Guest guest Posted June 4, 2008 Report Share Posted June 4, 2008 OK--BEFORE YOU START DRINKING YOUR PEE, PLEASE READ THE FOLLOWING!!!! This first site lists about 8 studies done with uric acid levels in MS: http://www.geocities.com/hotsprings/3468/uric_acid-peroxynitrite2- 98.html#3 This second site speaks to a study giving Inosine to MS patients to raise uric acid levels: http://www.ncbi.nlm.nih.gov/pubmed/11724447?dopt=Abstract After reading all this, I located the email address of one of the men involved in the study and, in March, I wrote to him. Following is my email and his response. Original message:Beverly Hammons Sent: Thursday, March 20, 2008 9:14 PM To: c_hooper@... Subject: inosine in multiple sclerosis study Dr. Hooper; I hope you don't mind my contacting you. I have MS and I am interested in taking inosine which you used in your study to raise uric acid levels. But no matter how many websites I look at, I cannot find the amount of inosine you used. Could you please tell me how much inosine produced these beneficial results? Thank you very much for your time. Beverly Hammons RESPONSE: Dear Beverly, Unfortunately the amount that we give is different for different individuals, depending on how low their serum urate is to begin with, and how they metabolize inosine/urate. We try to achieve serum urate levels of around 6 mg/dL which is the normal range for men (they have higher serum urate than women). If the levels get too high there is a chance of getting kidney stones so we are very careful in measuring serum urate levels routinely. We generally use 2-3 gm per day in two doses, morning and late afternoon, taken with water or juice – proper hydration is important. It is always best to know what your serum urate levels are before taking inosine although the low doses taken by bodybuilders have not been reported to have any adverse effect. Best wishes, Craig Hooper, Ph.D. Associate Director, Center for Neurovirology Associate Professor, Departments of Cancer Biology and Neurological Surgery Jefferson University 1020 Locust Street, JAH 452 Philadelphia, PA 19107-6731 office: lab: fax: I was pleasantly surprised that he actually answered me. I had my uric acid levels checked: they weren't real low, but they weren't all that high either, so I decided it would be OK to take Inosine. I take 2 grams/day, empty stomach with water. I will have my levels rechecked. Hope you find all this helpful. Beverly > > Beverly, > > Thanks. I noticed the same thing in an article where they used up to 3 grams > for long durations with no known side effects. I just started taking about 2 > grams and will go up to 3 today. > > I also here uric acid is a potent peroxinite scavenger and b 12 only in the > hydroxocobolamin form is a potent nitric oxide (NO) scavenger. Much more > potent in a nebulized dose as compared to oral. As for the uric acid, don't know > where or how to utilize that unless you want to drink your own pee. (LOL) > > > In a message dated 6/2/2008 11:01:55 P.M. Pacific Daylight Time, > beebie10@... writes: > > > > > First I need to apologize; evidently I sent the same post yesterday > THREE TIMES!!(blame it on brain fog!)SORRY. > > Glenn > -regarding acetyl-l-Carnitine: I just re-read the following sites and > I got inspired all over again. There are so many things " alcar " can > do for us MSer's; it sounds amazing. I am also intrigued as it might > help my long standing depression. > > Anyway, I don't know what the Maximum dose is. I will continue > research. But the studies listed in the sites below used 2 to 3 grams > per day. I would think in divided doses. I did see a note that high > doses may cause nausea, but I've been taking 2 grams/day for about 10 > days now and I haven't noticed anything. After reading the studies, I > think I'm going to increase to 3 grams starting tomorrow. > > Remember amino acids must be taken on an empty stomach if using > therapeutically. > > Beverly > > _http://findarticleshttp://findartichttp://fihttp://findarti_ > (http://findarticles.com/p/articles/mi_m0ISW/is_2002_August-) > Sept/ai_90794458 > > _http://www.lef.http://www.lehttp://www.lef.http://www.lef.http://_ > (http://www.lef.org/magazine/mag2006/sep2006_report_carnitine_01.htm) > > _http://www.raysahelhttp://www.raysahttp://www.r_ > (http://www.raysahelian.com/acetylcarnitine.html) > > > > > > > > **************Get trade secrets for amazing burgers. Watch " Cooking with > Tyler Florence " on AOL Food. > (http://food.aol.com/tyler-florence?video=4? & NCID=aolfod00030000000002) > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted June 6, 2008 Report Share Posted June 6, 2008 Hmmm...interesting. I too corresponded with the researchers. Then I did something really stupid. I found a trace mineral that raises uric acid, took it and almost killed myself. Excessive uric acid causes gout and heart problems. I found out that increased ATP levels raise uric acid seru levels natually. One of the best ways of raising ATP levels is by taking D-Ribose. One can also raise uric acid levels by increasing purines. http://askville.amazon.com/Purines-source-turned-uric-acid-body/AnswerDetails.do\ ?requestId=2773531 & responseId=2776770 . Lydia Quote Link to comment Share on other sites More sharing options...
Guest guest Posted June 6, 2008 Report Share Posted June 6, 2008 You have to ask yourself why our bodies delete uric acid? Quote Link to comment Share on other sites More sharing options...
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