Guest guest Posted March 23, 2008 Report Share Posted March 23, 2008 It's probably the methorexate I have been upped to 8 of them a week and I have had a lot of nausea but too it could be the combination of med's that she takes. In a message dated 3/23/2008 6:07:34 A.M. Mountain Daylight Time, seriouslysanibel@... writes: It is really hard to say what is causing her nausea as it could be any one or a combination of any of those medications. She is on so many pills it could be causing stomach upset or it could be the side effect of the medication themselves. Given my experience I would suspect methotrexate or the Celebrex before the plaquenil, but the doctor pulled it probably because it is usually the least effective of the three. I just started methotrexate again and it has diminished my appetite nicely throughout the week. It was better than the last time I tried and was just plain nauseated and sick for 4 - 5 days. Remember that MTX is quite the toxic drug, they use it to induce abortions and to treat a variety of cancers (in higher doses) such as lymphoma. So yes, it can cause nausea. It is nice to hear she does not have joint damage but as you said, it has only been six months. Unfortunately, she will get there at some time and at some degree. Hopefully her RA isn't extremely aggressive and she can lead a full and active life. Shandi willowspirit26 <_willowspirit26@willowspi_ (mailto:willowspirit26@...) > wrote: Hi All- My daughter has RA and was on Methatraxate, Plaquinil(sp)My daughter Folic acid supps and several pain meds and a sleeping pill, when needed. She has developed constant nausea that has lasted for the past two weeks +. Has anyone had that reaction to any of the above meds? Her rheumy took her off the Placquinil on Thursday and said taking her off the Methatraxate would be next if this didn't help in two weeks. So far it hasn't helped much at all. She has been able to eat a couple meals without feeling ill after several bites since Thursday but the nausea is still dominating her life. Just wondering if anyone else had dealt with this problem. On the plus side, her inflammation has deminished by over 50% since she was diagnosed about 6 months ago and she has never had any joint damage. Thanks, Vicki --------------------------------- Looking for last minute shopping deals? Find them fast with Search. [Non-text portions of this message have been removed] **************Create a Home Theater Like the Pros. Watch the video on AOL Home. (http://home.aol.com/diy/home-improvement-eric-stromer?video=15?ncid=aolhom00030\ 000000001) Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 23, 2008 Report Share Posted March 23, 2008 It is really hard to say what is causing her nausea as it could be any one or a combination of any of those medications. She is on so many pills it could be causing stomach upset or it could be the side effect of the medication themselves. Given my experience I would suspect methotrexate or the Celebrex before the plaquenil, but the doctor pulled it probably because it is usually the least effective of the three. I just started methotrexate again and it has diminished my appetite nicely throughout the week. It was better than the last time I tried and was just plain nauseated and sick for 4 - 5 days. Remember that MTX is quite the toxic drug, they use it to induce abortions and to treat a variety of cancers (in higher doses) such as lymphoma. So yes, it can cause nausea. It is nice to hear she does not have joint damage but as you said, it has only been six months. Unfortunately, she will get there at some time and at some degree. Hopefully her RA isn't extremely aggressive and she can lead a full and active life. Shandi willowspirit26 <willowspirit26@...> wrote: Hi All- My daughter has RA and was on Methatraxate, Plaquinil(sp), Celebrex, Folic acid supps and several pain meds and a sleeping pill, when needed. She has developed constant nausea that has lasted for the past two weeks +. Has anyone had that reaction to any of the above meds? Her rheumy took her off the Placquinil on Thursday and said taking her off the Methatraxate would be next if this didn't help in two weeks. So far it hasn't helped much at all. She has been able to eat a couple meals without feeling ill after several bites since Thursday but the nausea is still dominating her life. Just wondering if anyone else had dealt with this problem. On the plus side, her inflammation has deminished by over 50% since she was diagnosed about 6 months ago and she has never had any joint damage. Thanks, Vicki --------------------------------- Looking for last minute shopping deals? Find them fast with Search. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 23, 2008 Report Share Posted March 23, 2008 if she is taking the meth. pills that most likely it. she's a lucky lady with no joint damage. that don't happen much. she might have to take the meth. shots. willowspirit26 <willowspirit26@...> wrote: Hi All- My daughter has RA and was on Methatraxate, Plaquinil(sp), Celebrex, Folic acid supps and several pain meds and a sleeping pill, when needed. She has developed constant nausea that has lasted for the past two weeks +. Has anyone had that reaction to any of the above meds? Her rheumy took her off the Placquinil on Thursday and said taking her off the Methatraxate would be next if this didn't help in two weeks. So far it hasn't helped much at all. She has been able to eat a couple meals without feeling ill after several bites since Thursday but the nausea is still dominating her life. Just wondering if anyone else had dealt with this problem. On the plus side, her inflammation has deminished by over 50% since she was diagnosed about 6 months ago and she has never had any joint damage. Thanks, Vicki --------------------------------- Never miss a thing. Make your homepage. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 23, 2008 Report Share Posted March 23, 2008 i have had same problems with methoxerate. rita [ ] Constant Nausea Hi All- My daughter has RA and was on Methatraxate, Plaquinil(sp) , Celebrex, Folic acid supps and several pain meds and a sleeping pill, when needed. She has developed constant nausea that has lasted for the past two weeks +. Has anyone had that reaction to any of the above meds? Her rheumy took her off the Placquinil on Thursday and said taking her off the Methatraxate would be next if this didn't help in two weeks. So far it hasn't helped much at all. She has been able to eat a couple meals without feeling ill after several bites since Thursday but the nausea is still dominating her life. Just wondering if anyone else had dealt with this problem. On the plus side, her inflammation has deminished by over 50% since she was diagnosed about 6 months ago and she has never had any joint damage. Thanks, Vicki ________________________________________________________________________________\ ____ Never miss a thing. Make your home page. http://www./r/hs Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 23, 2008 Report Share Posted March 23, 2008 hi vicki,SORRY to hear your daughter is not feeling well..my name is melynda & i take the same meds as your daughter(mtx,plaquenile,folicacid,etc.)does she take the mtx at night or in the day? i do know that it needs to b taken with food & a full glass of water.i also get nauseated but im not sure what med. is causing the problem cuz ,i take TOO many of them!! MTX is BAD,it can cause your lungs to collapse,i have a HARD TIME swallowing anything i eat. i TOLD my drs.the way i feel but im still on it. i HOPE one day i can get off some of the meds i take cuz im SOOO SICK & TIRED OF ALL THE MEDS. also,maybe your daughter should try to take the mtx in the evening. i have never had a PROBLEM taking the plaquenile. good luck & i HOPE your daughter feels BETTER SOON!!! god bless,melyndagamez@...>3/23/08 11:35p.m.central time Re: [ ] Constant Nausea It's probably the methorexate I have been upped to 8 of them a week and I have had a lot of nausea but too it could be the combination of med's that she takes. In a message dated 3/23/2008 6:07:34 A.M. Mountain Daylight Time, seriouslysanibel@... writes: It is really hard to say what is causing her nausea as it could be any one or a combination of any of those medications. She is on so many pills it could be causing stomach upset or it could be the side effect of the medication themselves. Given my experience I would suspect methotrexate or the Celebrex before the plaquenil, but the doctor pulled it probably because it is usually the least effective of the three. I just started methotrexate again and it has diminished my appetite nicely throughout the week. It was better than the last time I tried and was just plain nauseated and sick for 4 - 5 days. Remember that MTX is quite the toxic drug, they use it to induce abortions and to treat a variety of cancers (in higher doses) such as lymphoma. So yes, it can cause nausea. It is nice to hear she does not have joint damage but as you said, it has only been six months. Unfortunately, she will get there at some time and at some degree. Hopefully her RA isn't extremely aggressive and she can lead a full and active life. Shandi willowspirit26 <_willowspirit26@willowspi_ (mailto:willowspirit26@...) > wrote: Hi All- My daughter has RA and was on Methatraxate, Plaquinil(sp)My daughter Folic acid supps and several pain meds and a sleeping pill, when needed. She has developed constant nausea that has lasted for the past two weeks +. Has anyone had that reaction to any of the above meds? Her rheumy took her off the Placquinil on Thursday and said taking her off the Methatraxate would be next if this didn't help in two weeks. So far it hasn't helped much at all. She has been able to eat a couple meals without feeling ill after several bites since Thursday but the nausea is still dominating her life. Just wondering if anyone else had dealt with this problem. On the plus side, her inflammation has deminished by over 50% since she was diagnosed about 6 months ago and she has never had any joint damage. Thanks, Vicki --------------------------------- Looking for last minute shopping deals? Find them fast with Search. [Non-text portions of this message have been removed] **************Create a Home Theater Like the Pros. Watch the video on AOL Home. (http://home.aol.com/diy/home-improvement-eric-stromer?video=15?ncid=aolhom00030\ 000000001) Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 24, 2008 Report Share Posted March 24, 2008 Hi, I get a lot of nausea too on the MTX, however, I take Compazine pills periodically for bad spells and this does help. What helps the most is drinking lots of water around the time of my MTX dose for that first 24 hours anyway and also salty things seem to help, weird but true. The MTX is helping me too so I don't want to quit it. We have to remember it was originally a chemotherapy drug and most chemotherapy drugs cause nausea. Granted we are not on those mega doses, but still, I am sure it will cause the nausea side effect in a lot of people. Try these little tricks mentioned above before quitting okay? I think it is really worth a try. i really noticeif I don't drink my water. Good luck. Tracie > > i have had same problems with methoxerate. rita > > > > [ ] Constant Nausea > > Hi All- > > My daughter has RA and was on Methatraxate, Plaquinil(sp) , Celebrex, > Folic acid supps and several pain meds and a sleeping pill, when > needed. She has developed constant nausea that has lasted for the > past two weeks +. Has anyone had that reaction to any of the above > meds? Her rheumy took her off the Placquinil on Thursday and said > taking her off the Methatraxate would be next if this didn't help in > two weeks. So far it hasn't helped much at all. She has been able to > eat a couple meals without feeling ill after several bites since > Thursday but the nausea is still dominating her life. Just wondering > if anyone else had dealt with this problem. On the plus side, her > inflammation has deminished by over 50% since she was diagnosed about > 6 months ago and she has never had any joint damage. > > Thanks, > > Vicki > > > > > > _____________________________________________________________________ _______________ > Never miss a thing. Make your home page. > http://www./r/hs > > Quote Link to comment Share on other sites More sharing options...
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