INFO - On methotrexate dosing

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American College of Rheumatology

Patient Education

Rheumatoid Arthritis

Methotrexate

Last updated Jun 2006

Excerpt:

Dosing

Methotrexate comes in 2.5 milligram (mg) tablets. Adults with rheumatoid

arthritis typically begin with a starting dose of 7.5 to 10 mg, or 3 to 4

pills, taken all together once a week. The dose may be increased to 20 to 25

mg a week over time if needed. The medication can be given as an injection

(which comes as 25 mg per 1 milliliter [ml] or cubic centimeter [cc]) under

the skin, like insulin, to reduce side effects or when higher doses are

needed. Adults with other rheumatic conditions may take similar doses. In

children with juvenile arthritis, the dose is based on the patient's weight.

http://www.rheumatology.org/public/factsheets/methotrexate.asp

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