Any Advice greatly appreciated

[Guest guest]

Had my appointment with the rhemy Friday. He uped my predisone to 20mg and my

humira to every week now my worry is the weight gain. The doc. says my RA is out

of control. any Ideas of how to loose weight or how to deal with this disease I

have been on meds since 1990 the doc want to put me on metho as well all the

meds scare me. I am also on pain med but the wants me off them that makes no

sense to me because if it wasn't for the meds I would not be able to work part

time is that is what you'd call it. I am not even able to work 30 hrs a week.

After working I hurt so bad It takes me 4 hrs in the morning to even be able to

dress myself and that is only after I have taken the predisone and celebrex and

a pain pill.

Thanks for listening.

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[Guest guest]

Here's a new a new form of prednisone that helps people get going earlier in

the morning. I don't take it.

Lodotra

Modified-Release Prednisone May Ease Rheumatoid Arthritis THURSDAY, Jan. 17

(HealthDay News) A modified-release form of the steroid prednisone is better

than the standard, immediate-release version at reducing morning joint stiffness

in people with rheumatoid arthritis, a new study finds.

German researchers at Charite University Medicine Berlin studied 288 people

with active rheumatoid arthritis. Half took standard prednisone (a

glucocorticoid) when they woke in the morning and half took modified-release

prednisone at bedtime. The modified-release tablets dispense prednisone four

hours after ingestion.

After 12 weeks of treatment, patients taking the modified-release version

experienced an average of 44 minutes less morning stiffness per day than at the

start of the study. That was 29.2 minutes less than those who took the standard

version, the team noted.

Their report is published in the Jan. 19 issue of The Lancet.

Both versions have nearly identical total drug exposure and maximum

concentration values. They have the same safety profiles.

" Our results have confirmed that the new modified-release formulation is

clinically and statistically better than the conventional immediate-release

preparation with regard to morning stiffness of the joints. Furthermore, the

effects of the new tablet taken at night were achieved in addition to the

established clinical control of the disease resulting from previous treatment

with conventional immediate-release prednisone, " the study authors concluded.

The study was supported by drug maker Merck, which markets the

modified-release form of prednisone under the brand name Lodotra.

-- Preidt

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