REVIEW - Factors that may mediate the relationship between physical activity and the risk for developing knee OA

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Arthritis Research & Therapy 2008, 10:203doi:10.1186/ar2343

Published: 4 February 2008

Review

Factors that may mediate the relationship between physical activity

and the risk for developing knee osteoarthritis

Donna M Urquhart1 , Soufan1 , J Teichtahl1 , Anita E

Wluka1,2 , Fahad Hanna1 and Flavia M Cicuttini1

1Department of Epidemiology and Preventive Medicine, Monash

University, Alfred Hospital, Commercial Road, Melbourne 3004,

Australia

2Baker Heart Research Institute, AMREP Centre, Commercial Road,

Melbourne, 3004, Australia

Abstract

Studies investigating the effect of physical activity on risk for

developing osteoarthritis at weight-bearing joints have reported

conflicting results. We examine evidence to suggest that this may be

due to the existence of subgroups of individuals who differ in their

response to physical activity, as well as methodological issues

associated with the assessment of knee joint structure and physical

activity. Recommendations for future studies of physical activity and

the development of knee osteoarthritis are discussed.

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Read the full article here:

http://arthritis-research.com/content/10/1/203

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