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Hey Beth,

I ran across this journal abstract and I thought you might be

bolstered by how well corrected septate uteri did compared to other

mullerian anomalies... I've put *** around the key point. I wish I

had the whole article, but I'm sure you could get it from a med

school library.

~

Assisted reproduction in women with uterine anomalies.

Heinonen PK - Eur J Obstet Gynecol Reprod Biol - 2000 Apr; 89(2):

181-4

Abstract:

A retrospective analysis was performed to evaluate the reproductive

performance of 17 women with uterine anomalies who underwent in vitro

fertilization (IVF) or intracytoplasmic sperm injection (ICSI) and

embryo transfer (ET). Eight women had a unicornuate uterus, and two a

didelphic uterus. Seven women with a subseptate uterus underwent

metroplasty before assisted reproduction. Ten (58.8%) out of 17 women

achieved 11 (18.0%) pregnancies out of 61 embryo transfers in 55

stimulated cycles. The implantation rate per embryo was 8/83 (9.6%)

for women with a unicornuate uterus, one of 17 (5. 9%) for those with

didelphic uterus and four of 48 (8.3%) for those with subseptate

uterus. Pregnancy rates per embryo transfer were 19. 4, 11.1 and

19.0%, respectively. Three out of 11 pregnancies were ectopic, three

were miscarriages and five were full-term deliveries, two sets of

twins. ***Delivery rate per embryo transfer was 5.0% in patients with

unicornuate or didephic uterus and 14.3% in women who had a

subseptate uterus operated prior to assisted reproduction. Women with

uterine anomalies treated by IVF or ICSI had low implantation rates.

Pregnancy in a subseptate uterus which has been previously operated

had a trend to end more frequently in delivery than that in a

unicornuate uterus or in a didelphic uterus.***

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