Re: Re: Sweaty feet/tingling in hands/feet

[Guest guest]

,

Perhaps this can help your friend: but I hope she has discontinued the

Cipro. Cipro has a reputation as being a problem in people with sulfation

problems, like people with AIDS, but you could get sulfation problems from

a recent exposure to something toxic..

One of the reasons cipro may be problematic for someone with depressed

sulfur chemistry is that it has effects upon the proteoglycan metabolism,

and that would mean it also has effects on glycosaminoglycans. For

instance, it is said that cipro can cause bone formation abnormalities in

young children.

A lot of researchers are not up enough on their sulfur biochemistry to

realize that effects on glycosaminoglycans may affect other tissues besides

cartilage and bone. I've put an article below describing cipro's effect on

the proteoglycan chemistry. It may not make sense why this could be

relevant to neurological signs if you don't know much about GAGs and

proteoglycans and how they affect the nervous system.

Perhaps a little help in that department would come from reading an article

I wrote four years ago about glycosaminoglycans and autism. It is from the

proceedings of a conference I spoke to in England in 1998. It is still on

the net, and can be read from

there: http://osiris.sunderland.ac.uk/autism/owens.htm. The paper is

copyrighted material and has been published in a book that is for sale

through the Autism Research Unit at the University of Sunderland, so please

everyone, follow copyright laws. Use this for your own reading but do not

use it outside of that.

The " sequel " to that paper from the 2001 Conference in Durham included more

on how GAGs affect neural development and maintenance but that is not on

the net, but can be purchased through the University of Sunderland

But for a list of symptoms that may be attributable to cipro, see:

http://www.gettingwell.com/drug_info/rxdrugprofiles/drugs/CIP1082.shtml

On that page it says:

What side effects may occur?

Side effects cannot be anticipated. If any develop or change in intensity,

inform your doctor as soon as possible. Only your doctor can determine if

it is safe for you to continue taking Cipro.

* Most common side effect:

Nausea

* Less common side effects may include:

Abdominal pain/discomfort, diarrhea, headache, rash, restlessness,

vomiting

* Rare side effects may include:

Abnormal dread or fear, achiness, bleeding in the stomach and/or

intestines, blood clots in the lungs, blurred vision, change in color

perception, chills, confusion, constipation, convulsions, coughing up

blood, decreased vision, depression, difficulty in swallowing, dizziness,

double vision, drowsiness, eye pain, fainting, fever, flushing, gas, gout

flare up, hallucinations, hearing loss, heart attack, hiccups, high blood

pressure, hives, inability to fall or stay asleep, inability to urinate,

indigestion, intestinal inflammation, involuntary eye movement, irregular

heartbeat, irritability, itching, joint or back pain, joint stiffness,

kidney failure, labored breathing, lack of muscle coordination, lack or

loss of appetite, large volumes of urine, light-headedness, loss of sense

of identity, loss of sense of smell, mouth sores, neck pain, nightmares,

nosebleed, pounding heartbeat, ringing in the ears, seizures, sensitivity

to light, severe allergic reaction, skin peeling, redness, sluggishness,

speech difficulties, swelling of the face, neck, lips, eyes, or hands,

swelling of the throat, tender, red bumps on skin, tingling sensation,

tremors, unpleasant taste, unusual darkening of the skin, vaginal

inflammation, vague feeling of illness, weakness, yellowed eyes and skin

AND

Cipro can cause increased pressure within the brain. Convulsions have been

reported in people receiving the drug. If you experience a seizure or

convulsion, notify your doctor immediately.

This medication may stimulate the central nervous system, which may lead to

tremors, restlessness, light-headedness, confusion, depression, and

hallucinations. If these reactions occur, consult your doctor at once.

Other central nervous system reactions include nervousness, agitation,

insomnia, anxiety, nightmares, and paranoia.

If you have a known or suspected central nervous system disorder such as

epilepsy or hardening of the arteries in the brain, make sure your doctor

knows about it when prescribing Cipro.

Remember to stop taking Cipro and see your doctor at the first hint of an

allergic reaction (see " Most important fact about this drug " ). Also call

your doctor if you develop diarrhea. Antibiotics such as Cipro occasionally

trigger a form of diarrhea that needs a doctor's attention.

--------------------------------

Hope this helps.

Am J Sports Med 2000 May-Jun;28(3):364-9 Related Articles, Books, LinkOut

Comment in:

* Am J Sports Med. 2001 Mar-Apr;29(2):262-3.

[Click here to read]

The effect of ciprofloxacin on tendon, paratenon, and capsular

fibroblast metabolism.

RJ III, Attia E, Wickiewicz TL, Hannafin JA.

Laboratory for Soft Tissue Research, Sports Medicine & Shoulder

Service, Hospital for Special Surgery, New York, New York, USA.

....The purpose of this study was to examine the effect of ciprofloxacin on

fibroblast metabolism in vitro.... Ciprofloxacin caused a statistically

significant 36% to 48% decrease in collagen synthesis compared with

controls in all fibroblast cultures. Ciprofloxacin caused a statistically

significant 14% to 60% decrease in proteoglycan synthesis in all fibroblast

cell lines.... The increase in protease activity and the inhibition of both

cell proliferation and the synthesis of matrix ground substance may

contribute to the clinically described tendinopathies associated with

ciprofloxacin therapy.

PMID: 10843129 [PubMed - indexed for MEDLINE]

Hi,

Wondering if someone can help me ASAP. Have a friend who is getting very

sick. Her house was recently treated for mold with some kind of chemical

and she recently took Cipro. Every since she is extremely weak, fatigued,

has tingling in extremities, profuse sweating of the feet, anxiety... .

She was reading that Cipro could have long term side effects simialr to

these but not sure its not an accumualtion of things. Do people have these

symptoms when they are toxic with metals?...I thought they did. My son

also had the profuse feet sweats etc. Wanted thoughts if any of you have

them. Do not have time to do major searches of archives right now...sorry

if this is redundant..