Guest guest Posted December 4, 2006 Report Share Posted December 4, 2006 Here's a recent article (Oct 26, 06) to follow up on the natural breast enlargement experiment in Japan. Bold highlights are mine: http://www.stemcellresearchnews.com/absolutenm/anmviewer.asp?a=333 & z=5 Fat-Derived Stem Cells Succeed In Reconstructive SurgeryThursday, October 26, 2006 - Stem Cell Research News Adipose tissue, also known as fat, has been found to be a rich source of stem cells as well as other cell types that contribute to the natural healing process in humans. Known as adipose-derived stem cells, researchers have prompted them to convert to fat, bone, cartilage and muscle and believe these cells could help treat heart conditions, heal broken bones, and even be used in reconstructive surgery. Now stem cells derived from human fat tissue have shown early success in reconstructive surgeries in more than 30 patients in Japan who underwent facial and breast procedures, it was reported October 24. The results from an investigator-initiated study by Dr. Kotaro Yoshimura of Tokyo University in Japan were presented today at the annual meeting of the International Fat Applied Technology Society in Baton Rouge, Louisiana. Yoshimura performed an innovative stem cell treatment on 39 patients who underwent procedures ranging from repair of congenital facial and breast defects, aesthetic enhancements to breast reconstruction following partial mastectomy. The procedure is similar to a conventional lipo-injection. Yoshimura’s team lipo-suctioned fat from his patients, concentrated stem cells found in the fat, then injected the fat and stem cells into the areas of damaged tissue. Each patient received his or her own fat and stem cells. Until now, doctors have injected fat into damaged tissue to give physical or mechanical support. However, eventual loss of that fat, called atrophy, is now a common occurrence in patients who have had injected fat therapy. Yoshimura observed minimal atrophy in his patients, and believes the stem cells were a key to keeping fat healthy and allowing it to rejuvenate. “Stem cells derived from fat tissue appear to act through the promotion of blood vessels as a way to increase the survival of the transplanted tissue as well as continue to tissue turnover after transplantation by forming new fat cells, helping to preserve tissue volume,” said Yoshimura. “These are early findings for which more research is required prior to making such a treatment broadly available, however these clinical results demonstrate the potential for stem cells derived from fat tissue.” Yoshimura also said that 70-percent of all complications arising from cosmetic surgery are linked to use of artificial materials. Stem cell enriched-fat, therefore, holds the promise of eliminating those complications. “Fat is considered to be much more than just those extra pounds we carry around,” said Dr. Gimble of the Pennington Biomedical Research Center in Baton Rouge. “It’s a dynamic tissue that holds secrets to treating disease. Unlocking the potential of stem cells found in fat tissue is just the beginning.” Meanwhile, a separate research team led by Lorenza Lazzari, Ph.D., released work that supports the thought that fat stem cells within transplanted fat can improve lipo-injection therapy. Lazzari’s team extracted patients’ fat from their abdomen and thigh (lipo-suction) from 12 patients and then injected the fat into patients’ vocal folds. This therapy is used following damage due to disease or anatomical defect. Until now, the team believed the injected fat offered only mechanical or structural support of the vocal folds. Prior to injection, however, the team also sampled the fat for laboratory analysis. Lazzari’s team found that this procedure gave vocal abilities and normal speech to their patient for the long-term – 1 to two years so far. The injected fat remained healthier and showed rejuvenation. To determine why, the team analyzed the fat tissue used for injection and found the presence of stem cells. Lazzari believes that adult stem cells (ASCs) residing naturally in fat tissue may enhance the rejuvenation of damaged vocal folds. Sample analysis indicated that ASCs in fat samples were present and able to differentiate into various cell types and may act as a source to provide regenerative abilities in vocal fold tissue. The International Fat Applied Technology Society brings together different disciplines within the field in order to share knowledge, influence policy and exchange new ideas. Turning Fat Stem Cells Into Pre-Fat Cells Another fat-related finding released October 24 showed a human virus targets fat stem cells to cause formation of more, fatter, fat cells. The finding may lead to new insights into the study of obesity, according to researchers. Magdalena Pasarica, Ph.D., released her new work on the fat-targeting virus at the IFATS meeting. Pasarica is a researcher with the Pennington Biomedical Research Center. She has been studying human adenovirus-36 (Ad-36) role in human obesity. Adenoviruses are the same viruses that cause colds. Earlier researchers have concluded that Ad-36 may be contributors to obesity by super-charging fat cells to grow store more fat. Until now, though, those researchers thought the viruses targeted “pre-fat” cells (called pre-adipocytes), causing them to convert in higher numbers to fat cells and causing those fat cells to be larger. Those studies were in mice. Pasarica’s work determines the virus targets stem cells in humans. Her research shows the virus goes to work before the formation of human pre-fat cells by targeting the stem cells that would eventually convert to pre-fat cells. The virus causes more stem cells to convert to pre-fat cells and causes the pre-fat cells to become bigger fat cells.Contact: http://www.ifats.org Related Articles : Breast Reconstruction Patients Treated In Adipose SC Safety Study (Tuesday, June 20, 2006)A San Diego, Calif.-based company said on June 1 that it has treated the first three patients in a study using adult adipose-derived stem and regenerative cells for breast reconstruction cancer therapy. Cambrex, Cytori To Provide Adipose Derived Stem Cell Research Products (June 13, 2006)Cambrex Bio Science sville and Cytori Therapeutics announced an agreement to provide adipose (fat)-derived stem cell products globally for use in basic and translational bioresearch. Company’s Fat-Derived Stem Cell Solution Found Effective In Treating Coronary Artery Disease (Monday, July 17, 2006)Adipose-derived stem and regenerative cells safely improved heart function in laboratory pigs with a severe form of coronary artery disease. Researchers Transform Fat-Derived Stem Cells Into Muscle Cells (Monday, July 24, 2006)Adult stem cells taken from human adipose, or fat, tissue have been transformed into smooth muscle cells found in many organs, including the intestine, bladder and arteries. Company Says Fat-Based Stem Cell Technology Moving To Clinical Trials (Monday, September 11, 2006)A California company headed by a plastic surgeon says its fat-based stem cell technology is moving to clinical trials. Japan: Stem cells and fat for natural breast enlargement The date is almost 3 years old on this article. I wonder what has happened since then? http://www.medicaln ewstoday. com/medicalnews. php?newsid= 5796 Natural breast implants from stem cells and woman’s own fat - JapanMain Category: Public Health NewsArticle Date: 09 Feb 2004 - 0:00am (PST)| email this article | printer friendly | view or write opinions | In Japan, scientists (University of Tokyo) can make natural breast implants by using a combination of a woman’s own fat and stem cells. This will be far more desirable than having artificial implants made of salt water or silicone. No one has so far succeeded in increasing breast size with fat. Lots of the tissue dies and the breast ends up with hard lumps. The scientists say that if you add stem cells you then encourage the growth of new blood vessels. Another problem with using fat for breast implants is the amount of fat required (a great deal more than for other cosmetic surgeries). According to Dr. Kotaro Yoshimura (team leader), his team have found a way of enlarging breasts without all the complications. They suck fat from the patient’s stomach (or thigh). The fat slurry is enriched with a higher than normal number of stem cells. These ‘master cells’ are able to create new fat cells. When the mixture is ready (combined) it is injected into the breast area. The woman could be killing two birds with one stone. Not only will she be getting larger breasts, but she will also be losing fat in other parts of her body. Another advantage of this procedure is that there is no risk of rejection by the patient’s immune system. This procedure has already been carried out on one patient in Japan (last month). The team who did this hope to carry out many more operations. Other doctors have called for more animal trials before operating in large numbers on humans. Access over 1 million songs - Music Unlimited. Want to start your own business? Learn how on Small Business. 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Guest guest Posted December 4, 2006 Report Share Posted December 4, 2006 I've heard that fat is being transfered, with it's natural blood supply to the breast for reconstruction . . . microsurgery. It takes a very well trained surgeon. Dr. Feng alluded to in in one of her articles. Rogene Tricia Trish <glory2glory1401@...> wrote: Here's a recent article (Oct 26, 06) to follow up on the natural breast enlargement experiment in Japan. Bold highlights are mine: http://www.stemcellresearchnews.com/absolutenm/anmviewer.asp?a=333 & z=5 Fat-Derived Stem Cells Succeed In Reconstructive SurgeryThursday, October 26, 2006 - Stem Cell Research News Adipose tissue, also known as fat, has been found to be a rich source of stem cells as well as other cell types that contribute to the natural healing process in humans. Known as adipose-derived stem cells, researchers have prompted them to convert to fat, bone, cartilage and muscle and believe these cells could help treat heart conditions, heal broken bones, and even be used in reconstructive surgery. Now stem cells derived from human fat tissue have shown early success in reconstructive surgeries in more than 30 patients in Japan who underwent facial and breast procedures, it was reported October 24. The results from an investigator-initiated study by Dr. Kotaro Yoshimura of Tokyo University in Japan were presented today at the annual meeting of the International Fat Applied Technology Society in Baton Rouge, Louisiana. Yoshimura performed an innovative stem cell treatment on 39 patients who underwent procedures ranging from repair of congenital facial and breast defects, aesthetic enhancements to breast reconstruction following partial mastectomy. The procedure is similar to a conventional lipo-injection. Yoshimura’s team lipo-suctioned fat from his patients, concentrated stem cells found in the fat, then injected the fat and stem cells into the areas of damaged tissue. Each patient received his or her own fat and stem cells. Until now, doctors have injected fat into damaged tissue to give physical or mechanical support. However, eventual loss of that fat, called atrophy, is now a common occurrence in patients who have had injected fat therapy. Yoshimura observed minimal atrophy in his patients, and believes the stem cells were a key to keeping fat healthy and allowing it to rejuvenate. “Stem cells derived from fat tissue appear to act through the promotion of blood vessels as a way to increase the survival of the transplanted tissue as well as continue to tissue turnover after transplantation by forming new fat cells, helping to preserve tissue volume,” said Yoshimura. “These are early findings for which more research is required prior to making such a treatment broadly available, however these clinical results demonstrate the potential for stem cells derived from fat tissue.” Yoshimura also said that 70-percent of all complications arising from cosmetic surgery are linked to use of artificial materials. Stem cell enriched-fat, therefore, holds the promise of eliminating those complications. “Fat is considered to be much more than just those extra pounds we carry around,” said Dr. Gimble of the Pennington Biomedical Research Center in Baton Rouge. “It’s a dynamic tissue that holds secrets to treating disease. Unlocking the potential of stem cells found in fat tissue is just the beginning.” Meanwhile, a separate research team led by Lorenza Lazzari, Ph.D., released work that supports the thought that fat stem cells within transplanted fat can improve lipo-injection therapy. Lazzari’s team extracted patients’ fat from their abdomen and thigh (lipo-suction) from 12 patients and then injected the fat into patients’ vocal folds. This therapy is used following damage due to disease or anatomical defect. Until now, the team believed the injected fat offered only mechanical or structural support of the vocal folds. Prior to injection, however, the team also sampled the fat for laboratory analysis. Lazzari’s team found that this procedure gave vocal abilities and normal speech to their patient for the long-term – 1 to two years so far. The injected fat remained healthier and showed rejuvenation. To determine why, the team analyzed the fat tissue used for injection and found the presence of stem cells. Lazzari believes that adult stem cells (ASCs) residing naturally in fat tissue may enhance the rejuvenation of damaged vocal folds. Sample analysis indicated that ASCs in fat samples were present and able to differentiate into various cell types and may act as a source to provide regenerative abilities in vocal fold tissue. The International Fat Applied Technology Society brings together different disciplines within the field in order to share knowledge, influence policy and exchange new ideas. Turning Fat Stem Cells Into Pre-Fat Cells Another fat-related finding released October 24 showed a human virus targets fat stem cells to cause formation of more, fatter, fat cells. The finding may lead to new insights into the study of obesity, according to researchers. Magdalena Pasarica, Ph.D., released her new work on the fat-targeting virus at the IFATS meeting. Pasarica is a researcher with the Pennington Biomedical Research Center. She has been studying human adenovirus-36 (Ad-36) role in human obesity. Adenoviruses are the same viruses that cause colds. Earlier researchers have concluded that Ad-36 may be contributors to obesity by super-charging fat cells to grow store more fat. Until now, though, those researchers thought the viruses targeted “pre-fat” cells (called pre-adipocytes), causing them to convert in higher numbers to fat cells and causing those fat cells to be larger. Those studies were in mice. Pasarica’s work determines the virus targets stem cells in humans. Her research shows the virus goes to work before the formation of human pre-fat cells by targeting the stem cells that would eventually convert to pre-fat cells. The virus causes more stem cells to convert to pre-fat cells and causes the pre-fat cells to become bigger fat cells.Contact: http://www.ifats.org Related Articles : Breast Reconstruction Patients Treated In Adipose SC Safety Study (Tuesday, June 20, 2006)A San Diego, Calif.-based company said on June 1 that it has treated the first three patients in a study using adult adipose-derived stem and regenerative cells for breast reconstruction cancer therapy. Cambrex, Cytori To Provide Adipose Derived Stem Cell Research Products (June 13, 2006)Cambrex Bio Science sville and Cytori Therapeutics announced an agreement to provide adipose (fat)-derived stem cell products globally for use in basic and translational bioresearch. Company’s Fat-Derived Stem Cell Solution Found Effective In Treating Coronary Artery Disease (Monday, July 17, 2006)Adipose-derived stem and regenerative cells safely improved heart function in laboratory pigs with a severe form of coronary artery disease. Researchers Transform Fat-Derived Stem Cells Into Muscle Cells (Monday, July 24, 2006)Adult stem cells taken from human adipose, or fat, tissue have been transformed into smooth muscle cells found in many organs, including the intestine, bladder and arteries. Company Says Fat-Based Stem Cell Technology Moving To Clinical Trials (Monday, September 11, 2006)A California company headed by a plastic surgeon says its fat-based stem cell technology is moving to clinical trials. Japan: Stem cells and fat for natural breast enlargement The date is almost 3 years old on this article. I wonder what has happened since then? http://www.medicaln ewstoday. com/medicalnews. php?newsid= 5796 Natural breast implants from stem cells and woman’s own fat - JapanMain Category: Public Health NewsArticle Date: 09 Feb 2004 - 0:00am (PST)| email this article | printer friendly | view or write opinions | In Japan, scientists (University of Tokyo) can make natural breast implants by using a combination of a woman’s own fat and stem cells. This will be far more desirable than having artificial implants made of salt water or silicone. No one has so far succeeded in increasing breast size with fat. Lots of the tissue dies and the breast ends up with hard lumps. The scientists say that if you add stem cells you then encourage the growth of new blood vessels. Another problem with using fat for breast implants is the amount of fat required (a great deal more than for other cosmetic surgeries). According to Dr. Kotaro Yoshimura (team leader), his team have found a way of enlarging breasts without all the complications. They suck fat from the patient’s stomach (or thigh). The fat slurry is enriched with a higher than normal number of stem cells. These ‘master cells’ are able to create new fat cells. When the mixture is ready (combined) it is injected into the breast area. The woman could be killing two birds with one stone. Not only will she be getting larger breasts, but she will also be losing fat in other parts of her body. Another advantage of this procedure is that there is no risk of rejection by the patient’s immune system. This procedure has already been carried out on one patient in Japan (last month). The team who did this hope to carry out many more operations. Other doctors have called for more animal trials before operating in large numbers on humans. Access over 1 million songs - Music Unlimited. Want to start your own business? Learn how on Small Business. 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Guest guest Posted December 5, 2006 Report Share Posted December 5, 2006 Yes, but Dr. Feng also takes some muscle with it. Lynda At 01:39 PM 12/4/2006, you wrote: >I've heard that fat is being transfered, with >it's natural blood supply to the breast for >reconstruction . . . microsurgery. It takes a >very well trained surgeon. Dr. Feng alluded to in in one of her articles. > >Rogene > > > >Tricia Trish <glory2glory1401@...> wrote: >Here's a recent article (Oct 26, 06) to follow >up on the natural breast enlargement experiment >in Japan. Bold highlights are mine: ><http://www.stemcellresearchnews.com/absolutenm/anmviewer.asp?a=333 & z=5>http://\ www.stemcellresearchnews.com/absolutenm/anmviewer.asp?a=333 & z=5 >Fat-Derived Stem Cells Succeed In Reconstructive Surgery >Thursday, October 26, 2006 - Stem Cell Research News >Adipose tissue, also known as fat, has been >found to be a rich source of stem cells as well >as other cell types that contribute to the natural healing process in humans. >Known as adipose-derived stem cells, researchers >have prompted them to convert to fat, bone, >cartilage and muscle and believe these cells >could help treat heart conditions, heal broken >bones, and even be used in reconstructive surgery. >Now stem cells derived from human fat tissue >have shown early success in reconstructive >surgeries in more than 30 patients in Japan who >underwent facial and breast procedures, it was reported October 24. >The results from an investigator-initiated study >by Dr. Kotaro Yoshimura of Tokyo University in >Japan were presented today at the annual meeting >of the International Fat Applied Technology Society in Baton Rouge, Louisiana. >Yoshimura performed an innovative stem cell >treatment on 39 patients who underwent >procedures ranging from repair of congenital >facial and breast defects, aesthetic >enhancements to breast reconstruction following partial mastectomy. >The procedure is similar to a conventional >lipo-injection. Yoshimura’s team lipo-suctioned >fat from his patients, concentrated stem cells >found in the fat, then injected the fat and stem >cells into the areas of damaged tissue. >Each patient received his or her own fat and stem cells. >Until now, doctors have injected fat into >damaged tissue to give physical or mechanical support. >However, eventual loss of that fat, called >atrophy, is now a common occurrence in patients >who have had injected fat therapy. >Yoshimura observed minimal atrophy in his >patients, and believes the stem cells were a key >to keeping fat healthy and allowing it to rejuvenate. >“Stem cells derived from fat tissue appear to >act through the promotion of blood vessels as a >way to increase the survival of the transplanted >tissue as well as continue to tissue turnover >after transplantation by forming new fat cells, >helping to preserve tissue volume,” said >Yoshimura. “These are early findings for which >more research is required prior to making such a >treatment broadly available, however these >clinical results demonstrate the potential for >stem cells derived from fat tissue.” >Yoshimura also said that 70-percent of all >complications arising from cosmetic surgery are >linked to use of artificial materials. >Stem cell enriched-fat, therefore, holds the >promise of eliminating those complications. >“Fat is considered to be much more than just >those extra pounds we carry around,” said Dr. > Gimble of the Pennington Biomedical >Research Center in Baton Rouge. “It’s a dynamic >tissue that holds secrets to treating disease. >Unlocking the potential of stem cells found in >fat tissue is just the beginning.” >Meanwhile, a separate research team led by >Lorenza Lazzari, Ph.D., released work that >supports the thought that fat stem cells within >transplanted fat can improve lipo-injection therapy. >Lazzari’s team extracted patients’ fat from >their abdomen and thigh (lipo-suction) from 12 >patients and then injected the fat into patients’ vocal folds. >This therapy is used following damage due to disease or anatomical defect. >Until now, the team believed the injected fat >offered only mechanical or structural support of the vocal folds. >Prior to injection, however, the team also >sampled the fat for laboratory analysis. >Lazzari’s team found that this procedure gave >vocal abilities and normal speech to their >patient for the long-term – 1 to two years so far. >The injected fat remained healthier and showed rejuvenation. >To determine why, the team analyzed the fat >tissue used for injection and found the presence of stem cells. >Lazzari believes that adult stem cells (ASCs) >residing naturally in fat tissue may enhance the >rejuvenation of damaged vocal folds. >Sample analysis indicated that ASCs in fat >samples were present and able to differentiate >into various cell types and may act as a source >to provide regenerative abilities in vocal fold tissue. >The International Fat Applied Technology Society >brings together different disciplines within the >field in order to share knowledge, influence policy and exchange new ideas. >Turning Fat Stem Cells Into Pre-Fat Cells >Another fat-related finding released October 24 >showed a human virus targets fat stem cells to >cause formation of more, fatter, fat cells. >The finding may lead to new insights into the >study of obesity, according to researchers. >Magdalena Pasarica, Ph.D., released her new work >on the fat-targeting virus at the IFATS meeting. >Pasarica is a researcher with the Pennington Biomedical Research Center. >She has been studying human adenovirus-36 >(Ad-36) role in human obesity. Adenoviruses are >the same viruses that cause colds. >Earlier researchers have concluded that Ad-36 >may be contributors to obesity by super-charging >fat cells to grow store more fat. >Until now, though, those researchers thought the >viruses targeted “pre-fat” cells (called >pre-adipocytes), causing them to convert in >higher numbers to fat cells and causing those fat cells to be larger. >Those studies were in mice. >Pasarica’s work determines the virus targets stem cells in humans. >Her research shows the virus goes to work before >the formation of human pre-fat cells by >targeting the stem cells that would eventually convert to pre-fat cells. >The virus causes more stem cells to convert to >pre-fat cells and causes the pre-fat cells to become bigger fat cells. >Contact: <http://www.ifats.org/>http://www.ifats.org > >Related Articles : ><http://www.stemcellresearchnews.com/absolutenm/anmviewer.asp?a=16 & z=5>Breast >Reconstruction Patients Treated In Adipose SC >Safety Study (Tuesday, June 20, 2006) >A San Diego, Calif.-based company said on June 1 >that it has treated the first three patients in >a study using adult adipose-derived stem and >regenerative cells for breast reconstruction cancer therapy. ><http://www.stemcellresearchnews.com/absolutenm/anmviewer.asp?a=26 & z=5>Cambrex, >Cytori To Provide Adipose Derived Stem Cell Research Products (June 13, 2006) >Cambrex Bio Science sville and Cytori >Therapeutics announced an agreement to provide >adipose (fat)-derived stem cell products >globally for use in basic and translational bioresearch. ><http://www.stemcellresearchnews.com/absolutenm/anmviewer.asp?a=62 & z=5>Company’\ s >Fat-Derived Stem Cell Solution Found Effective >In Treating Coronary Artery Disease (Monday, July 17, 2006) >Adipose-derived stem and regenerative cells >safely improved heart function in laboratory >pigs with a severe form of coronary artery disease. ><http://www.stemcellresearchnews.com/absolutenm/anmviewer.asp?a=87 & z=5>Research\ ers >Transform Fat-Derived Stem Cells Into Muscle Cells (Monday, July 24, 2006) >Adult stem cells taken from human adipose, or >fat, tissue have been transformed into smooth >muscle cells found in many organs, including the >intestine, bladder and arteries. ><http://www.stemcellresearchnews.com/absolutenm/anmviewer.asp?a=240 & z=5>Company >Says Fat-Based Stem Cell Technology Moving To >Clinical Trials (Monday, September 11, 2006) >A California company headed by a plastic surgeon >says its fat-based stem cell technology is moving to clinical trials. > > Japan: Stem cells and >fat for natural breast enlargement > > > >The date is almost 3 years old on this >article. I wonder what has happened since then? > > > > > ><http://www.medicalnewstoday.com/medicalnews.php?newsid=5796>http://www.medical\ n >ewstoday. com/medicalnews. php?newsid= 5796 > > > >Natural breast implants from stem cells and woman’s own fat - Japan >Main Category: ><http://www.medicalnewstoday.com/sections/public_health/>Public Health News >Article Date: 09 Feb 2004 - 0:00am (PST) >| email this article | printer friendly | ><http://www.medicalnewstoday.com/youropinions.php?associatednewsid=5796>view >or write opinions | > >In Japan, scientists (University of Tokyo) can >make natural breast implants by using a >combination of a woman’s own fat and stem cells. > >This will be far more desirable than having >artificial implants made of salt water or silicone. > >No one has so far succeeded in increasing breast >size with fat. Lots of the tissue dies and the breast ends up with hard lumps. > >The scientists say that if you add stem cells >you then encourage the growth of new blood vessels. > >Another problem with using fat for breast >implants is the amount of fat required (a great >deal more than for other cosmetic surgeries). > >According to Dr. Kotaro Yoshimura (team leader), >his team have found a way of enlarging breasts without all the complications. > >They suck fat from the patient’s stomach (or >thigh). The fat slurry is enriched with a higher >than normal number of stem cells. These ‘master >cells’ are able to create new fat cells. > >When the mixture is ready (combined) it is injected into the breast area. > >The woman could be killing two birds with one >stone. Not only will she be getting larger >breasts, but she will also be losing fat in other parts of her body. > >Another advantage of this procedure is that >there is no risk of rejection by the patient’s immune system. > >This procedure has already been carried out on >one patient in Japan (last month). The team who >did this hope to carry out many more operations. > >Other doctors have called for more animal trials >before operating in large numbers on humans. > > > >Access over 1 million songs - ><http://pa./*http://us.rd./evt=36035/*http://music./\ unlimited/> >Music Unlimited. > > > >Want to start your own business? Learn how on ><http://us.rd./evt=41244/*http://smallbusiness./r-index>\ ! >Small Business. > > > Quote Link to comment Share on other sites More sharing options...
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