Vitamin D May Protect Against Premenopausal Breast Cancer

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Vitamin D May Protect Against Premenopausal Breast Cancer

http://www.vitasearch.com/CP/weeklyupdates/

Reference: " Plasma 25-hydroxyvitamin D and premenopausal breast cancer

risk in a German case-control study, " Abbas S, Chang-Claude J, Linseisen

J, Int J Cancer, 2008 Oct 6; [Epub ahead of print]. (Address: Division

of Cancer Epidemiology, German Cancer Research Center, Heidelberg,

Germany. E-mail: Chang-Claude, j.chang-claude@... ).

Summary: In a study involving data from a population-based,

case-control study involving 289 premenopausal women with breast cancer

and 595 matched controls, a significant inverse association was found

between risk of breast cancer and plasma 25(OH)D concentrations (an

overall indicator of vitamin D status), with a stronger concentration

found in progesterone receptor negative tumors. Compared to women with

the lowest levels of plasma 25(OH)D (< 30 nmol/L), the odds ratios for

women with higher levels of plasma 25(OH)D were: 0.68 (30-45 nmol/L),

0.59 (45-60 nmol/L), and 0.45 (>/=60 nmol/L). The authors conclude, " Our

findings support a protective effect of vitamin D for premenopausal

breast cancer. "

--

ne Holden, MS, RD

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