Methotrexate and hypertension question

[Guest guest]

I am 39 years old and until a few months ago my blood pressure normally ran

about 100/60. For the past two weeks I have been having a severe 24 hour a day,

7 days a week headache and my blood pressure is running about 130-150 over

90-100. My blood pressure was also elevated about a month and a half ago, but

not to this degree.

The only thing that has changed from six months ago is that I am on 20mg

methotrexate. Has anyone had increased blood pressure as a side effect of

methotrexate?

I have a host of other issues that could cause hypertension such as

hypothyroidism, family history, depo medrol injections, etc. so it may not be

the methotrexate. I did skip my dose this past week due to a skin infection and

the pressure is down somewhat (probably due to the fact that I have been running

to the bathroom to urinate every hour for the past 24 hours). I was just

wondering if this could be a coincidence or not. Googling the issue didn't

really provide much in the way of answers- most of the hypertension reported

with methotrexate was in patients being treated for cancer at much higher doses.

~Marie