25% of Gleason Scores Are Upgraded After R.P. Tissue Exam

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In general, prostate biopsy Gleason scores are upgraded in RP specimens

in approximately 25% of cases. Mayo Clinic researchers investigated the impact of

the Gleason score discordance on biochemical recurrence (BCR), systemic

progression, and death from CaP. They also evaluated the additional

prognostic value of incorporating biopsy Gleason score into the scoring

algorithm incorporating Gleason score, PSA, and seminal vesicle and

surgical margin status (GPSM).

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