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I am new to the group and just got diagnosed by one doctor and not by

another. My antinuclear antibodies were 1:160. I have severe

degeneration in the lumbar/sacral at L5 S1 and L4 and L5 and I have

intractable pain in that area. I don't know who to believe. I was

offered a small dose of prednisone or methotrexate. Prednisone does

something to my central nervous system and I don't know anything about

methotrexate. Does it have the same effect? I took 7.5 mgs. today and I

am worried I may not need it. I am so confused. Meg

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