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Re: Neurontin & Lyrica

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This is a little old news on Lyrica but clarified my understanding (I

think).

Lyrica Now Available to Patients

By Kerrie | September 21, 2005

Pfizer announced today that Lyrica (pregabalin) is now available for

doctors to prescribe to patients. The drug is indicated for use for

neuropathic pain and seizures, but has also shown to improve patients'

sleep patterns. A successor to Neurontin (gabapentin), the two drugs

act similarly in the body. Of course the chemical structure is

slightly different (and beyond my understanding), but one obvious

difference is that Lyrica is more potent, which makes it effective at

lower doses. This in turn decreases the likelihood of side effects.

The FDA won't let Pfizer mention this, but Lyrica, like Neurontin, is

likely to be prescribed to headache patients off-label. And, based on

a conversation with my headache specialist, it's a potentially

exciting new option for prevention.

Even with his endorsement, I'm a little skeptical. You see, the FDA

has approved the manufacturing of gabapentin as a generic. Once the

generic is available, sales of Neurontin, also a Pfizer drug, will

drop. Lyrica could become to Neurontin like Clariniex is to Claritin.

It's too soon to tell if Lyrica will be a significant new drug for

headache patients or if it will another name-brand moneymaker. For all

our sakes, I've got my fingers crossed for the first option.

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Thank you all so much for the input. I started taking the Neurontin on Sunday.

It does dope me up quite a bit but my sister in law told me to keep taking it

and it will get better. But thank you again and I wish you all a pain free day

!!

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  • 3 months later...
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Hi Joyce,

I have had nerve pain in my hands, and back for at least the past

two years. When it first started up, I tried Neurontin. It made me

so groggy and it was very hard for me to get up in the morning for

work. My family doctor switched me to Lyrica which has helped the

pain in my hands much better. I was on it probably one year while I

was still working at a clerical job. About one year ago, I left my

clerical job and went on short-term disability due to the pain in my

hands and my need for spinal fusion surgery. They fused T10 to L5

due to a 50+ degree scoliosis last September. I have continued to

use the Lyrica because even though I have not gone back to work, I

continue to have sharp shooting pains in my hands with overuse.

Beverly from Aurora, OH

>

> From: Marietta <Mlette_97@...>

> Subject: More pain

> Scoliosis Treatment

> Date: Friday, July 25, 2008, 3:46 PM

>

> Hi,

> I'm still new to the group and am not the best in

> keeping up...

>

> I had aqua therapy Tuesday night for the first time.

> I was hurting a bit while doing this and asked the

> therapist about this. The next morning I woke up and

> felt wonderful! No pain! Pain didn't start until

> after I did a couple of errands around town and was

> headed in to work. But even then it wasn't bad. That

> was Wednesday morning. Thursday morning and this

> morning I've woken up basically screaming and crying

> with pain from head to foot. I feel like it is hard

> to move and every muscle hurts. An hour after I take

> my morning meds I'm usually okay but still feeling

> achy and like I really can't do anything any more. Is

> this from the aqua therapy I had 3 days ago? Is it

> from my meds I'm taking for pain? Right now I'm up to

> 1200 mg neurontin, 4 percocets and 200 mg provigil (I

> know this doesn't have anything to do with pain but it

> seems to help the pain settle down). In addition, I

> know I am depressed and I take 60 mg of cymbalta for

> that. Is this just a reaction that I'm having because

> both DH and DS are not home? I'm used to DH not being

> home but this is the first time DS (16 yo) been away

> when he's not with his relatives. I'm confused. I

> don't know what to do. I feel like I have to back out

> of all my commitments and I just can't do anything any

> more. Suggestions? I'm desparate.

>

> Thanks,

> Marietta

>

>

>

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Hi Joyce,

I don't think I ever got over the morning drag and I did not get

enough pain relief from neurontin.

Bev

> >

> > From: Marietta <Mlette_97@>

> > Subject: More pain

> > Scoliosis Treatment

> > Date: Friday, July 25, 2008, 3:46 PM

> >

> > Hi,

> > I'm still new to the group and am not the best in

> > keeping up...

> >

> > I had aqua therapy Tuesday night for the first time.

> > I was hurting a bit while doing this and asked the

> > therapist about this. The next morning I woke up and

> > felt wonderful! No pain! Pain didn't start until

> > after I did a couple of errands around town and was

> > headed in to work. But even then it wasn't bad. That

> > was Wednesday morning. Thursday morning and this

> > morning I've woken up basically screaming and crying

> > with pain from head to foot. I feel like it is hard

> > to move and every muscle hurts. An hour after I take

> > my morning meds I'm usually okay but still feeling

> > achy and like I really can't do anything any more. Is

> > this from the aqua therapy I had 3 days ago? Is it

> > from my meds I'm taking for pain? Right now I'm up to

> > 1200 mg neurontin, 4 percocets and 200 mg provigil (I

> > know this doesn't have anything to do with pain but it

> > seems to help the pain settle down). In addition, I

> > know I am depressed and I take 60 mg of cymbalta for

> > that. Is this just a reaction that I'm having because

> > both DH and DS are not home? I'm used to DH not being

> > home but this is the first time DS (16 yo) been away

> > when he's not with his relatives. I'm confused. I

> > don't know what to do. I feel like I have to back out

> > of all my commitments and I just can't do anything any

> > more. Suggestions? I'm desparate.

> >

> > Thanks,

> > Marietta

> >

> >

> >

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Hi everyone

I'm new to this group. I've been on both Neurontin and Lyrica for Fibromyalgia

and really bad pain in my back (I had Harrington rods put in 27 years ago and

now my body has done it's own compensating.) I got up to 1800mg of Neurontin a

day with a WHOLE lot of pain relief but I just kept getting dumber and dumber.

It finally got to the point where I got lost four city blocks from my house. And

it made me mean. I mean, normally I am a very peaceful, quiet person but I was

actually yelling at my roommate shortly before I quit taking it. Not me at all.

My doctor started me on Lyrica and gradually increased the dose to 300 mg a day

but it started making me stupid just like the Neurontin. I decreased to 150mg a

day and don't have a problem with it. Some pain relief with it. No other side

effects from either medication.

I just went through a six week stint at a pain control center (P.T., O.T., and

psychologist) going three times a week. Did quite a bit of good but I'm still

relying on the good 'ole trusted Hydrocodone.

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