TV!!! I don't ever want to go

> > on it again if I can

> > help it.

> >

> > Sorry you have to endure it.

> >

> >

> >

> >

> > [Non-text portions of this message have been

> > removed]

> >

> >

>

> http://greetings.yahoo.com.au - Yahoo! Greetings

> - Send your seasons greetings online this year!

>

> To edit your settings for the group, go to our Yahoo Group

> home page:

> http://groups.yahoo.com/group/iga-nephropathy/

> Visit our companion website at www.igan.ca

>

>

[Guest guest]

Funny you should say that Derrick. I was representing management on our

negotiating teams for the collective bargaining agreements this last year at

work! So you might say I have a lot of experience with arguing! Connie,

USA

Re: Prednisolone side effects? AH!!!!!!!!

Connie,

You are really clever with words, I wouldn't like to be in an

argument with you!.

Derrick

Sydney Australia

> I wish it was that

> easy! My husband is telling me I

> > look anorexic lately! I

> > have been trying to pump up the caloric intake

> > recently.

> >

> > I guess it is frustrating on both ends of the weight

> > issue isn't it!

> >

> > I hated being on prednisone so much because I got so

> > emotional. I cried

> > during commercials on TV!!! I don't ever want to go

> > on it again if I can

> > help it.

> >

> > Sorry you have to endure it.

> >

> >

> >

> >

> > [Non-text portions of this message have been

> > removed]

> >

> >

>

> http://greetings.yahoo.com.au - Yahoo! Greetings

> - Send your seasons greetings online this year!

>

> To edit your settings for the group, go to our Yahoo Group

> home page:

> http://groups.yahoo.com/group/iga-nephropathy/

> Visit our companion website at www.igan.ca

>

>

[Guest guest]

I'll be on it for another week and a half, it's just long enough to settle the

asthma down a bit. I've started tapering off it today.

W4JC@... wrote:Jennie,

How long do you have to be on prednisolone? I feel so bad for you because

like you, I also really suffered with the side effects. I hated the not

feeling like my emotions were in control and I hated the insomnia too. I

hope you can wean down quickly. I only stayed on it a couple of months then

I told my Neph it was a quality of life issue and that I never wanted to take

it again.

Earlier this year, he asked me to consider trying it again, and I said I just

did NOT want to unless I had absolutely no choice. I hated the stuff, and I

am so sorry you are having to take it now.

[Guest guest]

Jennie,

Thank goodness you don't have to be on it long! I am so glad you already get

to taper down. I hope the lower dose eases the side effects for you.

[Guest guest]

Hi Jennie,

That is the side effect I hated the most! It is awful to not feel like you

have control over your emotions. I hope I never ever have to take

Prednisolone again. How many weeks to taper you down?

[Guest guest]

I'm now down to 30mg/day, but the side effects are still driving me up the wall,

unfortunately. I seem to cry over the silliest things. I can't wait to get off

the stuff altogether.

W4JC@... wrote:Jennie,

Thank goodness you don't have to be on it long! I am so glad you already get

to taper down. I hope the lower dose eases the side effects for you.

[Guest guest]

Jennie,

Having been through a deep deep depression myself, I can sure identify with

this one! Glad to know you will be off by New Years. That will definitely

give you something to celebrate!!

[Guest guest]

I will be off the prednisolone completely by New Years Eve, thank goodness. I

definetly hate that side effect, especially seeing as I suffer from depression

anyway. At least I haven't thought about trying to do anything stupid, unlike

when my depression was first diagnosed.

W4JC@... wrote:Hi Jennie,

That is the side effect I hated the most! It is awful to not feel like you

have control over your emotions. I hope I never ever have to take

Prednisolone again. How many weeks to taper you down?