Re: Caverject Impulse Injectors unavailable until July 2009

[Guest guest]

You can get it compounded for less money through Pallimed Solutions in Boston, MA. Just call them, they transfer the prescription and mail it right to you. They take insurance and it is a fraction of the cost.

shurben

Caverject Impulse Injectors unavailable until July 2009

If you are currently using the Caverject Impulse Injector System for ED, forget about a new prescription being available until July 2009.According to a representative at Pfizer, the FDA "requested" that the company prepare a better instruction guide for its use. Pfizer also will be making improvements in the injector design during this downtime.In the meantime, Caverject powder will still be sold, although it manually needs to be mixed, and injected with a separate needle.The Impulse syringe is quite a remarkable feat of mechanical engineering. I've uploaded a photo of its parts at:http://health. ph.groups. yahoo.com/ group/ProstateCa ncerSupport/ photos/view/d84c?b= 5Ron

[Guest guest]

When you say a fraction of the cost how much is it and about how many injections do you get? My insurance doesn't pay for it so I am on my own.

Thanks,

Rick

[ProstateCancerSupp ort] Caverject Impulse Injectors unavailable until July 2009

If you are currently using the Caverject Impulse Injector System for ED, forget about a new prescription being available until July 2009.According to a representative at Pfizer, the FDA "requested" that the company prepare a better instruction guide for its use. Pfizer also will be making improvements in the injector design during this downtime.In the meantime, Caverject powder will still be sold, although it manually needs to be mixed, and injected with a separate needle.The Impulse syringe is quite a remarkable feat of mechanical engineering. I've uploaded a photo of its parts at:http://health. ph.groups. yahoo.com/ group/ProstateCa ncerSupport/ photos/view/d84c?b= 5Ron

[Guest guest]

When you say a fraction of the cost how much is it and about how many injections do you get? My insurance doesn't pay for it so I am on my own.

Thanks,

Rick

[ProstateCancerSupp ort] Caverject Impulse Injectors unavailable until July 2009

If you are currently using the Caverject Impulse Injector System for ED, forget about a new prescription being available until July 2009.According to a representative at Pfizer, the FDA "requested" that the company prepare a better instruction guide for its use. Pfizer also will be making improvements in the injector design during this downtime.In the meantime, Caverject powder will still be sold, although it manually needs to be mixed, and injected with a separate needle.The Impulse syringe is quite a remarkable feat of mechanical engineering. I've uploaded a photo of its parts at:http://health. ph.groups. yahoo.com/ group/ProstateCa ncerSupport/ photos/view/d84c?b= 5Ron

[Guest guest]

My insurance covered it and it cost me $45. I get 10 injections in a vial. The pharmacy I was using told me my insurance didn't cover it either, but Pallimed got it covered for me. I know there are some that don't but give Pallimed a call. do not have their phone number right now, but their website is www.pallimed.com

[ProstateCancerSupp ort] Caverject Impulse Injectors unavailable until July 2009

If you are currently using the Caverject Impulse Injector System for ED, forget about a new prescription being available until July 2009.According to a representative at Pfizer, the FDA "requested" that the company prepare a better instruction guide for its use. Pfizer also will be making improvements in the injector design during this downtime.In the meantime, Caverject powder will still be sold, although it manually needs to be mixed, and injected with a separate needle.The Impulse syringe is quite a remarkable feat of mechanical engineering. I've uploaded a photo of its parts at:http://health. ph.groups. yahoo.com/ group/ProstateCa ncerSupport/ photos/view/d84c?b=

5Ron

[Guest guest]

My insurance covered it and it cost me $45. I get 10 injections in a vial. The pharmacy I was using told me my insurance didn't cover it either, but Pallimed got it covered for me. I know there are some that don't but give Pallimed a call. do not have their phone number right now, but their website is www.pallimed.com

[ProstateCancerSupp ort] Caverject Impulse Injectors unavailable until July 2009

If you are currently using the Caverject Impulse Injector System for ED, forget about a new prescription being available until July 2009.According to a representative at Pfizer, the FDA "requested" that the company prepare a better instruction guide for its use. Pfizer also will be making improvements in the injector design during this downtime.In the meantime, Caverject powder will still be sold, although it manually needs to be mixed, and injected with a separate needle.The Impulse syringe is quite a remarkable feat of mechanical engineering. I've uploaded a photo of its parts at:http://health. ph.groups. yahoo.com/ group/ProstateCa ncerSupport/ photos/view/d84c?b=

5Ron

[Guest guest]

Thanks for your information. The telephone number was on your earlier post, I will give them a call when I get my first scrip tomorrow.

Yesterday was my first successful injection with the Caverject Impulse Injector. My uro gave me three sample injectors a couple of months ago(I just got the balls to try it)to see if I liked it. During my first attempt I did everything that the instructions said to do and when I got the needle in the dam injector wouldn't work. So I pulled out the needle and messed around with the injector and still couldn't get it to work. At that point I was to emotionally shot to try it again so we canceled the mission. Yesterday went OK but it was not without incident. Again I got the needle in and it wouldn't inject. So I pulled it out and re-dialed the setting and it worked. So I re-stuck my poor dick and it worked. The results were great, both my wife and I were very pleased with the results. There was very little pain or discomfort and the usable erection lasted about an hour. Things stayed puffy for a couple hours(it looked great) but there was no

discomfort at all. I hope they work on the injector mechanics because as far as I'm concerned it has some issues(not to mention that its to dam expensive). I also think the injector is to big and clunky and doesn't handle as well as a smaller syringe would(not that I ever used one of those either).

Regards,

Rick

[ProstateCancerSupp ort] Caverject Impulse Injectors unavailable until July 2009

If you are currently using the Caverject Impulse Injector System for ED, forget about a new prescription being available until July 2009.According to a representative at Pfizer, the FDA "requested" that the company prepare a better instruction guide for its use. Pfizer also will be making improvements in the injector design during this downtime.In the meantime, Caverject powder will still be sold, although it manually needs to be mixed, and injected with a separate needle.The Impulse syringe is quite a remarkable feat of mechanical engineering. I've uploaded a photo of its parts at:http://health. ph.groups. yahoo.com/ group/ProstateCa ncerSupport/ photos/view/d84c?b=

5Ron

[Guest guest]

Thanks for your information. The telephone number was on your earlier post, I will give them a call when I get my first scrip tomorrow.

Yesterday was my first successful injection with the Caverject Impulse Injector. My uro gave me three sample injectors a couple of months ago(I just got the balls to try it)to see if I liked it. During my first attempt I did everything that the instructions said to do and when I got the needle in the dam injector wouldn't work. So I pulled out the needle and messed around with the injector and still couldn't get it to work. At that point I was to emotionally shot to try it again so we canceled the mission. Yesterday went OK but it was not without incident. Again I got the needle in and it wouldn't inject. So I pulled it out and re-dialed the setting and it worked. So I re-stuck my poor dick and it worked. The results were great, both my wife and I were very pleased with the results. There was very little pain or discomfort and the usable erection lasted about an hour. Things stayed puffy for a couple hours(it looked great) but there was no

discomfort at all. I hope they work on the injector mechanics because as far as I'm concerned it has some issues(not to mention that its to dam expensive). I also think the injector is to big and clunky and doesn't handle as well as a smaller syringe would(not that I ever used one of those either).

Regards,

Rick

[ProstateCancerSupp ort] Caverject Impulse Injectors unavailable until July 2009

If you are currently using the Caverject Impulse Injector System for ED, forget about a new prescription being available until July 2009.According to a representative at Pfizer, the FDA "requested" that the company prepare a better instruction guide for its use. Pfizer also will be making improvements in the injector design during this downtime.In the meantime, Caverject powder will still be sold, although it manually needs to be mixed, and injected with a separate needle.The Impulse syringe is quite a remarkable feat of mechanical engineering. I've uploaded a photo of its parts at:http://health. ph.groups. yahoo.com/ group/ProstateCa ncerSupport/ photos/view/d84c?b=

5Ron

[Guest guest]

Thanks for your information. The telephone number was on your earlier post, I will give them a call when I get my first scrip tomorrow.

Yesterday was my first successful injection with the Caverject Impulse Injector. My uro gave me three sample injectors a couple of months ago(I just got the balls to try it)to see if I liked it. During my first attempt I did everything that the instructions said to do and when I got the needle in the dam injector wouldn't work. So I pulled out the needle and messed around with the injector and still couldn't get it to work. At that point I was to emotionally shot to try it again so we canceled the mission. Yesterday went OK but it was not without incident. Again I got the needle in and it wouldn't inject. So I pulled it out and re-dialed the setting and it worked. So I re-stuck my poor dick and it worked. The results were great, both my wife and I were very pleased with the results. There was very little pain or discomfort and the usable erection lasted about an hour. Things stayed puffy for a couple hours(it looked great) but there was no

discomfort at all. I hope they work on the injector mechanics because as far as I'm concerned it has some issues(not to mention that its to dam expensive). I also think the injector is to big and clunky and doesn't handle as well as a smaller syringe would(not that I ever used one of those either).

Regards,

Rick

[ProstateCancerSupp ort] Caverject Impulse Injectors unavailable until July 2009

If you are currently using the Caverject Impulse Injector System for ED, forget about a new prescription being available until July 2009.According to a representative at Pfizer, the FDA "requested" that the company prepare a better instruction guide for its use. Pfizer also will be making improvements in the injector design during this downtime.In the meantime, Caverject powder will still be sold, although it manually needs to be mixed, and injected with a separate needle.The Impulse syringe is quite a remarkable feat of mechanical engineering. I've uploaded a photo of its parts at:http://health. ph.groups. yahoo.com/ group/ProstateCa ncerSupport/ photos/view/d84c?b=

5Ron

[Guest guest]

I remember my first injection. After two years I cried when we were done. Enjoy

Subject: Re: Caverject Impulse Injectors unavailable until July 2009To: ProstateCancerSupport Date: Tuesday, September 2, 2008, 11:20 AM

Thanks for your information. The telephone number was on your earlier post, I will give them a call when I get my first scrip tomorrow.

Yesterday was my first successful injection with the Caverject Impulse Injector. My uro gave me three sample injectors a couple of months ago(I just got the balls to try it)to see if I liked it. During my first attempt I did everything that the instructions said to do and when I got the needle in the dam injector wouldn't work. So I pulled out the needle and messed around with the injector and still couldn't get it to work. At that point I was to emotionally shot to try it again so we canceled the mission. Yesterday went OK but it was not without incident. Again I got the needle in and it wouldn't inject. So I pulled it out and re-dialed the setting and it worked. So I re-stuck my poor dick and it worked. The results were great, both my wife and I were very pleased with the results. There was very little pain or discomfort and the usable erection lasted about an hour. Things stayed puffy for a couple hours(it looked great) but there was no

discomfort at all. I hope they work on the injector mechanics because as far as I'm concerned it has some issues(not to mention that its to dam expensive). I also think the injector is to big and clunky and doesn't handle as well as a smaller syringe would(not that I ever used one of those either).

Regards,

Rick

[ProstateCancerSupp ort] Caverject Impulse Injectors unavailable until July 2009

If you are currently using the Caverject Impulse Injector System for ED, forget about a new prescription being available until July 2009.According to a representative at Pfizer, the FDA "requested" that the company prepare a better instruction guide for its use. Pfizer also will be making improvements in the injector design during this downtime.In the meantime, Caverject powder will still be sold, although it manually needs to be mixed, and injected with a separate needle.The Impulse syringe is quite a remarkable feat of mechanical engineering. I've uploaded a photo of its parts at:http://health. ph.groups. yahoo.com/ group/ProstateCa ncerSupport/ photos/view/d84c?b=

5Ron

[Guest guest]

I remember my first injection. After two years I cried when we were done. Enjoy

Subject: Re: Caverject Impulse Injectors unavailable until July 2009To: ProstateCancerSupport Date: Tuesday, September 2, 2008, 11:20 AM

Thanks for your information. The telephone number was on your earlier post, I will give them a call when I get my first scrip tomorrow.

Yesterday was my first successful injection with the Caverject Impulse Injector. My uro gave me three sample injectors a couple of months ago(I just got the balls to try it)to see if I liked it. During my first attempt I did everything that the instructions said to do and when I got the needle in the dam injector wouldn't work. So I pulled out the needle and messed around with the injector and still couldn't get it to work. At that point I was to emotionally shot to try it again so we canceled the mission. Yesterday went OK but it was not without incident. Again I got the needle in and it wouldn't inject. So I pulled it out and re-dialed the setting and it worked. So I re-stuck my poor dick and it worked. The results were great, both my wife and I were very pleased with the results. There was very little pain or discomfort and the usable erection lasted about an hour. Things stayed puffy for a couple hours(it looked great) but there was no

discomfort at all. I hope they work on the injector mechanics because as far as I'm concerned it has some issues(not to mention that its to dam expensive). I also think the injector is to big and clunky and doesn't handle as well as a smaller syringe would(not that I ever used one of those either).

Regards,

Rick

[ProstateCancerSupp ort] Caverject Impulse Injectors unavailable until July 2009

If you are currently using the Caverject Impulse Injector System for ED, forget about a new prescription being available until July 2009.According to a representative at Pfizer, the FDA "requested" that the company prepare a better instruction guide for its use. Pfizer also will be making improvements in the injector design during this downtime.In the meantime, Caverject powder will still be sold, although it manually needs to be mixed, and injected with a separate needle.The Impulse syringe is quite a remarkable feat of mechanical engineering. I've uploaded a photo of its parts at:http://health. ph.groups. yahoo.com/ group/ProstateCa ncerSupport/ photos/view/d84c?b=

5Ron

[Guest guest]

As the late Red Buttons used to say, " Strange things are happening...

Strange things... "

In 1995 the FDA approved the sale of Upjohn's Caverject, an injectable

from of prostaglandin E1, which became the first prescription drug for

treating impotence.

Recently, Pharmacia & Upjohn sold Caverject to Pfizer. Pfizer has now

, in effect, taken the Caverject Impulse off the market. My urologist

also told me that he is having problems finding a source for the

powdered version of Caverject. Why is this happening? You remember

Pfizer...the people who brought you Viagra? Are they trying to

eliminate the competition? I really don't know, but it does seem a

little strange.

Also, our wonderful healthcare system (NOT!) seems to be really in a

fog over pricing and co-pays. My plan covers Caverject Impulse and

powder under their highest co-pay. Bi-Mix and Tri-Mix are not covered

at all. They must be prepared by a compounding pharmacy.

I have a call into the FDA to see what they make of all this. I'll

let the group know if and when I hear from them.

Ron

>

> My insurance covered it and it cost me $45.  I get 10 injections in

a vial.  The pharmacy I was using told me my insurance didn't cover it

either, but Pallimed got it covered for me.  I know there are some

that don't but give Pallimed a call.   do not have their phone number

right now, but their website is www.pallimed.com

>  

>

[Guest guest]

Ron,

Got a couple of Caverject Impulse Injectors samples to try out a few months ago. Tried them and had great results. I went back to the uro today to get results of my fourth PSA since my RP(still undetectable, YEA!) and to get a script for more of the Caverject. I kinda knew that it was off the market and I was hoping that he would give me a script for a generic brand but he gave me one for Edex. Do you or does anyone out there have any experience with Edex? Does it work the same and how much does it cost? I am going to do some research and find out what I can about it but this is for sure the best place to start.

Regards,

Rick

Re: Caverject Impulse Injectors unavailable until July 2009

As the late Red Buttons used to say, "Strange things are happening... Strange things..."In 1995 the FDA approved the sale of Upjohn's Caverject, an injectable from of prostaglandin E1, which became the first prescription drug for treating impotence.Recently, Pharmacia & Upjohn sold Caverject to Pfizer. Pfizer has now , in effect, taken the Caverject Impulse off the market. My urologist also told me that he is having problems finding a source for the powdered version of Caverject. Why is this happening? You remember Pfizer...the people who brought you Viagra? Are they trying to eliminate the competition? I really don't know, but it does seem a little strange.Also, our wonderful healthcare system (NOT!) seems to be really in a fog over pricing and co-pays. My plan covers Caverject Impulse and powder under their highest co-pay. Bi-Mix and Tri-Mix are not covered at all. They must

be prepared by a compounding pharmacy.I have a call into the FDA to see what they make of all this. I'll let the group know if and when I hear from them.Ron>> My insurance covered it and it cost me $45. I get 10 injections in a vial. The pharmacy I was using told me my insurance didn't cover it either, but Pallimed got it covered for me. I know there are some that don't but give Pallimed a call. do not have their phone number right now, but their website is www.pallimed. com> >

[Guest guest]

Rick:I use the Edex. Same reason, generic version of the caverject. Works well. Like everything else, you have to titrate the dose. I get the 2-pack of 10 mcg syringes of the Edex. I measure out 1.5-2.0 mcg into an insulin syringe, and use this as my dose. I get 5-6 injections per syringe that way. Some discomfort from the alprostadil, but if I use less than 2 mcg it is minimal. Works well, gives me an erection that lasts between 1 and 2 hours. Because it is generic, my insurance plan covers it for the $10 copay. So it comes out to about $1 per dose, plus the cost of the insulin syringe, alcohol wipes, etc. Alot of people use the trimix, with success. I've done well with the edex, so I haven't gone to the trimix, which must be compounded. Also, remember to refrigerate the edex, the alprostadil loses activity if left at room temp.Best of luck, To: ProstateCancerSupport From: white.richard54@...Date: Wed, 3 Sep 2008 18:44:32 -0700Subject: Re: Re: Caverject Impulse Injectors unavailable until July 2009

Ron,

Got a couple of Caverject Impulse Injectors samples to try out a few months ago. Tried them and had great results. I went back to the uro today to get results of my fourth PSA since my RP(still undetectable, YEA!) and to get a script for more of the Caverject. I kinda knew that it was off the market and I was hoping that he would give me a script for a generic brand but he gave me one for Edex. Do you or does anyone out there have any experience with Edex? Does it work the same and how much does it cost? I am going to do some research and find out what I can about it but this is for sure the best place to start.

Regards,

Rick

Re: Caverject Impulse Injectors unavailable until July 2009

As the late Red Buttons used to say, "Strange things are happening... Strange things..."In 1995 the FDA approved the sale of Upjohn's Caverject, an injectable from of prostaglandin E1, which became the first prescription drug for treating impotence.Recently, Pharmacia & Upjohn sold Caverject to Pfizer. Pfizer has now , in effect, taken the Caverject Impulse off the market. My urologist also told me that he is having problems finding a source for the powdered version of Caverject. Why is this happening? You remember Pfizer...the people who brought you Viagra? Are they trying to eliminate the competition? I really don't know, but it does seem a little strange.Also, our wonderful healthcare system (NOT!) seems to be really in a fog over pricing and co-pays. My plan covers Caverject Impulse and powder under their highest co-pay. Bi-Mix and Tri-Mix are not covered at all. They must

be prepared by a compounding pharmacy.I have a call into the FDA to see what they make of all this. I'll let the group know if and when I hear from them.Ron>> My insurance covered it and it cost me $45. I get 10 injections in a vial. The pharmacy I was using told me my insurance didn't cover it either, but Pallimed got it covered for me. I know there are some that don't but give Pallimed a call. do not have their phone number right now, but their website is www.pallimed. com> >

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[Guest guest]

Not a lot of info on the Internet about Edex. It IS FDA approved.

It is manufactured by Schwarz Pharma in Germany

http://www.schwarzpharma.com/sp/n49/Products/

Schwarz Pharma is a subsidery of UCB

http://www.ucb-group.com/products/product_list/other/834.asp

The description of the injector sounds interesting, and similar to

Caverject, although I couldn't find a photo.

http://www.rxlist.com/cgi/generic/edex.htm

How available is this stuff in the U.S.?

Ron K

-- In ProstateCancerSupport , White

wrote:

Do you or does anyone out there have any experience with Edex? Does it

work the same and how much does it cost? I am going to do some

research and find out what I can about it but this is for sure the

best place to start.

> Regards,

> Rick

>

[Guest guest]

Not a lot of info on the Internet about Edex. It IS FDA approved.

It is manufactured by Schwarz Pharma in Germany

http://www.schwarzpharma.com/sp/n49/Products/

Schwarz Pharma is a subsidery of UCB

http://www.ucb-group.com/products/product_list/other/834.asp

The description of the injector sounds interesting, and similar to

Caverject, although I couldn't find a photo.

http://www.rxlist.com/cgi/generic/edex.htm

How available is this stuff in the U.S.?

Ron K

-- In ProstateCancerSupport , White

wrote:

Do you or does anyone out there have any experience with Edex? Does it

work the same and how much does it cost? I am going to do some

research and find out what I can about it but this is for sure the

best place to start.

> Regards,

> Rick

>

[Guest guest]

Not a lot of info on the Internet about Edex. It IS FDA approved.

It is manufactured by Schwarz Pharma in Germany

http://www.schwarzpharma.com/sp/n49/Products/

Schwarz Pharma is a subsidery of UCB

http://www.ucb-group.com/products/product_list/other/834.asp

The description of the injector sounds interesting, and similar to

Caverject, although I couldn't find a photo.

http://www.rxlist.com/cgi/generic/edex.htm

How available is this stuff in the U.S.?

Ron K

-- In ProstateCancerSupport , White

wrote:

Do you or does anyone out there have any experience with Edex? Does it

work the same and how much does it cost? I am going to do some

research and find out what I can about it but this is for sure the

best place to start.

> Regards,

> Rick

>

[Guest guest]

Seems that every time you talk to a different source about the same thing you get a different instructions. My dr gave me 3, 20mcg sample Caverjet syringes and told me to set it for 20mcg and only inject 1/2 and wipe off the needle and keep it in the fridge for the next time. Now the instruction pamphlet reads nothing like that.

In my research on the Edex one of the guys on the site put me onto www.pallimed.com and if you go on their site they offer four injectables, PGE1, Bi-Mix, Tri-Mix and one I never heard of Quad-Mix. In their instructions they say that all the injectables except Bi-Mix needs to be refrigerated. Who do you believe?

Re: Caverject Impulse Injectors unavailable until July 2009

I received the following note from the FDA:"Thank you for writing the Division of Drug Information, in the FDA'sCenter for Drug Evaluation and Research.Only the sponsor would be able to release information concerningmanufacturing or regulatory issues since it is considered proprietary.The FDA would not be able to post this information on our site.Best regards,CAODivision of Drug InformationCenter for Drug Evaluation and ResearchFood and Drug Administration"____________ _________ _________ _________ _______Gee! And I thought the FDA worked for us! :-)The latest information on the Caverject Impulse can be heard on a recording from Pfiser at 1-.FYI, Pfizer acquired Pharmica Up who produced Caverject powder and the Impulse. The powder is still available, but- TALK ABOUT CONVOLUTED INSTRUCTIONS! WOW! :-)By the way, contrary to other alprostadil

storage instructions, Pfizer says that neither the powder, nor the diluted mixture should be stored in the refrigerator. Keep the mixture at room temperature and disguard after 24 hours.The fun continues...

[Guest guest]

Seems that every time you talk to a different source about the same thing you get a different instructions. My dr gave me 3, 20mcg sample Caverjet syringes and told me to set it for 20mcg and only inject 1/2 and wipe off the needle and keep it in the fridge for the next time. Now the instruction pamphlet reads nothing like that.

In my research on the Edex one of the guys on the site put me onto www.pallimed.com and if you go on their site they offer four injectables, PGE1, Bi-Mix, Tri-Mix and one I never heard of Quad-Mix. In their instructions they say that all the injectables except Bi-Mix needs to be refrigerated. Who do you believe?

Re: Caverject Impulse Injectors unavailable until July 2009

I received the following note from the FDA:"Thank you for writing the Division of Drug Information, in the FDA'sCenter for Drug Evaluation and Research.Only the sponsor would be able to release information concerningmanufacturing or regulatory issues since it is considered proprietary.The FDA would not be able to post this information on our site.Best regards,CAODivision of Drug InformationCenter for Drug Evaluation and ResearchFood and Drug Administration"____________ _________ _________ _________ _______Gee! And I thought the FDA worked for us! :-)The latest information on the Caverject Impulse can be heard on a recording from Pfiser at 1-.FYI, Pfizer acquired Pharmica Up who produced Caverject powder and the Impulse. The powder is still available, but- TALK ABOUT CONVOLUTED INSTRUCTIONS! WOW! :-)By the way, contrary to other alprostadil

storage instructions, Pfizer says that neither the powder, nor the diluted mixture should be stored in the refrigerator. Keep the mixture at room temperature and disguard after 24 hours.The fun continues...

[Guest guest]

Hi Rich:I refrigerate my Edex. I also use the needle again. After the 2nd dose (I get more than two out of my 10 mcg syringe), I inject it into an insulin syringe and use a fresh needle-it is less painful to stick. To: ProstateCancerSupport From: white.richard54@...Date: Mon, 8 Sep 2008 11:20:33 -0700Subject: Re: Re: Caverject Impulse Injectors unavailable until July 2009

Seems that every time you talk to a different source about the same thing you get a different instructions. My dr gave me 3, 20mcg sample Caverjet syringes and told me to set it for 20mcg and only inject 1/2 and wipe off the needle and keep it in the fridge for the next time. Now the instruction pamphlet reads nothing like that.

In my research on the Edex one of the guys on the site put me onto www.pallimed.com and if you go on their site they offer four injectables, PGE1, Bi-Mix, Tri-Mix and one I never heard of Quad-Mix. In their instructions they say that all the injectables except Bi-Mix needs to be refrigerated. Who do you believe?

Re: Caverject Impulse Injectors unavailable until July 2009

I received the following note from the FDA:"Thank you for writing the Division of Drug Information, in the FDA'sCenter for Drug Evaluation and Research.Only the sponsor would be able to release information concerningmanufacturing or regulatory issues since it is considered proprietary.The FDA would not be able to post this information on our site.Best regards,CAODivision of Drug InformationCenter for Drug Evaluation and ResearchFood and Drug Administration"____________ _________ _________ _________ _______Gee! And I thought the FDA worked for us! :-)The latest information on the Caverject Impulse can be heard on a recording from Pfiser at 1-.FYI, Pfizer acquired Pharmica Up who produced Caverject powder and the Impulse. The powder is still available, but- TALK ABOUT CONVOLUTED INSTRUCTIONS! WOW! :-)By the way, contrary to other alprostadil

storage instructions, Pfizer says that neither the powder, nor the diluted mixture should be stored in the refrigerator. Keep the mixture at room temperature and disguard after 24 hours.The fun continues...

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[Guest guest]

Hi Rich:I refrigerate my Edex. I also use the needle again. After the 2nd dose (I get more than two out of my 10 mcg syringe), I inject it into an insulin syringe and use a fresh needle-it is less painful to stick. To: ProstateCancerSupport From: white.richard54@...Date: Mon, 8 Sep 2008 11:20:33 -0700Subject: Re: Re: Caverject Impulse Injectors unavailable until July 2009

Seems that every time you talk to a different source about the same thing you get a different instructions. My dr gave me 3, 20mcg sample Caverjet syringes and told me to set it for 20mcg and only inject 1/2 and wipe off the needle and keep it in the fridge for the next time. Now the instruction pamphlet reads nothing like that.

In my research on the Edex one of the guys on the site put me onto www.pallimed.com and if you go on their site they offer four injectables, PGE1, Bi-Mix, Tri-Mix and one I never heard of Quad-Mix. In their instructions they say that all the injectables except Bi-Mix needs to be refrigerated. Who do you believe?

Re: Caverject Impulse Injectors unavailable until July 2009

I received the following note from the FDA:"Thank you for writing the Division of Drug Information, in the FDA'sCenter for Drug Evaluation and Research.Only the sponsor would be able to release information concerningmanufacturing or regulatory issues since it is considered proprietary.The FDA would not be able to post this information on our site.Best regards,CAODivision of Drug InformationCenter for Drug Evaluation and ResearchFood and Drug Administration"____________ _________ _________ _________ _______Gee! And I thought the FDA worked for us! :-)The latest information on the Caverject Impulse can be heard on a recording from Pfiser at 1-.FYI, Pfizer acquired Pharmica Up who produced Caverject powder and the Impulse. The powder is still available, but- TALK ABOUT CONVOLUTED INSTRUCTIONS! WOW! :-)By the way, contrary to other alprostadil

storage instructions, Pfizer says that neither the powder, nor the diluted mixture should be stored in the refrigerator. Keep the mixture at room temperature and disguard after 24 hours.The fun continues...

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[Guest guest]

I spoke to Jim Nahill who owns Pallimed Pharmacy Solutions who makes my trimix and he explained that these preparations are going to be made differently from one pharmacy to the next. The important thing is that you get a consistant product. because the amount needed to have the same erection can be different from one batch to the next. The reason my doctor sent me to pallimed is becasue they sat down with my doctor and showed them exactly how they make it, so that both the doctor and the pharmacy were on the same page and my doctor new what to expect. I told him why I was asking and about this group, and he told me that if anyone in this group is considering using his mixes, he will give you a free vial with a

prescription, so you can try it before you buy it. They are really open for discussions there and The Brigham & Women's hospital thinks very highly of them. His number is , he said he can ship anywhere. I did not ask about the cost of shipping.

All mixes need to be refrigerated except bimix, because the phentolamine and papaverine are stable at room temperature for 30 days, and, depending on how the pharmacy makes the preparation, may also have preservatives to prevent bacterial growth.

I also asked how important the refrigeration was. They said that refrigeration is important for all mixes including bimix, once the vial has been entered in a non sterile area....which is basically anywhere outside a cleanroom. BUT, he also said thet the refrigeration issue is a little overblown because even if you left tri-mix out over night you might only lose 1-2 % of the drug. He gave me a lot of mumbo0jumbo about some regulatory guidelines he needs to follow for this stuff, and I did not really understand everything he was saying, but they have been incredibly upfront with me, so i trust them.

Sherland

PS Quad-mix has atropine in it, and they do not suggest it...he said it is a gimick that the Boston Medical Group uses...it doesn't help. The only reason he has it is for guys who want to use his pharmacy but want the same thing they got at the Boston Group.

[ProstateCancerSupp ort] Re: Caverject Impulse Injectors unavailable until July 2009

I received the following note from the FDA:"Thank you for writing the Division of Drug Information, in the FDA'sCenter for Drug Evaluation and Research.Only the sponsor would be able to release information concerningmanufacturing or regulatory issues since it is considered proprietary.The FDA would not be able to post this information on our site.Best regards,CAODivision of Drug InformationCenter for Drug Evaluation and ResearchFood and Drug Administration"____________ _________ _________ _________ _______Gee! And I thought the FDA worked for us! :-)The latest information on the Caverject Impulse can be heard on a recording from Pfiser at 1-.FYI, Pfizer acquired Pharmica Up who produced Caverject powder and the Impulse. The powder is still available, but- TALK ABOUT CONVOLUTED INSTRUCTIONS! WOW! :-)By the way, contrary to other alprostadil

storage instructions, Pfizer says that neither the powder, nor the diluted mixture should be stored in the refrigerator. Keep the mixture at room temperature and disguard after 24 hours.The fun continues...

[Guest guest]

I spoke to Jim Nahill who owns Pallimed Pharmacy Solutions who makes my trimix and he explained that these preparations are going to be made differently from one pharmacy to the next. The important thing is that you get a consistant product. because the amount needed to have the same erection can be different from one batch to the next. The reason my doctor sent me to pallimed is becasue they sat down with my doctor and showed them exactly how they make it, so that both the doctor and the pharmacy were on the same page and my doctor new what to expect. I told him why I was asking and about this group, and he told me that if anyone in this group is considering using his mixes, he will give you a free vial with a

prescription, so you can try it before you buy it. They are really open for discussions there and The Brigham & Women's hospital thinks very highly of them. His number is , he said he can ship anywhere. I did not ask about the cost of shipping.

All mixes need to be refrigerated except bimix, because the phentolamine and papaverine are stable at room temperature for 30 days, and, depending on how the pharmacy makes the preparation, may also have preservatives to prevent bacterial growth.

I also asked how important the refrigeration was. They said that refrigeration is important for all mixes including bimix, once the vial has been entered in a non sterile area....which is basically anywhere outside a cleanroom. BUT, he also said thet the refrigeration issue is a little overblown because even if you left tri-mix out over night you might only lose 1-2 % of the drug. He gave me a lot of mumbo0jumbo about some regulatory guidelines he needs to follow for this stuff, and I did not really understand everything he was saying, but they have been incredibly upfront with me, so i trust them.

Sherland

PS Quad-mix has atropine in it, and they do not suggest it...he said it is a gimick that the Boston Medical Group uses...it doesn't help. The only reason he has it is for guys who want to use his pharmacy but want the same thing they got at the Boston Group.

[ProstateCancerSupp ort] Re: Caverject Impulse Injectors unavailable until July 2009

I received the following note from the FDA:"Thank you for writing the Division of Drug Information, in the FDA'sCenter for Drug Evaluation and Research.Only the sponsor would be able to release information concerningmanufacturing or regulatory issues since it is considered proprietary.The FDA would not be able to post this information on our site.Best regards,CAODivision of Drug InformationCenter for Drug Evaluation and ResearchFood and Drug Administration"____________ _________ _________ _________ _______Gee! And I thought the FDA worked for us! :-)The latest information on the Caverject Impulse can be heard on a recording from Pfiser at 1-.FYI, Pfizer acquired Pharmica Up who produced Caverject powder and the Impulse. The powder is still available, but- TALK ABOUT CONVOLUTED INSTRUCTIONS! WOW! :-)By the way, contrary to other alprostadil

storage instructions, Pfizer says that neither the powder, nor the diluted mixture should be stored in the refrigerator. Keep the mixture at room temperature and disguard after 24 hours.The fun continues...

[Guest guest]

I spoke to Jim Nahill who owns Pallimed Pharmacy Solutions who makes my trimix and he explained that these preparations are going to be made differently from one pharmacy to the next. The important thing is that you get a consistant product. because the amount needed to have the same erection can be different from one batch to the next. The reason my doctor sent me to pallimed is becasue they sat down with my doctor and showed them exactly how they make it, so that both the doctor and the pharmacy were on the same page and my doctor new what to expect. I told him why I was asking and about this group, and he told me that if anyone in this group is considering using his mixes, he will give you a free vial with a

prescription, so you can try it before you buy it. They are really open for discussions there and The Brigham & Women's hospital thinks very highly of them. His number is , he said he can ship anywhere. I did not ask about the cost of shipping.

All mixes need to be refrigerated except bimix, because the phentolamine and papaverine are stable at room temperature for 30 days, and, depending on how the pharmacy makes the preparation, may also have preservatives to prevent bacterial growth.

I also asked how important the refrigeration was. They said that refrigeration is important for all mixes including bimix, once the vial has been entered in a non sterile area....which is basically anywhere outside a cleanroom. BUT, he also said thet the refrigeration issue is a little overblown because even if you left tri-mix out over night you might only lose 1-2 % of the drug. He gave me a lot of mumbo0jumbo about some regulatory guidelines he needs to follow for this stuff, and I did not really understand everything he was saying, but they have been incredibly upfront with me, so i trust them.

Sherland

PS Quad-mix has atropine in it, and they do not suggest it...he said it is a gimick that the Boston Medical Group uses...it doesn't help. The only reason he has it is for guys who want to use his pharmacy but want the same thing they got at the Boston Group.

[ProstateCancerSupp ort] Re: Caverject Impulse Injectors unavailable until July 2009

I received the following note from the FDA:"Thank you for writing the Division of Drug Information, in the FDA'sCenter for Drug Evaluation and Research.Only the sponsor would be able to release information concerningmanufacturing or regulatory issues since it is considered proprietary.The FDA would not be able to post this information on our site.Best regards,CAODivision of Drug InformationCenter for Drug Evaluation and ResearchFood and Drug Administration"____________ _________ _________ _________ _______Gee! And I thought the FDA worked for us! :-)The latest information on the Caverject Impulse can be heard on a recording from Pfiser at 1-.FYI, Pfizer acquired Pharmica Up who produced Caverject powder and the Impulse. The powder is still available, but- TALK ABOUT CONVOLUTED INSTRUCTIONS! WOW! :-)By the way, contrary to other alprostadil

storage instructions, Pfizer says that neither the powder, nor the diluted mixture should be stored in the refrigerator. Keep the mixture at room temperature and disguard after 24 hours.The fun continues...

[Guest guest]

Liam,

Well I ordered my first prescription from Pallimed yesterday. When I faxed my script Jim called me back personally. What a great guy to deal with! We spoke for probably close to a half hour and he explained all about how to draw the needle(Caverject was what I got from my Dr so I didn't have to do the needle thing) and how and what to do during injection and after wards. He also went over how its made, shelf life, storage and everything. He also asked me to call him and let him know how it went and he would help me with and issues that I may have. I feel much better about the whole process after talking to him. And,the first 5cc.vial was free! I would highly recommend Pallimed to anyone, and not because of the free vial but because of the way he dealt with me personally.

I can hardly wait for the mailman to get here.

Thanks for the information,

Rick

[ProstateCancerSupp ort] Re: Caverject Impulse Injectors unavailable until July 2009

I received the following note from the FDA:"Thank you for writing the Division of Drug Information, in the FDA'sCenter for Drug Evaluation and Research.Only the sponsor would be able to release information concerningmanufacturing or regulatory issues since it is considered proprietary.The FDA would not be able to post this information on our site.Best regards,CAODivision of Drug InformationCenter for Drug Evaluation and ResearchFood and Drug Administration"____________ _________ _________ _________ _______Gee! And I thought the FDA worked for us! :-)The latest information on the Caverject Impulse can be heard on a recording from Pfiser at 1-.FYI, Pfizer acquired Pharmica Up who produced Caverject powder and the Impulse. The powder is still available, but- TALK ABOUT CONVOLUTED INSTRUCTIONS! WOW! :-)By the way, contrary to other alprostadil

storage instructions, Pfizer says that neither the powder, nor the diluted mixture should be stored in the refrigerator. Keep the mixture at room temperature and disguard after 24 hours.The fun continues...