CASE REPORT - Osteonecrosis and monoarticular RA treated with intra-articular Humira

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Mod Rheumatol. 2008 Feb 20 [Epub ahead of print]

Osteonecrosis and monoarticular rheumatoid arthritis treated with

intra-articular adalimumab.

Kobak S.

Department of Rheumatology, Manisa Hospital, Manisa, Turkey,

senolkobak@....

We report a 54-year-old patient with RA presented with osteonecrosis

(ON) and monoarthritis of left knee remitting in the last 2 years.

Monoarthritis was resistant to disease-modifying antirheumatic drugs

(DMARDs) and intra-articular corticosteroids. Intra-articular

administration of adalimumab provided a good clinical and radiographic

response. Synovitis resolved and osteonecrosis disappeared almost

totally.

PMID: 18286352

http://www.ncbi.nlm.nih.gov/pubmed/18286352

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Not an MD