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I was first diagnosed with PCa in June 2006 with a PSA of 11.2.

Since that time I have been doing AS or WW. I changed my diet and was

very much attuned to being healthy and eating better. From June 2006

until Jan 2008 my PSA had decreased and held steady at about 8.7 and

very often was as low as 8. Last April things changed and it rose to

12.3, the highest it had been to that date. I just had another PSA

last week and it came in at 16.6.

All the previous tests were done at Quest Diagnostics (Bayer

Chemiluminescent Methodology), the latest at LabCorp ( Roche ECLIA

methodology). I know different methodology should not be compared and

apparently these are different methods.

My question is this...if the methods cannot be compared is one more

valid than the other. And, if the methods vary so much then why do we

have a cutoff of 2.5, or 4, or whatever to indicate a biopsy or

further investigation? Just curious.

In any event, my own PSADT is now 11.6 months, which is a radical

change from a year ago when it was actually a negative number. I am

in a divorce and trying to keep a business alive in these iffy times.

I do have stress but not an overpowering amount by any means. So, my

other questioon is this...could these things effect PSA? I know not

to ejaculate, ride bikes, horses etc for 72 hours before a PSA test so

these things do not factor in.

Any ideas or comments?

Jeff

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