Vitamin D is Associated with a Reduced Risk of Breast Cancer Irrespective of ER/PR Status of the Tumor

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Vitamin D is Associated with a Reduced Risk of Breast Cancer

Irrespective of ER/PR Status of the Tumor

http://www.vitasearch.com/CP/weeklyupdates/

Reference: " Vitamin D From Dietary Intake and Sunlight Exposure and the

Risk of Hormone-Receptor-Defined Breast Cancer, " Blackmore KM, Lesosky

M, et al, Am J Epidemiol, 2008 August 27; [Epub ahead of print].

(Address: a M. Blackmore, Lunenfeld Research Institute,

Mount Sinai Hospital, 60 Murray Street, Box 18, Toronto, Ontario, Canada

M5T 3L9. E-mail: blackmore@... ).

Summary: In a case-control study involving 759 women with breast cancer

and 1,135 controls, increasing intake of vitamin D (both from sun

exposure as well as from diet) was found to be associated with a reduced

risk of breast cancer, irrespective of ER/PR status of the tumor. While

the most consistent significant association was found for ER+/PR+ tumors

(OR=0.76), comparable non-significant associations were found for

ER-/PR- tumors (OR=0.74), and mixed (ER+/PR-) tumors (OR=0.79). The

authors conclude, " This study suggests that vitamin D is associated with

a reduced risk of breast cancer regardless of ER/PR status of the

tumor. " Additional research is warranted.

--

ne Holden, MS, RD

" Ask the Parkinson Dietitian " http://www.parkinson.org/

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